Study of bonding methods for flip chip and beam leaded devices

The results are presented of a comprehensive study and evaluation for the bonding of flip chip and beam leaded devices onto hybrid microcircuit substrates used in high reliability space applications. The program included the evaluation of aluminum flip chips, solder (silver/tin) bump chips, gold beam leaded devices, and aluminum beam leaded devices

NASA micromin computer Monthly progress letter, Jan. 1967

Microminiature circuit development for flight control computer

Nucleation and Growth of GaN/AlN Quantum Dots

We study the nucleation of GaN islands grown by plasma-assisted molecular-beam epitaxy on AlN(0001) in a Stranski-Krastanov mode. In particular, we assess the variation of their height and density as a function of GaN coverage. We show that the GaN growth passes four stages: initially, the growth is layer-by-layer; subsequently, two-dimensional precursor islands form, which transform into genuine three-dimensional islands. During the latter stage, island height and density increase with GaN coverage until the density saturates. During further GaN growth, the density remains constant and a bimodal height distribution appears. The variation of island height and density as a function of substrate temperature is discussed in the framework of an equilibrium model for Stranski-Krastanov growth.Comment: Submitted to PRB, 10 pages, 15 figure

Comparison of quantum mechanical and classical trajectory calculations of cross sections for ion-atom impact ionization of negative - and positive -ions for heavy ion fusion applications

Stripping cross sections in nitrogen have been calculated using the classical trajectory approximation and the Born approximation of quantum mechanics for the outer shell electrons of 3.2GeV I$^{-}$ and Cs$^{+}$ ions. A large difference in cross section, up to a factor of six, calculated in quantum mechanics and classical mechanics, has been obtained. Because at such high velocities the Born approximation is well validated, the classical trajectory approach fails to correctly predict the stripping cross sections at high energies for electron orbitals with low ionization potential.Comment: submitted to Phys. Rev.

Self Calibration of Tomographic Weak Lensing for the Physics of Baryons to Constrain Dark Energy

Numerical studies indicate that uncertainties in the treatment of baryonic physics can affect predictions for shear power spectra at a level that is significant for forthcoming surveys such as DES, SNAP, and LSST. Correspondingly, we show that baryonic effects can significantly bias dark energy parameter measurements. Eliminating such biases by neglecting information in multipoles beyond several hundred leads to weaker parameter constraints by a factor of approximately 2 to 3 compared with using information out to multipoles of several thousand. Fortunately, the same numerical studies that explore the influence of baryons indicate that they primarily affect power spectra by altering halo structure through the relation between halo mass and mean effective halo concentration. We explore the ability of future weak lensing surveys to constrain both the internal structures of halos and the properties of the dark energy simultaneously as a first step toward self calibrating for the physics of baryons. This greatly reduces parameter biases and no parameter constraint is degraded by more than 40% in the case of LSST or 30% in the cases of SNAP or DES. Modest prior knowledge of the halo concentration relation greatly improves even these forecasts. Additionally, we find that these surveys can constrain effective halo concentrations near m~10^14 Msun/h and z~0.2 to better than 10% with shear power spectra alone. These results suggest that inferring dark energy parameters with measurements of shear power spectra can be made robust to baryonic effects and may simultaneously be competitive with other methods to inform models of galaxy formation. (Abridged)Comment: 18 pages, 11 figures. Minor changes reflecting referee's comments. Results and conclusions unchanged. Accepted for publication in Physical Review

Void Growth in BCC Metals Simulated with Molecular Dynamics using the Finnis-Sinclair Potential

The process of fracture in ductile metals involves the nucleation, growth, and linking of voids. This process takes place both at the low rates involved in typical engineering applications and at the high rates associated with dynamic fracture processes such as spallation. Here we study the growth of a void in a single crystal at high rates using molecular dynamics (MD) based on Finnis-Sinclair interatomic potentials for the body-centred cubic (bcc) metals V, Nb, Mo, Ta, and W. The use of the Finnis-Sinclair potential enables the study of plasticity associated with void growth at the atomic level at room temperature and strain rates from 10^9/s down to 10^6/s and systems as large as 128 million atoms. The atomistic systems are observed to undergo a transition from twinning at the higher end of this range to dislocation flow at the lower end. We analyze the simulations for the specific mechanisms of plasticity associated with void growth as dislocation loops are punched out to accommodate the growing void. We also analyse the process of nucleation and growth of voids in simulations of nanocrystalline Ta expanding at different strain rates. We comment on differences in the plasticity associated with void growth in the bcc metals compared to earlier studies in face-centred cubic (fcc) metals.Comment: 24 pages, 12 figure

Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists

PURPOSE: The ferret cisplatin emesis model has been used for ~30 years and enabled identification of clinically used anti-emetics. We provide an objective assessment of this model including efficacy of 5-HT(3) receptor antagonists to assess its translational validity. METHODS: A systematic review identified available evidence and was used to perform meta-analyses. RESULTS: Of 182 potentially relevant publications, 115 reported cisplatin-induced emesis in ferrets and 68 were included in the analysis. The majority (n = 53) used a 10 mg kg(−1) dose to induce acute emesis, which peaked after 2 h. More recent studies (n = 11) also used 5 mg kg(−1), which induced a biphasic response peaking at 12 h and 48 h. Overall, 5-HT(3) receptor antagonists reduced cisplatin (5 mg kg(−1)) emesis by 68% (45–91%) during the acute phase (day 1) and by 67% (48–86%) and 53% (38–68%, all P < 0.001), during the delayed phase (days 2, 3). In an analysis focused on the acute phase, the efficacy of ondansetron was dependent on the dosage and observation period but not on the dose of cisplatin. CONCLUSION: Our analysis enabled novel findings to be extracted from the literature including factors which may impact on the applicability of preclinical results to humans. It reveals that the efficacy of ondansetron is similar against low and high doses of cisplatin. Additionally, we showed that 5-HT(3) receptor antagonists have a similar efficacy during acute and delayed emesis, which provides a novel insight into the pharmacology of delayed emesis in the ferret

Viking navigation

A comprehensive description of the navigation of the Viking spacecraft throughout their flight from Earth launch to Mars landing is given. The flight path design, actual inflight control, and postflight reconstruction are discussed in detail. The preflight analyses upon which the operational strategies and performance predictions were based are discussed. The inflight results are then discussed and compared with the preflight predictions and, finally, the results of any postflight analyses are presented

Supersymmetric String Waves

We present plane-wave-type solutions of the lowest order superstring effective action which have unbroken space-time supersymmetries. They describe dilaton, axion and gauge fields in a stringy generalization of the Brinkmann metric. Some conspiracy between the metric and the axion field is required. We show that there exists a special class of these solutions, for which $\alpha^\prime$ stringy corrections to the effective on-shell action, to the equations of motion (and therefore to the solutions themselves), and to the supersymmetry transformations vanish. We call these solutions supersymmetric string waves (SSW).Comment: 19 pages, LaTeX, SU-ITP-92-30 and UG-10/9