A model for the anisotropic response of fibrous soft tissues using six discrete fibre bundles

The development of accurate constitutive models of fibrous soft-tissues is a challenging problem. Many consider the tissue to be a collection of fibres with a continuous distribution function representing their orientations. A novel discrete fibre model is presented consisting of six weighted fibre bundles. Each bundle is oriented such that they pass through opposing vertices of a regular icosahedron. A novel aspect of the model is the use of simple analytical distribution functions to simulate the undulated collagen fibres. This approach yields a closed form analytical expression for the strain energy function for the collagen fibre bundle that avoids the sometimes costly numerical integration of some statistical distribution functions. The elastin fibres are characterized by a neo-Hookean strain energy function. The model accurately simulates the biaxial stretching of rabbit-skin (error-of-fit 8.7%), the uniaxial stretching of pig-skin (error-of-fit 7.6%), equibiaxial loading of aortic valve cusp (error-of-fit 0.8%), and the simple shear of rat septal myocardium (error-of-fit 9.1%). The proposed model compares favourably with previously published soft-tissue models and alternative methods of representing undulated collagen fibres. The stiffness of collagen fibres predicted by the model ranges from 8.0 MPa to 0.93 GPa. The stiffness of elastin fibres ranges from 2.5 kPa to 154.4 kPa. The anisotropy of model resulting from the representation of the fibre field with a discrete number of fibres is also explored

Identifying the Burdens and Opportunities for Tribes and Communities in Federal Facility Cleanup Activities: Environmental Remediation Technology Assessment Matrix For Tribal and Community Decision-Makers

The cleanup of this country's federal facilities can affect a wide range of tribal and community interests and concerns. The technologies now in use, or being proposed by the Department of Energy, Department of Defense and other federal agencies can affect tribal treaty protected fishing, hunting and other rights, affect air and water quality thereby requiring the tribe to bear the burden of increased environmental regulation. The International Institute for Indigenous Resource Management developed a tribal and community decision-maker's Environmental Remediation Technology Assessment Matrix that will permit tribes and communities to array technical information about environmental remediation technologies against a backdrop of tribal and community environmental, health and safety, cultural, religious, treaty and other concerns and interests. Ultimately, the matrix will allow tribes and communities to assess the impact of proposed technologies on the wide range of tribal and community interests and will promote more informed participation in federal facility cleanup activities

Acute pulmonary pathology and sudden death in rats following the intravenous administration of the plasticizer, DI (2-ethylhexyl) phthalate, solubilized with Tween surfactants

Intravenous administration of 200-300 mg/kg of di(2-ethylhexyl)phthalate (DEHP) solubilized in aqueous solutions of several Tween surfactants caused respiratory distress in rats. There was a dose-dependent lethality with death generally occurring within 90 minutes after injection. The lungs from DEHP:Tween treated animals were enlarged, generally darkened, and in some cases showed hemorrhagic congestion. Neither the overt symptoms nor the morphologic alterations resulting from DEHP:Tween administration could be reproduced by intravenous administration of aqueous Tween solutions alone. The absence of pulmonary abnormalities following the intravenous administration of DEHP as an aqueous emulsion given either alone or even as soon as 2 minutes after pretreatment with Tween 80, suggests that the specific in vivo interaction between DEHP and Tween surfactants depends on the prior formation of water-soluble micelles of DEHP

Gravitational Wave Bursts from Collisions of Primordial Black Holes in Clusters

The rate of gravitational wave bursts from the mergers of massive primordial black holes in clusters is calculated. Such clusters of black holes can be formed through phase transitions in the early Universe. The central black holes in clusters can serve as the seeds of supermassive black holes in galactic nuclei. The expected burst detection rate by the LISA gravitational wave detector is estimated.Comment: 10 pages, 2 figure

Quantum Nonlocality: Not Eliminated by the Heisenberg Picture

It is argued that the Heisenberg picture of standard quantum mechanics does not save Einstein locality as claimed in Deutsch and Hayden (2000). In particular, the EPR-type correlations that DH obtain by comparing two qubits in a local manner are shown to exist before that comparison. In view of this result, the local comparison argument would appear to ineffective in supporting their locality claim.Comment: Final version; to appear in Foundations of Physic

Emerging areas of research reported during the CDC National Conference on Pfiesteria: From biology to public health

Since its identification in 1996, the marine dinoflagellate Pfiesteria piscicida Steidinger & Burkholder has been the focus of intense scientific inquiry in disciplines ranging from estuarine ecology to epidemiology and from molecular biology to public health. Despite these research efforts, the extent of human exposure and the degree of human illness directly associated with Pfiesteria is still in the process of being defined. Unfortunately, during this same time Pfiesteria has also stimulated media coverage that in some instances jumped ahead of the science to conclude that Pfiesteria presents a widespread threat to human health. Political and economic forces also came into play when the tourism and seafood industries were adversely impacted by rumors of toxin-laden water in estuaries along the east coast of the United States. Amid this climate of evolving science and public concern, Pfiesteria has emerged as a highly controversial public health issue. In October 2000 Centers for Disease Control and Prevention sponsored the National Conference on Pfiesteria: From Biology to Public Health to bring together Pfiesteria researchers from many disparate disciplines. The goal of this meeting was to describe the state of the science and identify directions for future research. In preparation for the conference an expert peer-review panel was commissioned to review the existing literature and identify research gaps; the summary of their review is published in this monograph. During the meeting primary Pfiesteria researchers presented previously unpublished results. The majority of those presentations are included as peer-reviewed articles in this monograph. The discussion portion of the conference focused upon researcher-identified research gaps. This article details the discussion segments of the conference and makes reference to the presentations as it describes emerging areas of Pfiesteria research

Scout motor performance analysis and prediction study /PAPS/

Scout motor performance analysis and predictio

Visualization of hydrogen injection in a scramjet engine by simultaneous PLIF imaging and laser holographic imaging

Flowfield characterization has been accomplished for several fuel injector configurations using simultaneous planar laser induced fluorescence (PLIF) and laser holographic imaging (LHI). The experiments were carried out in the GASL-NASA HYPULSE real gas expansion tube facility, a pulsed facility with steady test times of about 350 microsec. The tests were done at simulated Mach numbers 13.5 and 17. The focus of this paper is on the measurement technologies used and their application in a research facility. The HYPULSE facility, the models used for the experiments, and the setup for the LHI and PLIF measurements are described. Measurement challenges and solutions are discussed. Results are presented for experiments with several fuel injector configurations and several equivalence ratios

Mechanisms of rolling contact spalling

The results of a study aimed at analyzing the mechanical material interactions responsible for rolling contact spalling of the 440 C steel, high pressure oxygen turbopump bearings are presented. A coupled temperature displacement finite element analysis of the effects of friction heating under the contact is presented. The contact is modelled as a stationary, heat generating, 2 dimensional indent in an elastic perfectly plastic half-space with heat fluxes up to 8.6 x 10000 KW/m sq comparable to those generated in the bearing. Local temperatures in excess of 1000 C are treated. The calculations reveal high levels of residual tension after the contact is unloaded and cools. Efforts to promote Mode 2/Mode 3 fatigue crack growth under cyclic torsion in hardened 440 C steel are described. Spalls produced on 440 C steel by a 3 ball/rod rolling contact testing machine were studied with scanning microscopy. The shapes of the cyclic, stress strain hysteresis loops displayed by hardened 440 C steel in cyclic torsion at room temperature are defined for the plastic strain amplitudes encountered in rolling/sliding contact. Results of these analyses are discussed in detail

Open Questions in Classical Gravity

We discuss some outstanding open questions regarding the validity and uniqueness of the standard second order Newton-Einstein classical gravitational theory. On the observational side we discuss the degree to which the realm of validity of Newton's Law of Gravity can actually be extended to distances much larger than the solar system distance scales on which the law was originally established. On the theoretical side we identify some commonly accepted but actually still open to question assumptions which go into the formulating of the standard second order Einstein theory in the first place. In particular, we show that while the familiar second order Poisson gravitational equation (and accordingly its second order covariant Einstein generalization) may be sufficient to yield Newton's Law of Gravity they are not in fact necessary. The standard theory thus still awaits the identification of some principle which would then make it necessary too. We show that current observational information does not exclusively mandate the standard theory, and that the conformal invariant fourth order theory of gravity considered recently by Mannheim and Kazanas is also able to meet the constraints of data, and in fact to do so without the need for any so far unobserved non-luminous or dark matter.Comment: UCONN-93-1, plain TeX format, 22 pages (plus 7 figures - send requests to [email protected]). To appear in a special issue of Foundations of Physics honoring Professor Fritz Rohrlich on the occasion of his retirement, L. P. Horwitz and A. van der Merwe Editors, Plenum Publishing Company, N.Y., Fall 199