PLOS ONE / Clinical presentation and management of stable coronary artery disease in Austria

Background Cardiovascular disease is the main cause of death in Austria. However, no systematic information exists regarding characteristics and treatments of contemporary patients with stable coronary artery disease (CAD) in Austria. We assembled two retrospective physicians databases to describe demographics, clinical profiles, and therapeutic strategies in patients with stable CAD. In addition, we compared patient profiles of secondary care internists and hospital-based cardiologists with those of general practitioners in a primary care setting outside of hospital. Methods The study population was identified from retrospective chart review of 1020 patients from 106 primary care physicians in Austria (ProCor II registry), and was merged with a previous similar database of 1280 patients under secondary care (ProCor I registry) to yield a total patient number of 2300. Results Female patients with stable CAD were older, had more angina and/or heart failure symptoms, and more depression than males. Female gender, type 2 diabetes mellitus, higher CCS class and asthma/COPD were predictors of elevated heart rate, while previous coronary events/revascularization predicted a lower heart rate in multivariate analysis. There were no significant differences with regard to characteristics and management of patients of general practitioners in the primary care setting versus internists in secondary care. Conclusions Characteristics and treatments of unselected patients with stable ischemic heart disease in Austria resemble the pattern of large international registries of stable ischemic heart disease, with the exception that diabetes and systemic hypertension were more prevalent.(VLID)486957

Characteristics of the ProCor II study population by gender.

<p>Characteristics of the ProCor II study population by gender.</p

Cardiovascular disease characteristics.

<p>Cardiovascular disease characteristics.</p

Regression estimates and confidence intervals of simple models analyzing predictors of heart rate in ProCor I (blue) and ProCor II (red).

<p>The effect of age is shown in HR change per 10 years. Female denotes female gender.</p

Ischemic heart disease medications.

<p>Ischemic heart disease medications.</p

Regression estimates and confidence intervals resulting from multiple imputations and variable selections applied to the pooled data from ProCor I and ProCor II.

<p>Female denotes female gender.</p

Regression estimates and confidence intervals of simple models analyzing predictors of heart rate using variables that were unique to the ProCor II dataset.

<p>Regression estimates and confidence intervals of simple models analyzing predictors of heart rate using variables that were unique to the ProCor II dataset.</p

SUPRA - Enhanced Upset Recovery Simulation

The SUPRA research project – Simulation of Upset Recovery in Aviation – has been funded by the European Union the Framework Program to enhance the flight simulation envelope for upset recovery simulation. Within the project an extended aerodynamic model, capturing the key aerodynamics during and beyond stall for a large category transport aircraft and new motion cueing solutions for both hexapod and centrifuge-based platforms were developed. This paper describes the recent piloted evaluation experiments. In the first experiment a group of ten experimental test pilots, with actual experience in stall conditions, subjectively judged the validity of the aerodynamic model and the motion cueing solutions in the simulators in different upset conditions. Pilots rated the stall behaviour of the SUPRA