Assessment of Spatio-Temporal Variations in PM\u3csub\u3e2.5\u3c/sub\u3e and Associated Long-Range Air Mass Transport and Mortality in South Asia

Fine particulate matter (PM2.5) is associated with adverse impacts on ambient air quality and human mortality; the situation is especially dire in developing countries experiencing rapid industrialization and urban development. This study assessed the spatio-temporal variations of PM2.5 and its health impacts in the South Asian region. Both satellite and station-based data were used to monitor the variations in PM2.5 over time. Additionally, mortality data associated with ambient particulate matter were used to depict the overall impacts of air pollution in this region. We applied the Mann–Kendall and Sen’s slope trend analysis tool to investigate the trend of PM2.5. At the same time, clustering of backward trajectories was used for identifying the long-range air mass transport. The results revealed that the mean annual PM2.5 mass concentration was the highest (46.72 µg/m3) in Bangladesh among the South Asian countries during 1998–2019, exceeding the national ambient air quality standards of Bangladesh (i.e., 15 µg/m3) and WHO (10 µg/m3), while lower PM2.5 was observed in the Maldives and Sri Lanka (5.35 µg/m3 and 8.69 µg/m3, respectively) compared with the WHO standard. The trend analysis during 1998–2019 suggested that all South Asian countries except the Maldives experienced an increasing trend (p \u3c 0.05) of PM2.5. The study showed that among the major cities, the mean annual PM2.5 value was the highest in New Delhi (110 µg/m3), followed by Dhaka (85 µg/m3). Regarding seasonal variation, the highest PM2.5 was found during the pre-monsoon season in all cities. The findings of this research would help the concerned governments of South Asian countries to take steps toward improving air quality through policy interventions or reforms. Moreover, the results would provide future research directions for studying the trend and transport of atmospheric PM2.5 in other regions

The Impact of Brick Kiln Operation to the Degradation of Topsoil Quality of Agricultural Land

Brick kiln is a big environmental issue for the agriculture of Bangladesh as it was observed that the agricultural production in the soil close to the brick kiln was lesser than the same soil far from brick kiln. The study was conducted to assess the impact of brick kiln operation to the degradation of topsoil quality at Singair of Kalihati upazila in Tangail, Bangladesh, during the period of July to December 2013. The Soil was collected from areas close to the brick fields and far from the brick fields at a depth of 0-15 cm. The Electrical Conductance (EC) was found almost double in the soil samples close to the brick field than the soil samples far from brick field. The organic mattter content in the soil sample close to the brickfield was significantly lower than that of the far soil sample. The mean values of total N, available P and S were also significantly lower in the soil samples close to the brick kiln, 0.05%, 12.4, and 8.36 ppm respectively in the close soils, while 0.06%, 24.6, and 11.7 ppm respectively in the far soil. There were no significant changes observed in the other elements

Maternal Genome-Wide DNA Methylation Patterns and Congenital Heart Defects

The majority of congenital heart defects (CHDs) are thought to result from the interaction between multiple genetic, epigenetic, environmental, and lifestyle factors. Epigenetic mechanisms are attractive targets in the study of complex diseases because they may be altered by environmental factors and dietary interventions. We conducted a population based, case-control study of genome-wide maternal DNA methylation to determine if alterations in gene-specific methylation were associated with CHDs. Using the Illumina Infinium Human Methylation27 BeadChip, we assessed maternal gene-specific methylation in over 27,000 CpG sites from DNA isolated from peripheral blood lymphocytes. Our study sample included 180 mothers with non-syndromic CHD-affected pregnancies (cases) and 187 mothers with unaffected pregnancies (controls). Using a multi-factorial statistical model, we observed differential methylation between cases and controls at multiple CpG sites, although no CpG site reached the most stringent level of genome-wide statistical significance. The majority of differentially methylated CpG sites were hypermethylated in cases and located within CpG islands. Gene Set Enrichment Analysis (GSEA) revealed that the genes of interest were enriched in multiple biological processes involved in fetal development. Associations with canonical pathways previously shown to be involved in fetal organogenesis were also observed. We present preliminary evidence that alterations in maternal DNA methylation may be associated with CHDs. Our results suggest that further studies involving maternal epigenetic patterns and CHDs are warranted. Multiple candidate processes and pathways for future study have been identified

Women’s involvement in Organic (Vegetables) Farming System Activities (OFSA) in Samsung district of North-East Thailand

This study was designed to determine the extent of involvement that women have in regards to OFSA, as well as explore the relationships between women involved with OFSA and the characteristics they possess. The study was conducted in two villages, Ban Samoang and Ban Sawang in the Samsung District of Northeast of Thailand. One hundred women were randomly selected as a sample from a population of 300. The findings reveal that about three-quarters (70%) of the women have medium to high level of involvement in OFSA, while 30% have low level involvement. The co-relation indicates that age, annual family income, family size, education, training exposure, farming experience and knowledge of farming system of the respondents are positively co-related with their involvement of OFSA. The co-relation also indicates that farm size is negatively co-related with their involvement. The study suggests that problems of women’s involvement in organic vegetables cultivation include lack of knowledge on organic farming system, scarcity of money, limited cooperation, shortage of skilled labor, price of organic vegetables, lack of suitable agricultural machinery for women, and insufficient training. This study recommends women involved in cultivation also face barriers including-sufficient training on production systems, available financial support to the farmers, suitable agricultural instruments and ensuring satisfactory price of organic vegetables will be helpful for organic vegetables cultivation

THE IMPACT OF BRICK KILN OPERATION TO THE DEGRADATION OF TOPSOIL QUALITY OF AGRICULTURAL LAND

Brick kiln is a big environmental issue for the agriculture of Bangladesh as it was observed that the agricultural production in the soil close to the brick kiln was lesser than the same soil far from brick kiln. The study was conducted to assess the impact of brick kiln operation to the degradation of topsoil quality at Singair of Kalihati upazila in Tangail, Bangladesh, during the period of July to December 2013. The Soil was collected from areas close to the brick fields and far from the brick fields at a depth of 0-15 cm. The Electrical Conductance (EC) was found almost double in the soil samples close to the brick field than the soil samples far from brick field. The organic mattter content in the soil sample close to the brickfield was significantly lower than that of the far soil sample. The mean values of total N, available P and S were also significantly lower in the soil samples close to the brick kiln, 0.05%, 12.4, and 8.36 ppm respectively in the close soils, while 0.06%, 24.6, and 11.7 ppm respectively in the far soil. There were no significant changes observed in the other elements