1,361 research outputs found

    Gluon Fragmentation to Gluonium

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    The fragmentation of gluons to gluonium states is analyzed qualitatively in the non-perturbative region. The convolution of this mechanism with perturbative gluon radiation leaves us with a hard component in the fragmentation of gluon to gluonium.Comment: 6 pages with 2 figures, LaTe

    Isolation of anaerobic, extremely thermophilic, sulphur metabolising archaebacteria from New Zealand hot springs

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    Enrichments of New Zealand geo-thermal samples, initiated in anaerobic sulphur-containing media and incubated at temperatures above 85°C, yielded rod and coccal shaped organisms which possessed archaebacterial characteristics. Pure cultures were isolated and characterised. Five of the seven isolates, which were rod-shaped organisms and did not have an obligate requirement for sulphur respiration, were similar to Ther-moproteus sp. but had more neutral pH optima for growth. Three of these five Thermoproteus sp. were obligate heterotrophs, which has not previously been reported. The two coccal isolates had an obligate requirement for sulphur as an electron acceptor and were similar to Desulfurococcus sp. but again with more neutral pH optima for growth

    Diagnosis of venous thromboembolism

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    International audienc

    AN ANALYTICAL FRAMEWORK FOR DISCUSSING FARM BUSINESS INTERRUPTION INSURANCE FOR CLASSICAL SWINE FEVER

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    This paper studies farm business interruption insurance for Classical Swine Fever epidemics. Insight into the size of risk is obtained by a very detailed Monte-Carlo simulation model that includes both epidemiological and economic factors. The paper also considers issues such as farmers' and governments' influence on the size of risk.Livestock Production/Industries, Risk and Uncertainty,

    Mineralogical Alterations During Laboratory-scale Carbon Sequestration Experiments for the Illinois Basin

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    AbstractDuring geological sequestration of carbon dioxide, the injected CO2 will react with formation fluids and rocks in the injection zone and overlying cap rocks. The resulting acidification of the fluids may result in the dissolution of solid phases and the formation of new solid phases which can cause changes in rock composition and overall fabric. We are conducting laboratory-scale geochemical and mineralogical studies on reservoir and cap rock samples in the Illinois Basin that complement the on-going Illinois Basin - Decatur Project (IBDP), a large-scale one million tonne demonstration of geologic sequestration in the Mt Simon Sandstone, Illinois USA. Mt. Simon Sandstone, Eau Clare Shale, and Knox Supergroup samples from the IBDP injection and deep monitoring wells and locations with rocks analogous to those at the IBDP site have been selected for simulated reactions using synthetic brine and CO2 in modified Parr pressure reactors at pressure and temperature conditions that correspond to ambient reservoir conditions (9.87 to 20.7MPa and 38 to 50°C) and for varying amounts of time (1 to 9 months). Using petrographic techniques and XRD analysis, samples have been analyzed before and after reactor experiments to define the mineralogical and textural baseline and report observed changes. Brine composition has also been analyzed for geochemical changes. The ReactŸ and Differential Evolution geochemical modeling programs are being used to simulate changes in mineral mass and brine chemistry. Post-reaction analyses of rock and brine samples from the Mt. Simon Sandstone show evidence of dissolution of diagenetic clays, increased porosity, and possible illitization of clay minerals. Three, six, and nine month post-reaction Eau Claire Shale rock and brine sample analyses indicate some degree of brine-rock-CO2 reaction by showing weathered illite, mixed clay, feldspar, biotite, and pyrite crystals. Post-reaction Potosi Dolomite rock and brine samples show evidence of dissolution of dolomite. Overall, petrographic and geochemical observations from these experiments suggest that the Mt. Simon Sandstone reservoir and Eau Claire cap rock system serve as good CO2 sequestration site. The competency of the Knox Supergroup as a CO2 sequestration target is still under investigation

    Management and orientation of geriatric patients admitted to emergencies for a fall: results of the French prospective OREGoN cohort study

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    Falls in older adults are a frequent reason for admission to the emergency department, associated with greater morbidity and mortality risks, and justify specialized geriatric expertise. Our objective was to determine i) the number of older fallers admitted to the emergency department for a serious fall, and ii) the proportion of those who were referred to a geriatrician in the following 12 months. METHODS: We included all patients aged 75 and over admitted to the emergency department of the University hospital of Angers, France, for a fall between 1st October and 1st November 2015. The consensual criteria proposed by the French national authority for health (2009) were used to define serious falls. RESULTS: Of the 214 older fallers admitted to the emergency department, 213 (99.5%) had at least one severity criterion for the fall. Only 40 older patients (18.7%) were referred to a geriatrician during the following 12 months. They exhibited more frequently a post-fall syndrome (p=0.007), more than 3 fall risk factors (p <0.001), and took more often an anticoagulant (p=0.032) than those who had not been referred to a geriatrician. CONCLUSIONS: Although almost all older fallers admitted to the emergency room had experienced a serious fall, only a minority of them received a geriatric assessment in the following year

    Charge manipulation and imaging of the Mn acceptor state in GaAs by Cross-sectional Scanning Tunneling Microscopy

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    An individual Mn acceptor in GaAs is mapped by Cross-sectional Scanning Tunneling Microscopy (X-STM) at room temperature and a strongly anisotropic shape of the acceptor state is observed. An acceptor state manifests itself as a cross-like feature which we attribute to a valence hole weakly bound to the Mn ion forming the (Mn2+3d5+hole^{2+}3d^5+hole) complex. We propose that the observed anisotropy of the Mn acceptor wave-function is due to the d-wave present in the acceptor ground state.Comment: Proceedings of the SIMD-4 conference. Hawaii, USA (December 1-5, 2003

    Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

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    Mycobacteria use type VII secretion (T7S) systems to secrete proteins across their highly hydrophobic diderm cell envelope. Pathogenic mycobacteria, such as Mycobacterium tuberculosis and Mycobacterium marinum, have up to five of these systems, named ESX-1 to -5. Most of these systems contain a set of five conserved membrane components, of which the four Ecc proteins form the core membrane-embedded secretion complex. The fifth conserved membrane protein, the mycosin protease (MycP), is not part of the core complex, but is essential for secretion, as it stabilizes this membrane complex. Here, we investigated which MycP domain is required for this stabilization by producing hybrid constructs between MycP1 and MycP5 in M. marinum and analyzed their effect on ESX-1 and ESX-5 secretion. We found that both the protease and transmembrane (TM) domain are required for the ESX system-specific function of mycosins. In addition, we observed that the TM domain strongly affects MycP protein levels. We also show that the extended loops 1 and 2 in the protease domain are probably primarily involved in MycP stability, whereas loop 3 and the MycP5-specific loop 5 are dispensable. The atypical propeptide, or N-terminal extension, is required only for MycP stability. Finally, we show that the protease domain of MycPP1, encoded by the esx-P1 locus on the pRAW plasmid, is functionally redundant to the protease domain of MycP5 These results provide the first insight into the regions of mycosins involved in the interaction with and the stabilization of their respective ESX complexes

    Derivation and validation of a multivariate model to predict mortality from pulmonary embolism with cancer: The POMPE-C tool

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    BackgroundClinical guidelines recommend risk stratification of patients with acute pulmonary embolism (PE). Active cancer increases risk of PE and worsens prognosis, but also causes incidental PE that may be discovered during cancer staging. No quantitative decision instrument has been derived specifically for patients with active cancer and PE. Methods Classification and regression technique was used to reduce 25 variables prospectively collected from 408 patients with AC and PE. Selected variables were transformed into a logistic regression model, termed POMPE-C, and compared with the pulmonary embolism severity index (PESI) score to predict the outcome variable of death within 30 days. Validation was performed in an independent sample of 182 patients with active cancer and PE. Results POMPE-C included eight predictors: body mass, heart rate > 100, respiratory rate, SaO2%, respiratory distress, altered mental status, do not resuscitate status, and unilateral limb swelling. In the derivation set, the area under the ROC curve for POMPE-C was 0.84 (95% CI: 0.82-0.87), significantly greater than PESI (0.68, 0.60-0.76). In the validation sample, POMPE-C had an AUC of 0.86 (0.78-0.93). No patient with POMPE-C estimate ≀ 5% died within 30 days (0/50, 0-7%), whereas 10/13 (77%, 46-95%) with POMPE-C estimate > 50% died within 30 days. Conclusion In patients with active cancer and PE, POMPE-C demonstrated good prognostic accuracy for 30 day mortality and better performance than PESI. If validated in a large sample, POMPE-C may provide a quantitative basis to decide treatment options for PE discovered during cancer staging and with advanced cancer
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