Existence chez la pomme de terre de résistance induite vis-à-vis de Globodera rostochiensis

Le mécanisme de résistance à #G. rostochiensis Ro1/4 de deux génotypes ex-#vernei de pomme de terre et leurs parents est étudié selon diverses méthodologies. Les résultats obtenus #in vitro à partir de plantes cultivées en boîte de Petri montrent que la résistance est incomplète. Par contre, la résistance mesurée à partir de tests réalisés en pots est analogue à celle induite par le gène H1. L'influence possible des exsudats radiculaires sur ces discordances est étudiée et réfutée : pour certains génotypes, l'éclosion est supérieure à celle induite par le témoin ; pour d'autres, elle est inférieure mais la différence mesurée est insuffisante pour expliquer l'ampleur des discordances observées. Les tests #in vitro montrent en fait que l'invasion progressive des juvéniles de #G. rostochiensis induit, à partir d'une certaine quantité de juvéniles, une résistance quasi totale sur toute la longueur de la racine. Cette résistance agit alors également vis-à-vis de #G. pallida. Le rôle possible des phytoalexines ou de protéines de défense, PR, est envisagé. (Résumé d'auteur

Prototype 9.7 m Schwarzschild-Couder telescope for the Cherenkov Telescope Array: status of the optical system

The Cherenkov Telescope Array (CTA) is an international project for a next-generation ground-based gamma ray observatory, aiming to improve on the sensitivity of current-generation experiments by an order of magnitude and provide energy coverage from 30 GeV to more than 300 TeV. The 9.7m Schwarzschild-Couder (SC) candidate medium-size telescope for CTA exploits a novel aplanatic two-mirror optical design that provides a large field of view of 8 degrees and substantially improves the off-axis performance giving better angular resolution across all of the field of view with respect to single-mirror telescopes. The realization of the SC optical design implies the challenging production of large aspherical mirrors accompanied by a submillimeter-precision custom alignment system. In this contribution we report on the status of the implementation of the optical system on a prototype 9.7 m SC telescope located at the Fred Lawrence Whipple Observatory in southern Arizona.Comment: Proceedings of the 35th International Cosmic Ray Conference (ICRC 2017), Busan, Korea. All CTA contributions at arXiv:1709.0348

Uncertainty in measuring laminar burning velocity from expanding methane-air flames at low pressures

International audienceThe experimental determination of laminar burning velocity remains essential to evaluate the combustion potential of any fuels but also to validate kinetic mechanisms. Recently, researchers are making great efforts to improve the accuracy of the different setups and techniques to determine this parameter. This work proposes an attempt to summarize the different factors contributing to the uncertainty of the expanding spherical flame method. In particular, the validity of two hypothesis (adiabatic flame propagation and thin flame front) is discussed in the case of stoichiometric methane-air flames in low-pressure environment (from 0.2 to 2 bar). Last, the effect of spark electrode diameters was also considered (0.2, 0.5 and 1 mm)

AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol

OBJECTIVE: Estradiol (E2) mediates numerous beneficial effects assigned to estrogens, but whereas mechanisms have been described at the endothelial level, direct effects on vascular smooth muscle cells (VSMC) are poorly documented. As evidence accumulates regarding the role of RhoA in vascular pathophysiology and the benefit of RhoA-Rho associated protein kinase (Rock) pathway inhibition, we analyzed if E2 could inhibit it in VSMC. METHODS AND RESULTS: We show that in VSMC, E2 inhibits the RhoA-Rock pathway in a time- and concentration-dependent manner. The inhibition of RhoA-Rock pathway results from E2-induced phosphorylation of the Ser188 of RhoA. Using pharmacological, transfection, and in vitro phosphorylation experiments, we demonstrate that AMP-activated protein kinase subunit alpha 1 (AMPKalpha1) is activated by estrogen receptor stimulation and catalyzes RhoA phosphorylation induced by E2. Ex vivo, ovariectomy leads to an increase in the amplitude of phenylephrine- or serotonine-induced contractions of aortic rings in wild-type mice but not in AMPKalpha1-knock-out mice or E2-supplemented animals. These functional effects were correlated with a reduced level of RhoA phosphorylation in the aorta of ovariectomized female, male, and AMPKalpha1 knock-out mice. CONCLUSION: Our work thus defines AMPKalpha1 as (1) a new kinase for RhoA and (2) a new mediator of the vasoprotective effects of estrogen

Construction of a Schwarzschild-Couder telescope as a candidate for the Cherenkov Telescope Array: status of the optical system

We present the design and the status of procurement of the optical system of the prototype Schwarzschild-Couder telescope (pSCT), for which construction is scheduled to begin in fall at the Fred Lawrence Whipple Observatory in southern Arizona, USA. The Schwarzschild-Couder telescope is a candidate for the medium-sized telescopes of the Cherenkov Telescope Array, which utilizes imaging atmospheric Cherenkov techniques to observe gamma rays in the energy range of 60Gev-60TeV. The pSCT novel aplanatic optical system is made of two segmented aspheric mirrors. The primary mirror has 48 mirror panels with an aperture of 9.6 m, while the secondary, made of 24 panels, has an diameter of 5.4 m. The resulting point spread function (PSF) is required to be better than 4 arcmin within a field of view of 6.4 degrees (80% of the field of view), which corresponds to a physical size of 6.4 mm on the focal plane. This goal represents a challenge for the inexpensive fabrication of aspheric mirror panels and for the precise alignment of the optical system as well as for the rigidity of the optical support structure. In this submission we introduce the design of the Schwarzschild-Couder optical system and describe the solutions adopted for the manufacturing of the mirror panels and their integration with the optical support structure.Comment: In Proceedings of the 34th International Cosmic Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions at arXiv:1508.0589