How to add a RADAR resource to Moodle using the PLATO plagiarism tutorial as an example.

A 2-page guide that explains how to add a link to the PLATO plagiarism tutorial in a Brookes Virtual course. This document is intended for COURSE DESIGNERS ONLY

The evolution of RADAR

PowerPoint slides from a presentation by Steve Burholt and Rowena Rouse at the Equella Customer Advisory Board in March 2013 in London. The slides show how the RADAR repository at Oxford Brookes University has evolved to include an eclectic mix of resources

An introduction to RADAR

PowerPoint slides of a presentation by Steve Burholt and Rowena Rouse on 22 January 2010, about the RADAR project. The presentation includes information about the Research archive and Teaching collection, and also covers the technical aspects of developing a "blended" repository

The Relationship Between Extraversion and Listening Comprehension Under High and Low-Salience Visual Distraction Conditions

The proposed study contributes to the pool of research examining the link between level of extraversion and sensory stimulation. Numerous studies have shown that introverts are more susceptible to forms of auditory distraction than extraverts when completing cognitive tasks requiring visual attention, but no study has examined the opposite relationship: the differing effects of visual distraction on auditory comprehension amongst introverts and extraverts. Using undergraduate college students as participants, this study tested three hypotheses: 1) there will be a negative correlation between level of extraversion and self-reported distraction while under high-salience visual distraction, 2) there will be a positive correlation between participants’ Extraversion score and performance on a listening comprehension task while under high-salience visual distraction and 3) the aforementioned correlation will be higher than the correlation between level of extraversion and performance on a listening comprehension task while under low-salience visual distraction. Though results did not lend support to the idea of these differences in sensory stimulation applying to different forms of visual distraction, we highlight the importance of these findings and provide important suggestions for future research into a critical phenomenon with implications in educational, workplace, and social settings

Factors Associated with Academic Stimulant Misuse in a College Setting

The purpose of this study was to further understand and explore the motivations behind college students’ misuse of stimulants in an academic setting, in order to develop means to combat its growing popularity. We hypothesized that students would be more likely to misuse stimulants if 1) they perceive SM to be safe, 2) they perceive SM to be ethical, 3) they are more extrinsically motivated in an academic setting, 4) they perceive their academic environments to be competitive, and 5) they perceive SM to be normative. Participants (n = 172) were undergraduate students at a small, Christian, liberal arts university in Southern California. Participants were recruited from an online research participation management system that included students enrolled in a foundational psychology course. The online survey was anonymous and took approximately 15 minutes to complete. The survey questionnaires were administered online in the following order: The Demographic Form, the Academic Motivation Scale, the Perceived Campus Competitiveness scale, the Stimulant Use Questionnaire, the Modified Perception of Prescription Misuse Among Peers scale, the Perception of Safety of Stimulants scale, the Perceptions of Adderall Ethicality scale, and the Validity Question. Descriptive statistics evaluated attitudes and perceptions of SM safety, commonality, and ethicality. Only 43.6% of participants viewed alcohol to be safer than SM. While only 10.5% of participants reported lifetime SM, 61.6% of students perceived less than half, about half, or more than half of students to misuse stimulants during finals week. Finally, only 35.4% of students actually viewed SM as academic dishonesty

Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer

Funding: Wellcome Trust Investigator Awards (098391/Z/12/Z and 217196/Z/19/Z) and Cancer Research UK Programme grant (C434/A21747) to R.T.H., Wellcome Trust Studentship (109113/Z/15/Z) to P.M., Wellcome Trust Collaborative Award (215539) and multiuser equipment grant (104833) to S.J.M. Additionally J.C.P. thanks the Scottish Universities Physics Alliance (SUPA) and the University of St. Andrews for financial support.The human genome contains an estimated 600 ubiquitin E3 ligases, many of which are single-subunit E3s (ssE3s) that can bind to both substrate and ubiquitin-loaded E2 (E2~Ub). Within ssE3s structural disorder tends to be located in substrate binding and domain linking regions. RNF4 is a ssE3 ligase with a C-terminal RING domain and disordered N-terminal region containing SUMO Interactions Motifs (SIMs) required to bind SUMO modified substrates. Here we show that, although the N-terminal region of RNF4 bears no secondary structure, it maintains a compact global architecture primed for SUMO interaction. Segregated charged regions within the RNF4 N-terminus promote compaction, juxtaposing RING domain and SIMs to facilitate substrate ubiquitination. Mutations that induce a more extended shape reduce ubiquitination activity. Our result offer insight into a key step in substrate ubiquitination by a member of the largest ubiquitin ligase subtype and reveal how a defined architecture within a disordered region contributes to E3 ligase function.Publisher PDFPeer reviewe

Evaluation of delivery options for second-stage events

Cesarean delivery in the second stage of labor is common, whereas the frequency of operative vaginal delivery has been declining. However, data comparing outcomes for attempted operative vaginal delivery in the second stage versus cesarean in the second stage are scant. Previous studies that examine operative vaginal delivery have compared it to a baseline risk of complications from a spontaneous vaginal delivery and cesarean delivery. However, when a woman has a need for intervention in the second stage, spontaneous vaginal delivery is not an option she or the provider can choose. Thus, the appropriate clinical comparison is cesarean versus operative vaginal delivery

Risk of Uterine Rupture and Placenta Accreta With Prior Uterine Surgery Outside of the Lower Segment

Objective—Women with a prior myomectomy or prior classical cesarean delivery are often delivered early by cesarean due to concern for uterine rupture. Although theoretically at increased risk for placenta accreta, this risk has not been well quantified. Our objective was to estimate and compare the risks of uterine rupture and placenta accreta in women with prior uterine surgery. Methods—Women with prior myomectomy or prior classical cesarean delivery were compared to women with a prior low transverse cesarean to estimate rates of both uterine rupture and placenta accreta. Results—One hundred seventy-six women with a prior myomectomy, 455 with a prior classical cesarean delivery, and 13,273 women with a prior low transverse cesarean were evaluated. Mean gestational age at delivery differed by group (p0.99) or in the prior classical cesarean delivery group (0.88%, p=0.13). Placenta accreta occurred in 0% (95% CI 0-1.98%) of prior myomectomy compared with 0.19% in the low transverse cesarean group (p>0.99) and 0.88% in the prior classical cesarean delivery group (p=0.01 relative to low transverse cesarean). The adjusted OR for the prior classical cesarean delivery group (relative to low transverse cesarean) was 3.23 (1.11-9.39) for uterine rupture and 2.09 (0.69-6.33) for accreta. The frequency of accreta for those with previa was 11.1% for the prior classical cesarean delivery and 13.6% for low transverse cesarean groups (p>0.99=1.0). Conclusion—A prior myomectomy is not associated with higher risks of either uterine rupture or placenta accreta. The absolute risks of uterine rupture and accreta after prior myomectomy are low

Relationship Between Excessive Gestational Weight Gain and Neonatal Adiposity in Women With Mild Gestational Diabetes Mellitus:

To evaluate the relationships between excessive gestational weight gain, neonatal adiposity, and adverse obstetric outcomes in women with mild gestational diabetes mellitus (GDM)

Prediction of Spontaneous Preterm Birth Among Nulliparous Women With a Short Cervix

To evaluate whether demographic and sonographic factors associated with spontaneous preterm birth (sPTB) among nulliparous women with a cervical length (CL) < 30 mm could be combined into an accurate prediction model for sPTB