The Business Environment of 1995 as Seen by Wisconsin Business Executives

Like many states, particularly those in the so-called rust bucket of the industrial north, Wisconsin is concerned about its business climate. A number of different steps with the potential to make Wisconsin\u27s business environment more hospitable have been taken. For example, the state income tax has been reduced; the state has partially funded a business development organization, Forward Wisconsin, to attract new companies to the area; and a state-appointed panel, the Wisconsin Strategic Development Commission, has filed its recommendations concerning the actions that should be considered in revitalizing the region\u27s business community. This article provides another perspective. It reports upon the views held by a sample of Wisconsin business executives concerning the nature of the business environment in 1995. Specifically, this paper reports on the perceptions held by 24 executives (mostly vice presidents of planning or marketing) from Wisconsin corporations. Because vice-presidents of planning and marketing are most responsible for translating environmental trends into strategic actions, we believe their vision of the general business climate in 1995 will be of keen interest to those concerned about the future of Wisconsin\u27s economy

Sexting and Mental Health: A School-based Longitudinal Study Among Youth in Texas

Background: Sexting has emerged as a common socio-cultural problem in our society today. Few studies have estimated the prevalence of sexting among younger middle school youth and even fewer have assessed the relationship between sexting and mental health outcomes like anxiety and depression symptoms among middle school youth. Objectives: To estimate the prevalence of sexting among sixth and seventh-grade middle school students in a large urban school district in Southeast Texas and to assess its relationship with mental health outcomes (both anxiety and depression) among these youth. Methods: A retrospective analysis of an existing three-year randomized, two-arm, nested longitudinal study was conducted. Associations between sexting and depression symptoms; and sexting and anxiety symptoms were assessed via univariate and multivariate logistic analysis. Results: The prevalence of sexting among sixth graders was found to be 12%. Compared to youth who were not engaged in sexting, engagement in sexting was associated with significantly increased odds of depression and anxiety symptoms. Conclusion: Sexting is common among youth and is associated with poorer mental health outcomes such as anxiety and depression among these youth, but further validation of these findings is needed

UV Imaging Polarimetry of the Seyfert 2 Galaxy Mrk 3

We present UV imaging polarimetry data of the Seyfert 2 galaxy Mrk 3 taken by the Hubble Space Telescope. The polarized flux is found to be extended to ~1 kpc from the nucleus, and the position angles of polarization are centrosymmetric, confirming that the polarization is caused by scattering. We determine the location of the hidden nucleus as the center of this centrosymmetric pattern. From the polarization images taken in two broad bands, we have obtained the color distribution of the polarized flux. Some regions have blue polarized flux, consistent with optically-thin dust scattering, but some bright knots have a color similar to that of Seyfert 1 nucleus. Also, the recent Chandra X-ray observation suggests that the ratio of scattered UV flux to scattered X-ray flux is rather similar to the intrinsic UV/X-ray ratio in a Seyfert 1 nucleus, if the observed extended X-ray continuum is scattered light. While the scattered X-ray would be essentially from electron scattering, the UV slope and UV/X-ray ratio both being similar to Seyfert 1's would lead to two possibilities as to the nature of the UV scatterers. One is that the UV may also be scattered by electrons, in which case the scattering gas is somehow dust-free. The other is that the UV is scattered by dust grains, but the wavelength-independent UV scattering with low efficiency indicated by the UV slope and UV/X-ray ratio would suggest that the grains reside in UV-opaque clouds, or the dust might be mainly composed of large grains and lacks small-grain population.Comment: 15 pages, 8 figures (plus 2 color versions of grayscale figures), To appear in ApJ; minor corrections for the proofs of the manuscrip

Sexual health education for behavior change: How much is enough?

Purpose: Successful implementation of sexual health curricula in school settings is often compromised by competing academic priorities. This study explores the association between exposure to sexual health lessons (time-on-task in hours and lesson content topics) and delayed sexual initiation of middle school students at long term follow-up. Methods: Post hoc data analysis was conducted from a RCT (n=15 middle schools) in the south-central U.S. in which grade 7 students demonstrated delayed sexual initiation (adjusted odds ratio [AOR]: 1.54, 95% CI: 1.20 to 1.99) by grade 9 follow-up after using It’s Your Game (IYG), a 24 lesson sexual health curriculum. Logistic regression was conducted on a sub-sample of 314 grade 7 and 8 students who received IYG and who were sexually inexperienced at baseline, adjusting for covariates of age, gender, and race/ethnicity to address the impact of lesson exposure variables (time-on-task in hours and type of sexual health content) on initiation of any sex by grade 9. Results: The greatest impact of exposure on delayed sexual initiation was a duration of 13 or more lesson hours (OR = 8.40; p\u3c0.05) and exposure to lesson content on HIV/STI and pregnancy consequences (OR = 4.93; p\u3c0.05). Conclusions: Results support previous exposure studies and provide guidance on how effective sexual health curricula can meet the challenges of delivery in a reduced and competitive academic environment

Hippocampus and retrosplenial cortex combine path integration signals for successful navigation

The current study used fMRI in humans to examine goal-directed navigation in an open field environment. We designed a task that required participants to encode survey-level spatial information and subsequently navigate to a goal location in either first person, third person, or survey perspectives. Critically, no distinguishing landmarks or goal location markers were present in the environment, thereby requiring participants to rely on path integration mechanisms for successful navigation. We focused our analysis on mechanisms related to navigation and mechanisms tracking linear distance to the goal location. Successful navigation required translation of encoded survey-level map information for orientation and implementation of a planned route to the goal. Our results demonstrate that successful first and third person navigation trials recruited the anterior hippocampus more than trials when the goal location was not successfully reached. When examining only successful trials, the retrosplenial and posterior parietal cortices were recruited for goal-directed navigation in both first person and third person perspectives. Unique to first person perspective navigation, the hippocampus was recruited to path integrate self-motion cues with location computations toward the goal location. Last, our results demonstrate that the hippocampus supports goal-directed navigation by actively tracking proximity to the goal throughout navigation. When using path integration mechanisms in first person and third person perspective navigation, the posterior hippocampus was more strongly recruited as participants approach the goal. These findings provide critical insight into the neural mechanisms by which we are able to use map-level representations of our environment to reach our navigational goals

Real-space investigation of short-range magnetic correlations in fluoride pyrochlores NaCaCo2_2F7_7 and NaSrCo2_2F7_7 with magnetic pair distribution function analysis

We present time-of-flight neutron total scattering and polarized neutron scattering measurements of the magnetically frustrated compounds NaCaCo$_2$F$_7$ and NaSrCo$_2$F$_7$, which belong to a class of recently discovered pyrochlore compounds based on transition metals and fluorine. The magnetic pair distribution function (mPDF) technique is used to analyze and model the total scattering data in real space. We find that a previously-proposed model of short-range XY-like correlations with a length scale of 10-15 \AA, combined with nearest-neighbor collinear antiferromagnetic correlations, accurately describes the mPDF data at low temperature, confirming the magnetic ground state in these materials. This model is further verified by the polarized neutron scattering data. From an analysis of the temperature dependence of the mPDF and polarized neutron scattering data, we find that short-range correlations persist on the nearest-neighbor length scale up to 200 K, approximately two orders of magnitude higher than the spin freezing temperatures of these compounds. These results highlight the opportunity presented by these new pyrochlore compounds to study the effects of geometric frustration at relatively high temperatures, while also advancing the mPDF technique and providing a novel opportunity to investigate a genuinely short-range-ordered magnetic ground state directly in real space

Effect of Preanalytical Processing of ThinPrep Specimens on Detection of High-Risk Human Papillomavirus by the Aptima HPV Assay

Two important preanalytical protocols performed on liquid-based cytological specimens, namely, automated cytology processing and glacial acetic acid (GAA) treatment, may occur prior to the arrival of specimens in a molecular diagnostics laboratory. Ninety-two ThinPrep vials previously positive for high-risk human papillomavirus (HPV) via the Cervista HPV HR test were preselected and alternated with 92 previously negative ThinPrep vials. The specimen set was processed in a consecutive fashion by an automated cytology processor without fastidious decontamination precautions. Carryover potential was subsequently assessed by performance of the Aptima HPV assay on aliquots from reprocessed ThinPrep vials. All previously negative ThinPrep vials yielded a negative result following routine automated cytology processing, despite close proximity to known-positive ThinPrep vials. In separate experiments, aliquots from 236 ThinPrep vials were forwarded for tandem analysis with and without GAA treatment. Data from GAA- and mock-treated specimens generated by Aptima HPV were compared to correlate data generated by Cervista. A 99.2% concordance of Aptima HPV results from GAA-treated and mock-treated specimens was noted. This result differed from the concordance result derived from Cervista (91.5%; P \u3c 0.0002). Of the initially positive Cervista results, 21.9% reverted to negative following GAA treatment; the correlate value was 2.7% for Aptima HPV (P = 0.01). While deleterious effects of GAA treatment on genomic DNA were noted with Cervista (P = 0.0015), GAA treatment had no significant effects on Aptima HPV specimen signal/cutoff ratios or amplification of internal control RNA (P ≥ 0.07). The validity of an Aptima HPV result is independent of GAA treatment and routine automated cytology processing

Higher Education

Non

Engineering spin squeezing in a 3D optical lattice with interacting spin-orbit-coupled fermions

One of the most important tasks in modern quantum science is to coherently control and entangle many-body systems, and to subsequently use these systems to realize powerful quantum technologies such as quantum-enhanced sensors. However, many-body entangled states are difficult to prepare and preserve since internal dynamics and external noise rapidly degrade any useful entanglement. Here, we introduce a protocol that counterintuitively exploits inhomogeneities, a typical source of dephasing in a many-body system, in combination with interactions to generate metrologically useful and robust many-body entangled states. Motivated by current limitations in state-of-the-art three-dimensional (3D) optical lattice clocks (OLCs) operating at quantum degeneracy, we use local interactions in a Hubbard model with spin-orbit coupling to achieve a spin-locking effect. In addition to prolonging inter-particle spin coherence, spin-locking transforms the dephasing effect of spin-orbit coupling into a collective spin-squeezing process that can be further enhanced by applying a modulated drive. Our protocol is fully compatible with state-of-the-art 3D OLC interrogation schemes and may be used to improve their sensitivity, which is currently limited by the intrinsic quantum noise of independent atoms. We demonstrate that even with realistic experimental imperfections, our protocol may generate $\sim10$--$14$ dB of spin squeezing in $\sim1$ second with $\sim10^2$--$10^4$ atoms. This capability allows OLCs to enter a new era of quantum enhanced sensing using correlated quantum states of driven non-equilibrium systems.Comment: 20 pages, 12 figure

The variability of warm absorbers in Active Galactic Nuclei

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 2006.Includes bibliographical references (p. 171-184).This thesis presents three studies of warm (photoionized) absorber variability in Active Galactic Nuclei (AGN) using high-resolution X-ray spectra provided by the Chandra High Energy Transmission Grating (HETG). The first study is a single observation of the AGN MR 2251-178, which is known to have a highly variable warm absorber (WA). We find an unusually thin effective hydrogen column density along the line of sight compared to previous observations. Strong line emission without corresponding absorption indicates significant WA geometric structure. Strong absorption features in the spectrum are evidence of a highly-ionized, high-velocity outflow, which could be carrying a large amount of mass and energy out of the AGN. In the second study, we search for absorption lines variability in the well-studied WA of MCG -6-30-15. We find a significant anti-correlation over time between at least two ions, with suggestions of additional time variation in other ions. At least one line, the is - 2p resonance line of Mg XII, varies as a function of 2-10 keV continuum luminosity. Luminosity-driven ionization changes alone are insufficient to explain the observed variation.(cont.) Either multiple factors influence line strength on observable time scales, or the line of sight to the central source varies over time through a structured absorber. In the third study, we survey spectra from the HETG data archive. We model the normalized excess variance (NEV) spectrum of a varying WA and find that it does not explain high-energy (> 2 keV) spectral variation, nor does it generally fit NEV spectra at lower energies (< 2 keV). We also search through each spectrum at high resolution (AA = 0.01 A) for bins which vary more than expected due to normal Poissonian fluctuations. We find some evidence for such variation in the aggregate sample, though not in AGN individually. Our results show that WA structure is more complicated than pictured in contemporary models. Future high-resolution spectroscopic variability studies are certainly warranted. AGN models should eventually consider the effects of WA structure and the influence of continuum variation on the WA.by Robert R. Gibson.Ph.D