21 research outputs found
Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs
Prednisona e meloxicam no tratamento de ratos submetidos ao trauma agudo da medula espinhal
Recuperação funcional de cães com doença do disco intervertebral toracolombar submetidos ao tratamento cirúrgico
Diferentes tempos de eletroestimulação neuromuscular (eenm) de média frequência (kotz) em cães
TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord
Myelopathy associated with cervical epidural spinal metastasis of follicular-compact thyroid carcinoma in two dogs
This case report describes the clinical, histopathological and immunohistochemical findings in two dogs with myelopathy associated with metastasis of follicular-compact thyroid carcinoma. Microscopically, both primary neoplasms were characterized by polygonal cells arranged in follicles (occasionally filled with eosinophilic colloid-like material) or in sheets. The neoplastic cells had a moderately eosinophilic cytoplasm and there was moderate anisokaryosis and anisocytosis. Additionally, the neoplastic cells were positive for thyroglobulin on immunohistochemistry, confirming the follicular origin of both tumors. This is a very uncommon presentation of this pathological condition
Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease
Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation
Mielopatia compressiva por lipoma de células fusiformes infiltrativo em cão Compressive myelopathy by infiltrative spindle cell lipoma in a dog
Relata-se um caso de lipoma de células fusiformes infiltrativo diagnosticado em cadela com sinais neurológicos de ataxia proprioceptiva, reação postural ausente no membro pélvico direito, paraparesia fracamente ambulatória e dor à palpação sobre as vértebras torácicas craniais. A mielografia demonstrou compressão extradural do lado direito sobre a quinta vértebra torácica. À necropsia foi observado neoplasma que invadia o canal vertebral na quarta e quinta vértebras torácicas com compressão acentuada da medula espinhal. Microscopicamente, foram observados adipócitos neoplásicos bem diferenciados, com áreas de células fusiformes, diagnosticado como lipoma de células fusiformes infiltrativo. A avaliação por imuno-histoquímica, com anticorpo anti-CD34, revelou positividade principalmente nas áreas fusiformes do lipoma.A female dog was referred presenting neurological signs of proprioceptive ataxy, proprioceptive deficit in the right pelvic limb, mild ambulatory paresis and spinal pain during the palpation in thoracic vertebrae. It was observed a right extradural compression of spinal cord over fourth and fifth thoracic vertebrae by spinal myelography. During necropsy evaluation, it was observed a neoplasm which infiltrated in the spinal canal in the fourth and fifth thoracic vertebrae with marked compression of the spinal cord. Microscopically there were well differentiated neoplasic adipocytes, with areas of spindle cells, diagnosed as infiltrative spindle cell lipoma. The immunohistochemical staining revealed positive CD34 cells mainly in the areas of spindle cells lipoma