Aquaculture in the Baltic Sea area – A concept for joint research of Baltic Sea abutters

A concept for joint research on aquaculture in the Baltic Sea area is presented. It consists of three major parts, the promotion of an aquaculture-based-fisheries, the development of low-output land-based aquaculture systems, and the search for sustainably produced substances from aquatic organisms to be used for different processes. They include substitutes for feeding stuffs or products of importance for medical, biotechnological and industrial applications

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study

Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is currently hampered by the lack of accurate and early biomarkers for diagnosis of AKI and the evaluation of the severity of the disease. In 2010, we established a multivariate peptide marker pattern consisting of 20 naturally occurring urinary peptides to screen patients for early signs of renal failure. The current study now aims to evaluate if, in a different study population and potentially various AKI causes, AKI can be detected early and accurately by proteome analysis. Methods Urine samples from 60 patients who developed AKI after cardiac surgery were analyzed by capillary electrophoresis-mass spectrometry (CE-MS). The obtained peptide profiles were screened by the AKI peptide marker panel for early signs of AKI. Accuracy of the proteomic model in this patient collective was compared to that based on urinary neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) ELISA levels. Sixty patients who did not develop AKI served as negative controls. Results From the 120 patients, 110 were successfully analyzed by CE-MS (59 with AKI, 51 controls). Application of the AKI panel demonstrated an AUC in receiver operating characteristics (ROC) analysis of 0.81 (95 % confidence interval: 0.72–0.88). Compared to the proteomic model, ROC analysis revealed poorer classification accuracy of NGAL and KIM-1 with the respective AUC values being outside the statistical significant range (0.63 for NGAL and 0.57 for KIM-1)

Nahrungs- und Futtermittel in der Fischaufzucht

Die Erfindung betrifft ein Nahrungs- oder Futtermittel mit einer Beimengung von Phytohaemagglutinin und/oder von wenigstens einer Isoform einer Phytohaemagglutinin-Untereinheit, insbesondere die Verwendung von Phytohaemagglutinin als Fischfutterzusatz in kommerziellen Brutfuttern zur Unterstützung der Reifung des Verdauungstraktes und damit zur Steigerung der larvalen Verdauungseffizienz. Des Weiteren betrifft sie die Verwendung von Phytohaemagglutinin zur Einsparung von Lebendfutter in der Fischzucht

Influence of salinity and cadmium on the volume of Pacific herring eggs

Changes in total volume and volume of the yolk and perivitelline space of Pacific herring eggs were examined throughout incubation at 5°C in relation to salinity of the incubation medium (5, 20, 35‰ S), and after exposure to cadmium (0.05–10 ppm Cd) at 20‰ S. After fertilization and filling of the perivitelline space there was a decline in total egg volume in all salinities until 60–80 hr after fertilization. There followed a period of relative stability of total volume (100–240 hr), then a slow decline until hatching (240–618 hr). There was an inverse relation, between egg volume and salinity at all stages of egg development. Eggs transferred from 20‰ to 5 or 35‰ S, 87.4 hr after fertilization (90% blastodermal overgrowth of the yolk), showed only minor changes in total egg volume within the period of relative stability (100–240 hr). Prior to 80 hr, changes in egg volume appeared primarily to be simpleadjustments to prevailing osmotic and ionic conditions, modified, however, by presumed irreversible changes induced in the egg in relation to salinity experience at, and shortly after, fertilization. Subsequently, between 80–100 hr, egg volume appears to becomeregulated, commencing in the interval between late blastodermal overgrowth and blastopore closure. Yolk volume declined after fertilization, reached a minimum 40–60 hr after fertilization, increased to 100 hr, then decreased in the period of relative stability of total volume — presumably in relation to rapid growth of the embryo. In the latter period, yolk volume appeared resistant to change when eggs are transferred from 20 ‰ to 5 or 35 ‰ S, 87.4 hr, after fertilization. Volume of the perivitelline space reached a maximum after fertilization, then decreased until about 100 hr; between 100 and 240 hr it increased rapidly and was influenced only in a minor way by salinity changes in the incubation medium 87.4 hr after fertilization. Eggs exposed to cadmium in the interval between 1/2 and 30 hr after fertilization showed major reductions in total egg volume; total volume in the period of relative stability (100–240 hr) was much reduced and normal volume was not recovered after removal of such eggs to uncontaminated water at 30 hr