20 research outputs found
Longitudinal Inflammation, Cognitive Decline, and Alzheimerâs Disease: A Mini-Review
The role of inflammation in cognitive decline has generated considerable interest, although few longitudinal evaluations have been conducted. A review of the literature yields mixed findings, but suggests that inflammatory dysregulation is evident and may be related to clinical outcomes. The directionality, magnitude, and progression of these associations remain unclear. Future studies employing multiple time points of inflammatory data along with Alzheimerâs disease biomarkers are critical for explication of longitudinal inflammation in cognitive decline