15,659 research outputs found
The Effect of Expansion on Mass Entrainment and Stability of Super-Alfv\'enic Jets
We extend investigations of mass entrainment by jets, which previously have
focused on cylindrical supermagnetosonic jets and expanding trans-Alfv\'enic
jets, to a set of expanding supermagnetosonic jets. We precess these jets at
the origin to excite the helical mode of the Kelvin-Helmholtz (or KH)
instability, in order to compare the results with predictions from linear
stability analysis. We analyze this simulation set for the spatial development
of magnetized mass, which we interpret as jet plus entrained, initially
unmagnetized external mass. As with the previous simulation sets, we find that
the growth of magnetized mass is associated with the growth of the KH
instability through linear, nonlinear, and saturated stages and with the
expansion of magnetized material in simulated observations of the jet. From
comparison of measured wavelengths and wave speeds with the predictions from
linear stability analysis, we see evidence that the KH instability is the
primary cause for mass entrainment in these simulations, and that the expansion
reduces the rate of mass entrainment. This reduced rate can be observed as a
somewhat greater distance between the two transition points separating the
three stages of expansion.Comment: 18 pages, 6 figures, AASTeX, to appear in Nov 1 issue of ApJ (vol
543), postscript versions of Figures 3 and 5 are available at
http://crux.astr.ua.edu/~rosen/supcon/rh.htm
Interstitial gas and density-segregation in vertically-vibrated granular media
We report experimental studies of the effect of interstitial gas on
mass-density-segregation in a vertically-vibrated mixture of equal-sized bronze
and glass spheres. Sufficiently strong vibration in the presence of
interstitial gas induces vertical segregation into sharply separated bronze and
glass layers. We find that the segregated steady state (i.e., bronze or glass
layer on top) is a sensitive function of gas pressure and viscosity, as well as
vibration frequency and amplitude. In particular, we identify distinct regimes
of behavior that characterize the change from bronze-on-top to glass-on-top
steady-state.Comment: 4 pages, 5 figures, submitted to PRL; accepted in PRE as rapid
communication, with revised text and reference
Modeling the functional genomics of autism using human neurons.
Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation, making them highly useful adjuncts to animal models. Here, we examined whether a human neuronal culture system could be utilized to assess the transcriptional program involved in human neural differentiation and to model some of the molecular features of a neurodevelopmental disorder, such as autism. Primary normal human neuronal progenitors (NHNPs) were differentiated into a post-mitotic neuronal state through addition of specific growth factors and whole-genome gene expression was examined throughout a time course of neuronal differentiation. After 4 weeks of differentiation, a significant number of genes associated with autism spectrum disorders (ASDs) are either induced or repressed. This includes the ASD susceptibility gene neurexin 1, which showed a distinct pattern from neurexin 3 in vitro, and which we validated in vivo in fetal human brain. Using weighted gene co-expression network analysis, we visualized the network structure of transcriptional regulation, demonstrating via this unbiased analysis that a significant number of ASD candidate genes are coordinately regulated during the differentiation process. As NHNPs are genetically tractable and manipulable, they can be used to study both the effects of mutations in multiple ASD candidate genes on neuronal differentiation and gene expression in combination with the effects of potential therapeutic molecules. These data also provide a step towards better understanding of the signaling pathways disrupted in ASD
Vortex ratchet reversal: The role of interstitial vortices
Triangular arrays of Ni nanotriangles embedded in superconducting Nb films
exhibit unexpected dynamical vortex effects. Collective pinning with a vortex
lattice configuration different from the expected fundamental triangular
"Abrikosov state" is found. The vortex motion which prevails against the
triangular periodic potential is produced by channelling effects between
triangles. Interstitial vortices coexisting with pinned vortices in this
asymmetric potential, lead to ratchet reversal, i.e. a DC output voltage which
changes sign with the amplitude of an applied alternating drive current. In
this landscape, ratchet reversal is always observed at all magnetic fields (all
numbers of vortices) and at different temperatures. The ratchet reversal is
unambiguously connected to the presence of two locations for the vortices:
interstitial and above the artificial pinning sites.Comment: 21 pages, 4 figures, 1 Tabl
Development of temporal auditory processing in childhood: Changes in efficiency rather than temporal-modulation selectivity
The ability to detect amplitude modulation (AM) is essential to distinguish the spectro-temporal
features of speech from those of a competing masker. Previous work shows that AM sensitivity
improves until 10 years of age. This may relate to the development of sensory factors (tuning of
AM filters, susceptibility to AM masking) or to changes in processing efficiency (reduction in internal noise, optimization of decision strategies). To disentangle these hypotheses, three groups of
children (5–11 years) and one of young adults completed psychophysical tasks measuring thresholds for detecting sinusoidal AM (with a rate of 4, 8, or 32 Hz) applied to carriers whose inherent
modulations exerted different amounts of AM masking. Results showed that between 5 and 11
years, AM detection thresholds improved and that susceptibility to AM masking slightly increased.
However, the effects of AM rate and carrier were not associated with age, suggesting that sensory
factors are mature by 5 years. Subsequent modelling indicated that reducing internal noise by a factor 10 accounted for the observed developmental trends. Finally, children’s consonant identification
thresholds in noise related to some extent to AM sensitivity. Increased efficiency in AM detection
may support better use of temporal information in speech during childhood
Functional correlates of optic flow motion processing in Parkinson’s disease
The visual input created by the relative motion between an individual and the environment, also called optic flow, influences the sense of self-motion, postural orientation, veering of gait, and visuospatial cognition. An optic flow network comprising visual motion areas V6, V3A, and MT+, as well as visuo-vestibular areas including posterior insula vestibular cortex (PIVC) and cingulate sulcus visual area (CSv), has been described as uniquely selective for parsing egomotion depth cues in humans. Individuals with Parkinson’s disease (PD) have known behavioral deficits in optic flow perception and visuospatial cognition compared to age- and education-matched control adults (MC). The present study used functional magnetic resonance imaging (fMRI) to investigate neural correlates related to impaired optic flow perception in PD. We conducted fMRI on 40 non-demented participants (23 PD and 17 MC) during passive viewing of simulated optic flow motion and random motion. We hypothesized that compared to the MC group, PD participants would show abnormal neural activity in regions comprising this optic flow network. MC participants showed robust activation across all regions in the optic flow network, consistent with studies in young adults, suggesting intact optic flow perception at the neural level in healthy aging. PD participants showed diminished activity compared to MC particularly within visual motion area MT+ and the visuo-vestibular region CSv. Further, activation in visuo-vestibular region CSv was associated with disease severity. These findings suggest that behavioral reports of impaired optic flow perception and visuospatial performance may be a result of impaired neural processing within visual motion and visuo-vestibular regions in PD.Published versio
Mutual learning in a tree parity machine and its application to cryptography
Mutual learning of a pair of tree parity machines with continuous and
discrete weight vectors is studied analytically. The analysis is based on a
mapping procedure that maps the mutual learning in tree parity machines onto
mutual learning in noisy perceptrons. The stationary solution of the mutual
learning in the case of continuous tree parity machines depends on the learning
rate where a phase transition from partial to full synchronization is observed.
In the discrete case the learning process is based on a finite increment and a
full synchronized state is achieved in a finite number of steps. The
synchronization of discrete parity machines is introduced in order to construct
an ephemeral key-exchange protocol. The dynamic learning of a third tree parity
machine (an attacker) that tries to imitate one of the two machines while the
two still update their weight vectors is also analyzed. In particular, the
synchronization times of the naive attacker and the flipping attacker recently
introduced in [1] are analyzed. All analytical results are found to be in good
agreement with simulation results
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