Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry.

Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium. Our data suggest that the release of Pbl/Ect2 from the nucleus at mitotic entry drives Rho-dependent activation of Myosin-II and, in parallel, induces a switch from Arp2/3 to Diaphanous-mediated cortical actin nucleation that depends on Cdc42, aPKC, and Par6. At the same time, the mitotic relocalization of these apical protein complexes to more lateral cell surfaces enables Cdc42/aPKC/Par6 to take on a mitosis-specific function-aiding the assembly of a relatively isotropic metaphase cortex. Together, these data reveal how the repolarization and remodeling of the actomyosin cortex are coordinated upon entry into mitosis to provide cells with the isotropic and rigid form they need to undergo faithful chromosome segregation and division in a crowded tissue environment

Plan de clase de la unidad de óptica reflexión y refracción

Debido a los altos índices de estudiantes que reprueban la materia Física D, se ha decidido realizar un plan piloto para implementar un plan de estudio que incluya el cambio de metodología para el dictado de esta materia. La metodología a seguir está basada en el método de Gagne, ya que este pone énfasis en el aprendizaje para lograr el desarrollo individual y promueve el desarrollo de habilidades más complejas en el individuo. El método de Gagne se fundamenta en la teoría del procesamiento de la información, que se refiere a la secuencia de procesos y operaciones mentales que se realizan para llegar a un conocimiento organizado de grandes cantidades de información. Las variables que interfieren en la aplicación de este método son: 1. Los procesos de aprendizaje 2. Las fases del aprendizaje 3. Los resultados del aprendizaje 4. Las condiciones del aprendizaj

Electric properties of granitic rocks

The objective of this work is to clarify the role of water content on the charge trans- port mechanisms of different granitic rocks. The mineralogical content of the rocks will also be taken into account. From the electrical point of view these materials are rather insulating porous media where charge injection creates different phenomena like build-up charges, space charge limited currents, surface effects and other behav- iors that resemble much a variety of oxides, like AlO

Avaliação de genótipos de soja submetidos ao encharcamento.

Levando-se em consideração a grande variedade de cultivares no mercado e também os impactos das mudanças climáticas sobre a produção agrícola, torna-se necessário a seleção dos genótipos de soja adaptados ao alagamento imediato dos solos e também aqueles que melhor se recuperam após este estresse. Assim, o objetivo deste trabalho foi avaliar o comportamento de genótipos de soja quando submetidos a período de encharcamento do solo. O ensaio foi conduzido na safra 2008/09 na Granja Quatro Irmãos (Município de Rio Grande), no delineamento de blocos ao acaso, com quatro repetições, sendo a parcela composta por quatro linhas com 5 m de comprimento e 0,50 m de espaçamento entre linhas, sendo descartadas as duas linhas externas e 50 cm na extremidade de cada linha. Os genótipos avaliados foram: BRS 255 RR,BMX Apolo RR e FUNDACEP 53 RR (ciclo precoce); BRS 244 RR, BRS 246 RR e BRS Taura RR (ciclo médio);BRS Pampa RR, CD 219 RR e FUNDACEP 59 RR (ciclo tardio). Dentre os genótipos de ciclo precoce o que apresentou a menor perda para rendimentos de grãos quando submetido ao encharcamento foi Fundacep 53 RR, dentre os de ciclo médio foi BRS 246 RR. Na avaliação dos genótipos de ciclo tardio observou-se que na média durante o encharcamento no reprodutivo eles foram mais produtivos que os genótipos de ciclo precoce e médio

Distribution of Complex and Core Lipids within New Hyperthermophilic Members of the Archaea Domain

Core and complex lipids of several new hyperthermophilic archaeal isolates were analyzed. The organisms belong to the Sulfolobales,Archaeoglobus, Pyrobaculum, and Methanococcus. A detailed structural investigation of complex lipids of Pyrobaculum species is reported. The different lipid structures are of help for a rapid and simple phylogenetic classification of the new isolates. They are in agreement with the classification based on other features

Massive vector fields on the Schwarzschild spacetime: quasinormal modes and bound states

We study the propagation of a massive vector or Proca field on the Schwarzschild spacetime. The field equations are reduced to a one-dimensional wave equation for the odd-parity part of the field and two coupled equations for the even-parity part of the field. We use numerical techniques based on solving (scalar or matrix-valued) three-term recurrence relations to compute the spectra of both quasi-normal modes and quasi-bound states, which have no massless analogue, complemented in the latter case by a forward-integration method. We study the radial equations analytically in both the near-horizon and far-field regions and use a matching procedure to compute the associated spectra in the small-mass limit. Finally, we comment on extending our results to the Kerr geometry and its phenomenological relevance for hidden photons arising e.g. in string theory compactifications.Comment: 15 pages, 8 figures; minor corrections, to be published in Phys. Rev.

Application of the S=1 underscreened Anderson lattice model to Kondo uranium and neptunium compounds

Magnetic properties of uranium and neptunium compounds showing the coexistence of Kondo screening effect and ferromagnetic order are investigated within the Anderson lattice Hamiltonian with a two-fold degenerate $f$-level in each site, corresponding to $5f^2$ electronic configuration with $S=1$ spins. A derivation of the Schrieffer-Wolff transformation is presented and the resulting Hamiltonian has an effective $f$-band term, in addition to the regular exchange Kondo interaction between the $S=1$ $f$-spins and the $s=1/2$ spins of the conduction electrons. The obtained effective Kondo lattice model can describe both the Kondo regime and a weak delocalization of $5f$-electron. Within this model we compute the Kondo and Curie temperatures as a function of model parameters, namely the Kondo exchange interaction constant $J_K$, the magnetic intersite exchange interaction $J_H$ and the effective $f$-bandwidth. We deduce, therefore, a phase diagram of the model which yields the coexistence of Kondo effect and ferromagnetic ordering and also accounts for the pressure dependence of the Curie temperature of uranium compounds such as UTe.Comment: 9 pages, 4 figure

Low Temperature metamagnetism and Hall effect anomaly in Kondo compound CeAgBi2

Heavy fermion (HF) materials exhibit a rich array of phenomena due to the strong Kondo coupling between their localized moments and itinerant electrons. A central question in their study is to understand the interplay between magnetic order and charge transport, and its role in stabilizing new quantum phases of matter. Particularly promising in this regard is a family of tetragonal intermetallic compounds Ce{$TX$}$_2$ ($T=$ transition metal, $X=$ pnictogen), that includes a variety of HF compounds showing $T$-linear electronic specific heat $\bf{C_e \sim \gamma T}$, with $\gamma\sim$ 20-500 mJ$\cdot$mol$^{-1}$~K$^{-2}$, reflecting an effective mass enhancement ranging from small to modest. Here, we study the low-temperature field-tuned phase diagram of high-quality CeAgBi$_2$ using magnetometry and transport measurements. We find an antiferromagnetic transition at ${T_{N} = 6.4}$~K with weak magnetic anisotropy and the easy axis along the $c$-axis, similar to previous reports (${T_{N} = 6.1}$~K). This scenario, along with the presence of two anisotropic Ruderman-Kittel-Kasuya-Yosida (RKKY) interactions, leads to a rich field-tuned magnetic phase diagram, consisting of five metamagnetic transitions of both first and second order. In addition, we unveil an anomalous Hall contribution for fields $H<54$ kOe which is drastically altered when $H$ is tuned through a trio of transitions at 57, 78, and 84~kOe, suggesting that the Fermi surface is reconstructed in a subset of the metamagnetic transitions.Comment: (*equal contribution