(2-Chloro­benzo[h]quinolin-3-yl)methanol

In the title mol­ecule, C14H10ClNO, all non-H atoms are coplanar (r.m.s deviation = 0.0266 Å). In the crystal, symmetry-related mol­ecules are hydrogen bonded via inter­molecular O—H⋯O inter­actions, forming chains along the b axis

Ethyl 2,6-dichloro-4-phenyl­quinoline-3-carboxyl­ate

In the title compound, C18H13Cl2NO2, the quinoline ring system is almost planar (r.m.s. deviation 0.009 Å), and the phenyl and carboxyl­ate planes are twisted away from it by 59.2 (1) and 65.9 (2)°, respectively

1-[(2-Chloro-3-quinolyl)methyl]indoline-2,3-dione

In the title compound, C18H11ClN2O2, the isatin and 2-chloro-3-methylquinoline units are both almost planar, with r.m.s. deviations of 0.0075 and 0.0086 Å, respectively, and the dihedral angle between the mean planes of the two units is 83.13 (7)°. In the crystal, a weak intermolecular C—H... O interaction links the molecules into chains along the c axis

Antidiabetic Studies of Dihydropyrimido[4,5-a]acridin-2-amines

An in vitro antidiabetic activity on -amylase and -glucosidase activity of novel 10-chloro-4-(2-chlorophenyl)-12-phenyl-5,6-dihydropyrimido[4,5-a]acridin-2-amines (3a-3f) were evaluated. Structures of the synthesized molecules were studied by FT-IR, 1 H NMR, 13 C NMR, EI-MS, and single crystal X-ray structural analysis data. An in silico molecular docking was performed on synthesized molecules (3a-3f). Overall studies indicate that compound 3e is a promising compound leading to the development of selective inhibition of -amylase and -glucosidase