4 research outputs found
The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry
Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes
Assessing the influence of soil abiotic and biotic factors on Nostoc commune inoculation success
The management of patients with venous thromboembolism in Italy: insights from the PREFER in VTE registry
Venous thromboembolism (VTE) is the third most common cardiovascular disease. Real-life data on the clinical presentation, risk factors, diagnosis, and treatment of VTE in Italy and Europe are required to optimize the management of this disease. The PREFER in VTE registry, a prospective non-interventional real-life study, was designed to assess clinical characteristics and management of patients with VTE, use of health care resources, and on-treatment patient quality of life. Eligible consecutive patients with objectively diagnosed VTE were enrolled in the registry and followed up for 12 months. Between January and December 2013, 816 Italian and 1027 patients from 6 European countries other than Italy (European patients) were enrolled in the registry, and followed up until December 2014. Italian patients were the oldest (mean age 65.7 years) among the European patients. The Italian patients with a history of cancer were 24.6 % of whom 63.2 % had an active cancer (18.2 and 57.0 %, respectively, in Europe). Parenteral heparin was given, as initial treatment, in 73.8 % of Italian patients (66.4 % in Europe); VKA in combination with other treatments in 45.8 % (34.7 % in Europe); and VKA as the only anticoagulant treatment in 24.4 % (17.2 % in Europe). Of the Italian patients, 43.2 and 90.6 % of patients were hospitalized for deep vein thrombosis and pulmonary embolism, respectively; 65.4 % were admitted to the hospital through the emergency department. Following a real world approach, PREFER in VTE shows that the Italian patients, among and compared to the European patients, are the oldest, have a history of cancer more commonly, receive an initial treatment with heparin more commonly, and are more commonly hospitalized, particularly if affected by PE
Tratamientos Psicológicos Empíricamente Apoyados Para la Infancia y Adolescencia: : Estado de la Cuestión
Background: The empirical
evidence accumulated on the effi cacy, effectiveness, and effi ciency of
psychotherapeutic treatments in children and adolescents calls for an
update. The main goal of this paper objective was to carry out a selective
review of empirically supported psychological treatments for a variety
of common psychological disorders and problems in childhood and
adolescence. Method: A review was carried out of the psychological
treatments for different psychological disorders and problems in socialemotional or behavioral adjustment in the child-adolescent population
according to the Spanish National Health System (Clinical Practice
Guidelines) levels of evidence and degrees of recommendation. Results:
The fi ndings suggest that psychological treatments have empirical
support for addressing a wide range of psychological problems in these
developmental stages. The degree of empirical support ranges from low
to high depending on the phenomenon analyzed. The review suggests
unequal progress in the different fi elds of intervention. Conclusions:
From this update, psychologists will be able to make informed decisions
when implementing those empirically supported treatments to address the
problems that occur in childhood and adolescence.Antecedentes: la evidencia empírica acumulada en los últimos años sobre
la efi cacia, efectividad y efi ciencia de los tratamientos psicológicos en la
infancia y adolescencia reclama una actualización. El principal objetivo
de este artículo es el de llevar a cabo una revisión de los tratamientos
psicológicos empíricamente apoyados para una diversidad de problemas
psicológicos habituales en la infancia y la adolescencia. Método:
se revisan los tratamientos psicológicos para diferentes trastornos
psicológicos y problemas en el ajuste socioemocional o conductual en
población infanto-juvenil en función de los niveles de evidencia y grados
de recomendación del Sistema Nacional de Salud de España (Guías de
Práctica Clínica). Resultados: los hallazgos sugieren que los tratamientos
psicológicos específi camente dirigidos a niños, niñas y adolescentes
disponen de apoyo empírico para el abordaje de un amplio elenco de
problemas psicológicos. Este grado de apoyo empírico oscila de bajo a
alto en función del problema analizado. La revisión muestra un avance
desigual en los diferentes campos de intervención. Conclusiones: a partir
de esta actualización, los profesionales de la psicología podrán tomar
decisiones informadas a la hora de implementar aquellas intervenciones
psicológicas con apoyo empírico para el abordaje de los problemas en la
infancia y la adolescenci