Dimensões formacionais para uma gestão colegiada: experiências (auto)biográficas de coordenadores(as) do curso de pedagogia

This article aims to reflect on the praxis of Pedagogical Coordination developed in the Pedagogy course at a public university. The memories are organized in the political, pedagogical and technical dimensions of training reported by coordinators from the perspective of (auto)biographical narrative research as a theoretical-methodological investigation. The results presented contribute to understanding the importance of the training dimension of management, strengthening the history of the institution and revealing new management practices that influence the training of teachers. The conclusion we reached was that assuming the role of coordinator demands knowledge that, sometimes, the teacher has not yet built and this causes doubts and anxieties in the work that must be developed. Furthermore, the collaboration of peers is essential for carrying out a training process committed to the emancipation of subjects, building paths for initial and in-service training based on training principles that consider the concrete reality for carrying out the work. In this training experience, we built a dialogic, fair, dignified and solidary movement that was responsible for redefining paths, with a view to improving the decision-making process, amid the dialectic of contradictions and curricular and training issues that permeate management.Este artículo tiene como objetivo reflexionar sobre la praxis de la Coordinación Pedagógica desarrollada en la carrera de Pedagogía en una universidad pública. Las memorias se organizan en las dimensiones política, pedagógica y técnica de la formación relatada por los coordinadores desde la perspectiva de la investigación narrativa (auto)biográfica como investigación teórico-metodológica. Los resultados presentados contribuyen a comprender la importancia de la dimensión formativa de la gestión, fortaleciendo la historia de la institución y revelando nuevas prácticas de gestión que inciden en la formación de los docentes. La conclusión a la que llegamos fue que asumir el rol de coordinador exige conocimientos que, en ocasiones, el docente aún no ha construido y esto provoca dudas y angustias en el trabajo que debe desarrollar. Además, la colaboración de los pares es fundamental para llevar a cabo un proceso formativo comprometido con la emancipación de los sujetos, construyendo caminos de formación inicial y en servicio basados ​​en principios formativos que consideren la realidad concreta para el desempeño del trabajo. En esta experiencia formativa construimos un movimiento dialógico, justo, digno y solidario que se encargó de redefinir caminos, con miras a mejorar la toma de decisiones, en medio de la dialéctica de contradicciones y cuestiones curriculares y formativas que permean la gestión.Este artigo objetiva refletir sobre a práxis da Coordenação Pedagógica desenvolvida no curso de Pedagogia em uma Universidade pública. As memórias são organizadas nas dimensões política, pedagógica e técnica da formação, relatadas por coordenadores/as, na perspectiva da pesquisa narrativa (auto)biográfica como investigação teórico-metodológica. Os resultados apresentados contribuem para entender a importância da dimensão formacional da gestão, fortalecer a história da instituição e revelar novas práticas de gestão que influenciam na formação de professores/as. A conclusão a qual chegamos foi que assumir a função de coordenador/a demanda um conhecimento que, por vezes, o/a docente ainda não construiu e isso provoca dúvidas e anseios no trabalho que deve ser desenvolvido. Ademais, a colaboração dos pares é fundamental para a realização de um processo formativo comprometido com a emancipação dos sujeitos, construindo caminhos para uma formação inicial e em serviço amparadas nos princípios formativos que consideram a realidade concreta para a realização do trabalho. Nesta experiência formativa, construímos um movimento dialógico, justo, digno e solidário que foi responsável pela redefinição de caminhos, com vistas a melhoria do processo de tomada de decisões, em meio a dialética das contradições e questões curriculares e formativas que perpassam a gestão

Glomerulopatia por IgA com crescentes fibrocelulares e associada à psoríase

Alguns estudos têm demonstrado uma ligação entre glomerulonefrite por IgA e psoríase e/ou uso de drogas anti-TNF. Descrevemos o caso de um paciente com artrite psoriática, em uso de anti-TNF por quatro anos, que apresentou nefropatia por IgA agravada por crescentes na biópsia renal e insuficiência renal necessitando de hemodiálise. Após a realização de terapia com metilprednisolona IV e três meses de corticoide oral, houve melhora significativa na função renal e proteinúria. O tratamento de diálise foi interrompido e tratamentos com SGLT-2 inibidores foram iniciados

Mycobacterium haemophilum: Emerging or Underdiagnosed in Brazil?

Fleury Ctr Diagnost Med, Microbiol Sect, BR-04344070 Sao Paulo, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilOswaldo Cruz Hosp, Sao Paulo, BrazilAlbert Einstein Hosp, Sao Paulo, BrazilSirio Libanes Hosp, Sao Paulo, BrazilServidores Estado Hosp, Rio De Janeiro, BrazilAlianca Hosp, Salvador, BA, BrazilLamina Lab, Rio De Janeiro, BrazilInst Oswaldo Cruz, BR-20001 Rio De Janeiro, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilWeb of Scienc

Evaluation of three recombinant proteins for the development of ELISA and immunochromatographic tests for visceral leishmaniasis serodiagnosis.

BACKGROUND Visceral Leishmaniasis (VL) is an infectious disease that is a significant cause of death among infants aged under 1 year and the elderly in Brazil. Serodiagnosis is a mainstay of VL elimination programs; however, it has significant limitations due to low accuracy. OBJECTIVE This study aimed to evaluate three recombinant Leishmania infantum proteins (rFc, rC9, and rA2) selected from previous proteomics and genomics analyses to develop enzyme-linked immunosorbent assay (ELISA) and immunochromatographic tests (ICT) for the serodiagnosis of human VL (HVL) and canine VL (CVL). METHODS A total of 186 human (70 L. infantum-infected symptomatic, 20 other disease-infected, and 96 healthy) and 185 canine (82 L. infantum-infected symptomatic, 27 L. infantum-infected asymptomatic, and 76 healthy) sera samples were used for antibody detection. FINDINGS Of the three proteins, rA2 (91.5% sensitivity and 87% specificity) and rC9 (95.7% sensitivity and 87.5% specificity) displayed the best performance in ELISA-HVL and ELISA-CVL, respectively. ICT-rA2 also displayed the best performance for HVL diagnosis (92.3% sensitivity and 88.0% specificity) and had high concordance with immunofluorescence antibody tests (IFAT), ELISA-rK39, IT-LEISH?, and ELISAEXT. ICT-rFc, ICT-rC9, and ICT-rA2 had sensitivities of 88.6%, 86.5%, and 87.0%, respectively, with specificity values of 84.0%, 92.0%, and 100%, respectively for CVL diagnosis. MAIN CONCLUSIONS The three antigens selected by us are promising candidates for VL diagnosis regardless of the test format, although the antigen combinations and test parameters may warrant further optimisation

Influence of hypoandrogenism in skin wound healing resistance in rats

Objective: The objective of the present study is to verify the effect of testosterone depletion on healing of surgical skin wounds at different ages and postoperative times. Methods: Forty-four Wistar male rats were divided into four groups: Group 1y (n = 11) – young control, sham-operated rats (30 days-old); Group 1A (n = 10) – adult control, sham-operated rats (three to four months old); Group 2Y (n = 10) – young rats after bilateral orchiectomy; and Group 2A (n = 11) – adult rats after bilateral orchiectomy. After six months, a linear incision was performed on the dorsal region of the animals. The resistance of the wound healing was measured in a skin fragment with a tensiometer, on the 7th and 21st postoperative days. Rresults: The wound healing resistance was higher in Group 1Y than in Group 2Y after seven days (p < 0.05). Wound healing resistance at 21 days was higher than at seven days in all groups (p < 0.05). Late wound healing resistance was not different between young and adult rats. Cconclusions: Bilateral orchiectomy decreased the wound healing resistance only in young animals at the seventh postoperative day

Morphological, metabolic and functional repercussions after orchiectomy in rats

Objective: To study the modifications in lipid profile, blood glucose and pressure, and morphological aspects of the adrenal gland in animals with hypogonadism secondary to total bilateral epididymectomy and orchiectomy. Methods: Young and adult male Wistar rats were distributed into the following groups: Group 1 – control, animals submitted only to scrotal incision and suture. Group 2 – animals submitted to total bilateral epididymectomy and orchiectomy. After these operations, studies were carried out to analyze possible repercussions of hypogonadism. In Study A, serum levels of free testosterone were measured, along with the body weight and cortical thickness of the adrenal gland of 30 adult rats. In Study B, serum values of glucose, triglycerides, total cholesterol, and HDL, LDL and VLDL fractions were measured in 20 young rats and 10 adult rats. In Study C, pressure of the caudal artery was measured by plethysmography in 24 adult animals. Rresults: Total bilateral epididymectomy and orchiectomy reduced serum levels of testosterone regardless of the age of the animal, and apparently does not modify macro- or microscopically the morphology of the adrenal gland. Hypogonadism secondary to total bilateral epididymectomy and orchiectomy did not modify the serum values of glucose, total cholesterol, LDL and HDL fractions. However, orchiectomy reduced the blood levels of triglycerides and VLDL cholesterol when performed in young rats. Testosterone deficiency was related to smaller weight gain and increased arterial pressure. Cconclusions: Castration reduces blood levels of triglycerides and VLDL cholesterol in young rats. In adult animals, it increases arterial pressure and is related to smaller weight gain

DESENVOLVIMENTO INICIAL DA CULTURA DA CANA-DE-AÇÚCAR SUBMETIDA A ESTRESSE LUMINOSO

A cana-de-a&ccedil;&uacute;car (Saccharum spp.) &eacute; uma esp&eacute;cie pertencente &agrave; Fam&iacute;lia Poaceae, importante para o cultivo comercial em diferentes partes do mundo. O presente trabalho teve como objetivo avaliar o desenvolvimento inicial da cultura da cana-de-a&ccedil;&uacute;car submetida a estresse luminoso. O experimento foi conduzido no Campus Experimental de Dracena da Universidade Estadual Paulista &ldquo;J&uacute;lio de Mesquita Filho&rdquo;, localizada em Dracena, Estado de S&atilde;o Paulo, no per&iacute;odo de mar&ccedil;o a abril de 2013, em Casa de Vegeta&ccedil;&atilde;o. O delineamento foi inteiramente casualizado com dois tratamentos e quinze repeti&ccedil;&otilde;es. Os tratamentos foram: intensidade luminosa 100% e intensidade luminosa 50%. Aos 30 dias ap&oacute;s o plantio foi avaliado o di&acirc;metro dos vasos xilem&aacute;ticos (DX); o di&acirc;metro dos vasos floem&aacute;ticos (DF); a espessura da epiderme da face superior ou adaxial (EAD); a espessura da epiderme da face inferior ou abaxial (EAB) e o di&acirc;metro das c&eacute;lulas da bainha do feixe (DCB). Tamb&eacute;m pela ocasi&atilde;o na colheita, foi avaliado o peso de mat&eacute;ria seca das ra&iacute;zes; peso de mat&eacute;ria seca da parte a&eacute;rea; n&uacute;mero de folhas; n&uacute;mero de perfilhos; di&acirc;metro de colmos; altura de planta; &aacute;rea foliar e condut&acirc;ncia estom&aacute;tica determinada pelo aparelho Por&ocirc;metro Modelo AP-4. O estresse luminoso influenciou as caracter&iacute;sticas: di&acirc;metro de xilema, espessura da epiderme abaxial, di&acirc;metro das c&eacute;lulas da bainha, peso de mat&eacute;ria seca, numero de folhas, n&uacute;mero de perfilhos, altura de planta e condut&acirc;ncia estom&aacute;tica