Concert recording 2017-05-01a

[Track 1]. Sonata in C major, Hob:XVI:50. I. Allegro II. Adagio III. Allegro molto / Franz Joseph Haydn -- [Track 2]. Ballades, op. 10, no. 1 in D minor Andante [Track 3]. No. 2, in D major Andante [Track 4]. No. 3, in B minor, Intermezzo-Allegro [Track 5]. No. 4, in B major, Andante con moto / Johannes Brahms -- [Track 6]. Etudes Tableaux. op. 33, n. 8 [Track 7]. op. 39, no. 1 [Track 8]. op. 39, n. 5 / Sergei Rachmaninoff -- [Track 9]. 3 encores for piano. I. Drops II. Streams III. Swells / Jose Mora-Jimenez

Concert recording 2015-04-29b

[Track 01]. Chaconne / Tomaso Antonio Vitali -- [Track 02]. Thème original varié, op. 15 / Henryk Wieniawski -- [Track 03]. Violin sonata no. 3, op. 108. Allegro ; Adagio ; Un poco e con sentiment ; Presto agitato / Johannes Brahms -- [Track 04]. Cantabile for violin and piano / Niccoló Paganini

Concert recording 2014-11-15

[Track 01]. Sonata for violin and piano, no. 3 / Ludwig van Beethoven -- [Track 02]. Sonata for violin and piano, no. 4 / Ludwig van Beethoven -- [Track 03]. Violin concerto in E minor. Allegro molto appassionato / Felix Mendelssohn -- [Track 04]. Violin concerto in A minor. Allegro ma non troppo /Antonín Dvořák -- [Track 05]. Five pieces for two violins / Dmitri Shostakovich

Concert recording 2016-11-16

[Tracks 1-3]. Concerto in E minor / Antonio Vivaldi -- [Tracks 4-5]. Sonata in F minor / Georg Philipp Telemann -- [Tracks 6-7]. Three etudes / José Siqueira -- [Track 8]. Andante e rondo ongarese / Carl Maria v. Weber -- [Track 9]. Monolog for bassoon / Isang Yun -- [Track 10]. Malevos / Noelia Escalzo

Concert recording 2017-04-23a

[Track 1]. From Rêverie. Sognai / Francesco Schira -- [Track 2]. Êtude-Tableau op. 39, no. 5 / Sergi Rachmaninoff -- [Track 3]. Capriccio / Rodney Newton -- [Track 4]. Solo de pajarillo / Omar Acosta -- [Track 5]. Butterflies and bobcats / David L. McIntyre -- [Track 6]. Song to the mother / Johannes Möller -- [Track 7]. Concerto for bass trombone. III. James Brown in the twilight zone / Chris Brubeck

Strong Carbon Features and a Red Early Color in the Underluminous Type Ia SN 2022xkq

We present optical, infrared, ultraviolet, and radio observations of SN 2022xkq, an underluminous fast-declining type Ia supernova (SN Ia) in NGC 1784 ($\mathrm{D}\approx31$ Mpc), from $<1$ to 180 days after explosion. The high-cadence observations of SN 2022xkq, a photometrically transitional and spectroscopically 91bg-like SN Ia, cover the first days and weeks following explosion which are critical to distinguishing between explosion scenarios. The early light curve of SN 2022xkq has a red early color and exhibits a flux excess which is more prominent in redder bands; this is the first time such a feature has been seen in a transitional/91bg-like SN Ia. We also present 92 optical and 19 near-infrared (NIR) spectra, beginning 0.4 days after explosion in the optical and 2.6 days after explosion in the NIR. SN 2022xkq exhibits a long-lived C I 1.0693 $\mu$m feature which persists until 5 days post-maximum. We also detect C II $\lambda$6580 in the pre-maximum optical spectra. These lines are evidence for unburnt carbon that is difficult to reconcile with the double detonation of a sub-Chandrasekhar mass white dwarf. No existing explosion model can fully explain the photometric and spectroscopic dataset of SN 2022xkq, but the considerable breadth of the observations is ideal for furthering our understanding of the processes which produce faint SNe Ia.Comment: 38 pages, 16 figures, accepted for publication in ApJ, the figure 15 input models and synthetic spectra are now available at https://zenodo.org/record/837925

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Outcomes of Severe Sepsis and Septic Shock Patients on Chronic Antiplatelet Treatment: A Historical Cohort Study

Background. Sepsis is characterized by dysfunctional activation of platelets, and antiplatelet therapy could improve the outcomes of septic patients. Methods. We performed a retrospective cohort study of severe sepsis or septic shock adult patients. Outcomes of patients on antiplatelet therapy were compared to those that were not taking antiplatelet therapy by univariate analysis followed by a propensity score analysis based on the probability of receiving antiplatelet therapy. Results. Of 651 patients included in the study 272 (42.8%) were on antiplatelet therapy before the development of severe sepsis or septic shock. After adjusting for important confounding variables antiplatelet therapy was not associated with a decreased risk of hospital mortality (odds ratio 0.73, 95% confidence interval 0.46-1.16). Antiplatelet therapy was associated with a decreased incidence of acute respiratory distress syndrome/acute lung injury (odds ratio 0.50, 95% confidence interval 0.35-0.71) and reduced need of mechanical ventilation (odds ratio 0.62, 95% confidence interval 0.45-87). Incidence of acute kidney injury was similar between both groups (odds ratio 1.08, 95% confidence interval 0.73-1.59). Conclusions. The use of antiplatelet therapy before the diagnosis of severe sepsis or septic shock was not associated with decreased hospital mortality. Antiplatelet therapy was associated with a decreased incidence of acute lung injury/acute respiratory distress syndrome