Exploring demand for forestry in Lake Victoria Basin (Western Kenya): An econometric approach

This paper determines the demand for a forestry program amongst rural households in western Kenya. It is based on a field survey with 277 households, using a stratified random sampling approach. The study follows attribute based method to elicit farmers’ preferences. Demand is measured in terms of additional number of trees that a household is willing to plant under different price schedules, including direct economic incentive to plant new seedlings. The mean willingness to plant new trees per household increases from 44 trees when farmers have to pay 10ksh/seedling, to 244 trees when farmers receive a payment of 10ksh/seedling. The paper uses fixed effects, random effects and random effect tobit models to estimate relevant parameters. Hausman specification test is returned insignificant, while implies that random effects specification is not incorrect. Price of seedlings (negative effect), availability of timber species (positive effect), gender of the respondent (men likely to plant more trees than women), and availability of agricultural labor at the household (positive) were all found to be significant. Increase in price of a seedling by 1Ksh reduced demand by nine seedlings, while addition of an adult who works full-time on the family farm will raise the demand for seedlings by 18. Furthermore, farmers in Yala River basin were likely to plant more trees than those in the Nyando River basin.Kenya, Lake Victoria, demand, tree seedlings, attribute based method, Demand and Price Analysis, Resource /Energy Economics and Policy, C23, Q23, Q57,

Social as much as environmental: the drivers of tree biomass in smallholder forest landscape restoration programmes

A major challenge for forest landscape restoration initiatives is the lack of quantitative evidence on how social factors drive environmental outcomes. Here we conduct an interdisciplinary quantitative analysis of the environmental and social drivers of tree biomass accumulation across 639 smallholder farms restoring native tree species in Mexico, Uganda and Mozambique. We use environmental and social data to assess the relative effects of key hypothesised drivers on aboveground biomass accumulation at the farm-level over ten years. We supplement this with a qualitative analysis of perspectives from local farmers and agroforestry technicians on the potential causal mechanisms of the observed social effects. We find that the material wellbeing of farmers (e.g. assets) and access to agroforestry knowledge explain as much variation in biomass as water availability. Local perspectives suggest that this is caused by the higher adaptive capacity of some farmers and their associated ability to respond to social-ecological shocks and stresses. Additionally, the variation in biomass between farms increased over time. Local perspectives suggested that this was caused by emergent exogenous and stochastic influences which cannot be reliably predicted in technical analyses and guidance. To deal with this persistent uncertainty, local perspectives emphasised the need for flexible and adaptive processes at the farm- and village-levels. The consistency of these findings across three countries suggests these findings are relevant to similar forest restoration interventions. Our findings provide novel quantitative evidence of a social-ecological pathway where the adaptive capacity of local land users can improve ecological processes. Our findings emphasize the need for forest restoration programmes to prioritise investment in the capabilities of local land users, and to ensure that rules support, rather than hinder, adaptive management

A Rare Manifestation of Cysticercosis Infestation

There are many causes of urticaria, which may vary from infections to malignancy. Among the infections, infestations by cysticercosis (larval stage of the tapeworm called Taenia solium) is an important cause. The present report is of forty four years old female who presented with urticaria and swelling on face. The swelling was later diagnosed as cysticercosis by noninvasive ultrasonography. The urticaria subsided after the treatment of cysticercosis. We report this case for rarity of its presentation. Key words: cysticercosis, chronic urticaria, Taenia solium, ultrasonograph

Application of Handheld Tele-ECG for Health Care Delivery in Rural India

Telemonitoring is a medical practice that involves remotely monitoring patients who are not at the same location as the health care provider. The purpose of our study was to use handheld tele-electrocardiogram (ECG) developed by Bhabha Atomic Research Center (BARC) to identify heart conditions in the rural underserved population where the doctor-patient ratio is low and access to health care is difficult. The objective of our study was clinical validation of handheld tele-ECG as a screening tool for evaluation of cardiac diseases in the rural population. ECG was obtained in 450 individuals (mean age 31.49 ± 20.058) residing in the periphery of Chandigarh, India, from April 2011 to March 2013, using the handheld tele-ECG machine. The data were then transmitted to physicians in Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, for their expert opinion. ECG was interpreted as normal in 70% individuals. Left ventricular hypertrophy (9.3%) was the commonest abnormality followed closely by old myocardial infarction (5.3%). Patient satisfaction was reported to be ~95%. Thus, it can be safely concluded that tele-ECG is a portable, cost-effective, and convenient tool for diagnosis and monitoring of heart diseases and thus improves quality and accessibility, especially in rural areas

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

Although the process of drug development requires efficacy and toxicity testing in animals prior to human testing, animal models have limited ability to accurately predict human responses to xenobiotics and other insults. Societal pressures are also focusing on reduction of and, ultimately, replacement of animal testing. However, a variety of in vitro models, explored over the last decade, have not been powerful enough to replace animal models. New initiatives sponsored by several US federal agencies seek to address this problem by funding the development of physiologically relevant human organ models on microscopic chips. The eventual goal is to simulate a human-on-a-chip, by interconnecting the organ models, thereby replacing animal testing in drug discovery and development. As part of this initiative, we aim to build a three-dimensional human liver chip that mimics the acinus, the smallest functional unit of the liver, including its oxygen gradient. Our liver-on-a-chip platform will deliver a microfluidic three-dimensional co-culture environment with stable synthetic and enzymatic function for at least 4 weeks. Sentinel cells that contain fluorescent biosensors will be integrated into the chip to provide multiplexed, real-time readouts of key liver functions and pathology. We are also developing a database to manage experimental data and harness external information to interpret the multimodal data and create a predictive platform

The Inflammatory Response to Double Stranded DNA in Endothelial Cells Is Mediated by NFκB and TNFα

Endothelial cells represent an important barrier between the intravascular compartment and extravascular tissues, and therefore serve as key sensors, communicators, and amplifiers of danger signals in innate immunity and inflammation. Double stranded DNA (dsDNA) released from damaged host cells during injury or introduced by pathogens during infection, has emerged as a potent danger signal. While the dsDNA-mediated immune response has been extensively studied in immune cells, little is known about the direct and indirect effects of dsDNA on the vascular endothelium. In this study we show that direct dsDNA stimulation of endothelial cells induces a potent proinflammatory response as demonstrated by increased expression of ICAM1, E-selectin and VCAM1, and enhanced leukocyte adhesion. This response was dependent on the stress kinases JNK and p38 MAPK, required the activation of proinflammatory transcription factors NFκB and IRF3, and triggered the robust secretion of TNFα for sustained secondary activation of the endothelium. DNA-induced TNFα secretion proved to be essential in vivo, as mice deficient in the TNF receptor were unable to mount an acute inflammatory response to dsDNA. Our findings suggest that the endothelium plays an active role in mediating dsDNA-induced inflammatory responses, and implicate its importance in establishing an acute inflammatory response to sterile injury or systemic infection, where host or pathogen derived dsDNA may serve as a danger signal.United States. Dept. of Defense (CDMRP Predoctoral Training Award)National Institutes of Health (U.S.) (NIH BioMEMS Resource Center Grant P41 EB-002503)National Institutes of Health (U.S.) (NIH Grant RO1AI063795)Shriners Hospital for Childre

Exploring demand for forestry in Lake Victoria Basin (Western Kenya): An econometric approach

This paper determines the demand for a forestry program amongst rural households in western Kenya. It is based on a field survey with 277 households, using a stratified random sampling approach. The study follows attribute based method to elicit farmers’ preferences. Demand is measured in terms of additional number of trees that a household is willing to plant under different price schedules, including direct economic incentive to plant new seedlings. The mean willingness to plant new trees per household increases from 44 trees when farmers have to pay 10ksh/seedling, to 244 trees when farmers receive a payment of 10ksh/seedling. The paper uses fixed effects, random effects and random effect tobit models to estimate relevant parameters. Hausman specification test is returned insignificant, while implies that random effects specification is not incorrect. Price of seedlings (negative effect), availability of timber species (positive effect), gender of the respondent (men likely to plant more trees than women), and availability of agricultural labor at the household (positive) were all found to be significant. Increase in price of a seedling by 1Ksh reduced demand by nine seedlings, while addition of an adult who works full-time on the family farm will raise the demand for seedlings by 18. Furthermore, farmers in Yala River basin were likely to plant more trees than those in the Nyando River basin

A comparison of granisetron and nitroglycerine for attenuating rocuronium pain: A double-blinded randomized, placebo controlled trial

Background: The incidence of pain reported in literature after IV administration of rocuronium is 50-80%. The aim of our study was to determine whether pre-treatment with intravenous granisetron and nitroglycerine would reduce rocuronium-induced pain. Methods: One hundred fifty patients of either sex, aged 18-65 years, American society of Anaesthesiologist grading (ASA) I-II, scheduled for various surgeries under general anesthesia were randomly assigned to one of the groups. Group G: received 2 granisetron (1mg/ml) diluted with 3 ml of 0.9% normal saline) while the Group C: received 5 ml of 0.9% normal saline. Group N: received 200΅g of nitroglycerine diluted to a total of 5 ml(with 0.9% normal saline). It was accompanied by manual venous occlusion for 20 seconds. Then 0.06mg/kg of rocuronium was injected through same cannula over 10-15 sec.Patients were asked by a blinded investigator to score the pain on injection of rocuronium using visual analogue scale (0-10) with 0-no pain,1-3 mild pain, 4-6 moderate and >=7 severe pain. At the same time discomfort in the form of patient′s movement, such as no movement (grade 0), movement only wrist (grade 1), movement to the upper arm and shoulder of injected arm (grade 2) or generalized movements (grade3) was observed. Statistical analysis using independent t test, Mann-Whitney test and reverse ANOVA was done. Results: 1. At 0 seconds, in group G number of patients who experienced withdrawl score of 0-1 were 92%,group N were 82% while only 26% of patients in group C had favourable withdrawl score.74% of patients in group C had score of 2-3 at same time. 2. At 0 sec, in group G number of patients who experienced VAS score of 0-3 were 96%, group N 72%. At same time Group C 48 % of patients had VAS score of 2-3. Conclusion: We conclude that pre-treatment with granisetron or nitroglycerine both are highly effective in attenuation of rocuronium induced pain

THE IMPACT OF LATERAL EPICONDYLITIS ON QUALITY OF LIFE

Background: Lateral epicondylitis is a work related disorder which is considered to be due to over-use or over-stress of the wrist extensors of the forearm. The patient suffers from pain and decreased function which affects the basic activities in daily life. This reduction in function leading to disability may affect the quality of life as it includes items related to self care, usual activities, emotional problems, pain etc. The present study was conducted to study the impact of Lateral epicondylitis on quality of life. Methods: 52 subjects diagnosed with Lateral epicondylitis were included in the study according to the inclusion and exclusion criteria. Outcome measures were: pain using Visual analog scale, functional disability using Patient rated tennis elbow evaluation and health-related quality of life using Short Form 36. Results: A significant positive correlation was found between pain and functional disability (p<.001). A significant negative correlation between pain and physical (p=.014) and mental (p=.052) component summary scores of quality of life was found. A significant negative correlation was found between functional disability and physical (p=.002) and mental (p=.015) component summary scores of quality of life. Also a significant correlation was found between physical and mental component summary scores of quality of life (p<.001). Conclusions: Significant correlation was seen between pain, functional disability and quality of life. This suggests that with an increase in severity of pain there is increase in functional disability with lower QOL both physically and mentally

Voluntary carbon trading: potential for community forestry projects in India

Voluntary carbon markets, such as the Chicago Climate Exchange (CCX), were worth $90 million in 2006. This paper finds that community forestry interventions of three organizations in India are eligible to sell carbon sequestration credits on CCX. Their combined annual sequestration potential is 104,427 tons of carbon dioxide (tCO2), worth$417,708 at 2007 prices. Although this value will be difficult to realize immediately, it indicates the potential for carbon sequestration to raise rural incomes in India. These benefits can be actualized by first linking small pilot projects with CCX and then scaling up operations. Projects will also need to reduce transaction costs to raise the shares of carbon revenue that farmers receive. The diversion of land to raise tree crops needs to be balanced with food security concerns. A potentially viable approach would be to take up carbon plantations on common lands with concerned agencies acting as a liaison between farmer groups and the market.India, CDM, Carbon markets, Community forestry, Chicago, Climate Exchange