COMPREHENSIVE REVIEW OF KRIMIGHNA DRUGS MENTIONED IN THE AYURVEDIC PHARMACOPOEIA OF INDIA

Ayurveda is the science of life having wide description of Krimighna dravya in its literature. Ayurvedic pharmacopeia of India published by the Ministry of AYUSH is a monograph of single drugs; which is very popular for all stack holder of Ayush system of medicines. This article details the review of single drugs mentioned in API part I (Vol I to VI) and their screening for Krimighna (antimicrobial) properties. Present article also aims for validating classical fact with published scientific research work. Authors searched 54 drugs out of 519 single drugs described in the API & it was found most of Ayurvedic Krimighnadravya were recognized for having antimicrobial property which was established through various Preclinical & clinical work carried out by the scientific community. Authors collected data with references to validate API drugs having antimicrobial property. All screened content can be taken for various high-tech research work by various students in MD, PhD or in the various other project of CSIR, DST, EMR project of CCRAS for further development of new drugs and conversion of available drugs to latest dosage form

VLSI and post-CMOS electronics: devices, circuits and interconnects

VLSI and Post-CMOS Electronics is a useful reference guide for researchers, engineers and advanced students working in the area of design and modelling of VLSI and post-CMOS devices and their circuits

VLSI and post-CMOS electronics: design, modelling and simulation

VLSI and Post-CMOS Electronics is a useful reference guide for researchers, engineers and advanced students working in the area of design and modelling of VLSI and post-CMOS devices and their circuits

Nanotechnological interventions in sustainable agriculture

1153-1158The major problems associated with agriculture are the sustainable management of natural resources. With technological innovations and capital investments crop production has increased but care of ecological systems has not been given priorities and thus created imbalance in the natural cycle of the soil, crop productivity, salinization, moisture content, organic matter and seeping problems of pesticides. Nanotechnology provides a plethora of techniques to face the challenges of increasing population and food production, at the same time taking care of the environment, and has opened new avenues for sustainable agriculture. It has a myriad of applications, whether it is in medicine, electronics, agriculture, food technology, environment, cosmetics. Worldwide, there is improvement in sensing which is highly important in agriculture. Crop yield mainly depends on soil fertility, water supply and other environmental factors. Nanotechnology has revolutionised food production commonly referred to as “green nanoagroscience” which implements green chemistry in an eco-friendly manner and using biocompatible methods, which is cost-effective. This review mainly focuses on the latest development in nanobiotechnology and their applications along with challenges in sustainable agriculture developmentand the future prospects

Modeling and Analysis of Cu-Carbon Nanotube Composites for Sub-Threshold Interconnects

The sub-threshold regime is suited for applications requiring ultra-low power consumption with low to medium frequency (tens to hundreds of MHz) of operation. Therefore, this paper presents electrical modeling and comprehensive analysis of copper-carbon nanotube (Cu-CNT) composite interconnects for sub-threshold circuit design. At lower operating frequencies, the effective complex conductivity of Cu-CNT composites in the nanoscale is formulated by developing an analytical model. Based on the proposed equivalent single conductor model, the frequency-dependent resistance and inductance of composite interconnects are computed. Finally, the sub-threshold crosstalk effect, transfer gain, and Nyquist stability of coupled Cu-CNT composite interconnect are analyzed using ABCD matrix approach

Secure Information System for Visitor Access Recognition using Machine Learning

Typical visitor access apps are usually passive/manual. The security guards in highly populated communities have to verify the identity of the visitors every single time, be it the residents or new people. This process is also time-consuming. Availability of the resident is also essential to approve the entry. VISITOR ACCESS is a better substitute for the regular visitor access systems. The process starts with choosing the house number and the name initially. When there is a known person, the visitor is verified, recognized, and approved to enter. If the visitor is unknown, he or she is asked to enter a few more details, which are sent to the resident’s mobile. A message is sent to the visitor’s mobile regarding the approval status to deal with the case of multiple visitors. Open CV is used to verify the identity of the visitors using face recognition, and the app acts as an interface between the users and the system

Experimental and DFT Studies on Cp*Co(III)-Catalyzed Selective C8-Olefination and Oxyarylation of Quinoline N-Oxides with Terminal Alkynes

Herein we report Cp*Co(III)-catalysed site-selective (C8)-H olefination and oxyarylation of quinoline N-oxides with terminal alkynes. The selectivity for C8-olefination and oxyarylation is sterically and electronically controlled. In case of quinoline N-oxides (unsubstituted at C2-position), only olefination product is obtained irrespective of the nature of alkynes. In contrast, majorly oxyarylation is observed when 2-substituted quinoline N-oxides are reacted with bulkier alkynes such as 9-ethynyl phenanthrene. However, alkynes with electron-withdrawing groups provided only olefination products with 2-substituted quinoline N-oxides also. The developed strategy allowed a facile functionalization of naturally derived quinoline N-oxides and terminal alkynes to deliver corresponding olefinated and oxyarylated products. In the developed protocol, the \u27N-O’ bond played a dual role i.e., as a traceless directing group and an oxygen atom source (in case of oxyarylation), which is confirmed by 18O-labeling and crossover experiments. In addition, control experiments, deuterium labeling experiments, KIE studies and DFT studies are performed to understand the mechanism and origin of selectivity for different substrates. DFT studies revealed that the alkyne addition into Co-C bond is the rate limiting step. The observed product selectivity is reproduced by DFT methods. Furthermore, the energy decomposition analysis is performed to understand the origin of selec-tivity

Demographic Profile Of The Patients Presenting To A Neuro-Ophthalmology Clinic Of A Tertiary Eye Care Centre

"To evaluate the clinical profile of neuro-ophthalmic disease in patients presenting to Neuro-ophthalmology clinic of a tertiary care centre during one year.