Adrenergic Myocarditis in Pheochromocytoma

The clinical presentation of pheochromocytoma is variable and many biochemical and imaging methods have been suggested to improve the diagnostic accuracy of what has been termed "the great masquerader". This case-report is of a middle-aged woman with a non-specific clinical presentation suggesting acute coronary syndrome or subacute myocarditis. Cardiovascular magnetic resonance (CMR) at presentation showed myocardial edema and intramyocardial late gadolinium enhancement (LGE). An adrenal mass was seen, which was confirmed as pheochromocytoma and surgically removed. Our case shows evidence for acute adrenergic myocarditis, with resolution of both the edema and the LGE after surgical excision

Разработка и исследование конструкции привода управляемого задерживающего устройства шароструйно-эжекторного бурового снаряда

В работе рассмотрены принципы шароструйного бурения, а так же устройство шаростуйно-эжекторного снаряда. Предложены варианты модернизации данного снаряда.In this paper, the principles of pellet impact drilling, as well as the construction of a pellet-ejector projectile, are considered. Variants of modernization of this projectile are offered

Computational fluid dynamics-based estimation of blood flow rate in Doppler analsys: in vivo validation by means of phase contrast magnetic resonance imaging

We carry out an in vivo validation of a new method for estimating blood flow rate from the maximum velocity, as it is usually done in single-wire Doppler catheter measurements. A common practice is to measure the centerline velocity and to recover the flow rate (a-priori approach) by exploiting an assumption on the shape of velocity profile, either a parabolic or a flat one. Our method proposes a new formula valid for the peak instant linking the maximum velocity and the flow rate including the Womersley number, in order to account in a more accurate way the haemodynamics conditions (Womersley-based approach). In vivo validation of the Womersley-based approach is performed. An experimental protocol using cine Phase Contrast MRI (2D PCMRI) technique has been designed and applied to ten healthy young volunteers in three different arterial districts: the abdominal aorta, the common carotid artery and the brachial artery. Each PCMRI dataset has been used twice. 1) To compute the value of the blood flow rate used as a gold standard. 2) To estimate the flow rate using information only on the maximum velocity and on the diameter value (i.e. emulating the intravascular Doppler data acquisition) by using the a priori and the Womersley-based approaches. All the in vivo results concerning the three arterial districts allow to state that the Womersley-based approach provides better estimates of the flow rate at the peak instant with the respect to the a-priori approach. These results might have relevant clinical implication, for example in Coronary Flow Reserve determination