Tentative Detection of the Rotation of Eris

We report a multi-week sequence of B-band photometric measurements of the dwarf planet Eris using the {\it Swift} satellite. The use of an observatory in low-Earth orbit provides better temporal sampling than is available with a ground-based telescope. We find no compelling evidence for an unusually slow rotation period of multiple days, as has been suggested previously. A $\sim$1.08 day rotation period is marginally detected at a modest level of statistical confidence ($\sim$97%). Analysis of the combination of the $Swift$ data with the ground-based B-band measurements of \citet{2007AJ....133...26R} returns the same period ($\sim$1.08 day) at a slightly higher statistical confidence ($\sim$99%).Comment: Accepted to Icarus 2008-Aug-19. 19 pages total, including 4 figures and 1 tabl

Discovery of Temperate Latitude Clouds on Titan

Until now, all the clouds imaged in Titan's troposphere have been found at far southern latitudes (60°-90° south). The occurrence and location of these clouds is thought to be the result of convection driven by the maximum annual solar heating of Titan's surface, which occurs at summer solstice (2002 October) in this south polar region. We report the first observations of a new recurring type of tropospheric cloud feature, confined narrowly to ~40° south latitude, which cannot be explained by this simple insolation hypothesis. We propose two classes of formation scenario, one linked to surface geography and the other to seasonally evolving circulation, which will be easily distinguished with continued observations over the next few years

A new 1.6-micron map of Titan’s surface

We present a new map of Titan's surface obtained in the spectral 'window' at ∼1.6 μm between strong methane absorption. This pre-Cassini view of Titan's surface was created from images obtained using adaptive optics on the W.M. Keck II telescope and is the highest resolution map yet made of Titan's surface. Numerous surface features down to the limits of the spatial resolution (∼200–300 km) are apparent. No features are easily identifiable in terms of their geologic origin, although several are likely craters

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

Poly(ADP-ribose) polymerase-1 (PARP-1) has become an important pharmacological target in the treatment of cancer due to its cellular role as a 'DNA-strand break sensor', which leads in part to resistance to some existing chemo- and radiological treatments. Inhibitors have now been developed which prevent PARP-1 from synthesizing poly(ADP-ribose) in response to DNA-breaks and potentiate the cytotoxicity of DNA damaging agents. However, with the recent discoveries of PARP-2, which has a similar DNA-damage dependent catalytic activity, and additional members containing the 'PARP catalytic' signature, the isoform selectivity and resultant pharmacological effects of existing inhibitors are brought into question. We present here the crystal structure of the catalytic fragment of murine PARP-2, at 2.8 A resolution, and compare this to the catalytic fragment of PARP-1, with an emphasis on providing a possible framework for rational drug design in order to develop future isoform-specific inhibitors

Real-time depth sectioning: Isolating the effect of stress on structure development in pressure-driven flow

Transient structure development at a specific distance from the channel wall in a pressure-driven flow is obtained from a set of real-time measurements that integrate contributions throughout the thickness of a rectangular channel. This “depth sectioning method” retains the advantages of pressure-driven flow while revealing flow-induced structures as a function of stress. The method is illustrated by applying it to isothermal shear-induced crystallization of an isotactic polypropylene using both synchrotron x-ray scattering and optical retardance. Real-time, depth-resolved information about the development of oriented precursors reveals features that cannot be extracted from ex-situ observation of the final morphology and that are obscured in the depth-averaged in-situ measurements. For example, at 137 °C and at the highest shear stress examined (65 kPa), oriented thread-like nuclei formed rapidly, saturated within the first 7 s of flow, developed significant crystalline overgrowth during flow and did not relax after cessation of shear. At lower stresses, threads formed later and increased at a slower rate. The depth sectioning method can be applied to the flow-induced structure development in diverse complex fluids, including block copolymers, colloidal systems, and liquid-crystalline polymers

Direct measurement of the size of 2003 UB313 from the Hubble Space Telescope

We have used the Hubble Space Telescope to directly measure the angular size of the large Kuiper belt object 2003 UB313. By carefully calibrating the point spread function of a nearby field star, we measure the size of 2003 UB313 to be 34.3$\pm$1.4 milliarcseconds, corresponding to a diameter of 2400$\pm$100 km or a size $\sim5$% larger than Pluto. The V band geometric albedo of 2003 UB313 is $86\pm7$%. The extremely high albedo is consistent with the frosty methane spectrum, the lack of red coloring, and the lack of observed photometric variation on the surface of 2003 UB313. Methane photolysis should quickly darken the surface of 2003 UB313, but continuous evaporation and redeposition of surface ices appears capable of maintaining the extreme alebdo of this body

The influence of regional feedbacks on circulation sensitivity

Weakening of the tropical overturning circulation in a warmer world is a robust feature in climate models. Here an idealized representation of ocean heat flux drives a Walker cell in an aquaplanet simulation. A goal of the study is to assess the influence of the Walker circulation on the magnitude and structure of climate feedbacks, as well as to global sensitivity. We compare two CO_2 perturbation experiments, one with and one without a Walker circulation, to isolate the differences attributable to tropical circulation and associated zonal asymmetries. For an imposed Walker circulation, the subtropical shortwave cloud feedback is reduced, which manifests as a weaker tropical-subtropical anomalous energy gradient and consequently a weaker slow down of the Hadley circulation, relative to the case without a Walker circulation. By focusing on the coupled feedback circulation system, these results offer insights into understanding changes in atmospheric circulation and hence the hydrological cycle under global warming

Lifshitz points in blends of AB and BC diblock copolymers

We consider micro- and macro-phase separation in blends of AB and BC flexible diblock copolymers. We show that, depending on architecture, a number of phase diagram topologies are possible. Microphase separation or macrophase separation can occur, and there are a variety of possible Lifshitz points. Because of the rich parameter space, Lifshitz points of multiple order are possible. We demonstrate Lifshitz points of first and second order, and argue that, in principle, up to 5th-order Lifshitz points are possible

Titan imagery with Keck adaptive optics during and after probe entry

We present adaptive optics data from the Keck telescope, taken while the Huygens probe descended through Titan's atmosphere and on the days following touchdown. No probe entry signal was detected. Our observations span a solar phase angle range from 0.05° up to 0.8°, with the Sun in the west. Contrary to expectations, the east side of Titan's stratosphere was usually brightest. Compiling images obtained with Keck and Gemini over the past few years reveals that the east-west asymmetry can be explained by a combination of the solar phase angle effect and an enhancement in the haze density on Titan's morning hemisphere. While stratospheric haze was prominent over the northern hemisphere, tropospheric haze dominated the south, from the south pole up to latitudes of ∼45°S. At 2.1 μm this haze forms a polar cap, while at 1.22 μm it appears in the form of a collar at 60°S. A few small clouds were usually present near the south pole, at altitudes of 30–40 km. Our narrowband J,H,K images of Titan's surface compare extremely well with that obtained by Cassini ISS, down to the small-scale features. The surface contrast between dark and bright areas may be larger at 2 μm than at 1.6 and 1.3 μm, which would imply that the dark areas may be covered by a coarser-grained frost than the bright regions and/or that there is additional 2 μm absorption there