36 research outputs found
Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort
- Author
- Abbas Zaigham
- Abdou Ahmed Mohamed Saleh
- Abou Rached Antoine
- Acalovschi Monica
- Afredj Nawel
- Ahlers Silke
- Ahmetagic Sead
- Ahn Sang Hoon
- Aissaoui Magda
- Akriviades Euaggelos
- Al Ghandoor Zuhal
- Al Gharabally Abeer
- Al Qameesh Jihad
- Alavian Seyed Moayed
- Alberto Sara
- Aleixo Maria Jo\ue3o
- Amedea Alessandri
- Amoroso Pietro
- Ancuta Ioan
- Andreica Vasile
- Andreoni Massimo
- Arama Victoria
- Ascione Antonio
- Askar Haifa
- Assene Collins
- Attili Adolfo Francesco
- Augustyniak Krystyna
- Baka Cwierz Barbara
- Bakalos Georgios
- Bandiera Franco
- Banyai Tivadar
- Basho Jovan
- Bassi Paolo
- Bastens Boris
- Bellantani Stefano
- Bellati Giorgio
- Berak Hanna
- Bevanda Milenko
- Bhalla Ajay
- Biglino Alberto
- Bocakova Jana
- Bourgeois Stefan
- Brixko Christian
- Brunetto Maurizia
- Bruno Savino
- Bunganic Ivan
- Calkic Lejla
- Caruntu Florin
- Casinelli Katia
- Castellacci Roberto
- Castelli Francesco
- Cattelan Anna Maria
- Chiriaco Piergiorgio
- Cijevschi Cristina
- Colletta Cosimo
- Colombo Massimo
- Colombo Silvia
- Coman Felicia
- Cool Mike
- Coppola Carmine
- Correa Maria Cassia
- Costa Chiara
- Craxi Antonio
- Curescu Manuela
- D'Amico Emilio
- D'Angelo Salvatore
- Daryani Nasser Ebrahimi
- De Galocsy Chantal
- Debzi Nabil
- Decaestecker Jochen
- Delic Dragan
- Delwaide Jean
- Demelia Luigi
- Derbala Moutaz
- Deron Zbigniew
- Di Giacomo Antonio
- Di Perri Giovanni
- Dimitroulopoulos Dimitrios
- Dohaibi Ahmad
- Drakoulis Christos
- Drenaggi Davide
- Elefsiniotis Ioannis
- Enyedi Judit
- Erne Elke
- Esmat Gamal
- Evgenidis Nikolaos
- Fabri Milotka
- Faria Telo
- Ferenci Peter
- Fernandes Julio Cesar
- Ferrari Carlo
- Ferraz Maria Lucia
- Fierbinteanu Braticevici Carmen
- Flisiak Robert
- Foster Graham R.
- Foti Giuseppe
- Francisci Daniela
- Fried Katalin
- Gabr Mamdouh
- Ganga Roberto
- George Christophe
- Gervain Judit
- Gheorghe Liana
- Giannoulis Grigoris
- Gietka Andrzej
- Giguere Alain
- Gomide Geisa
- Guerreiro Hor\ue1cio
- Guessab Nawal
- Halota Waldemar
- Han Sang Young
- Hanno Abdelfatah
- Harxhi Arjan
- Hashmi Zahid
- Hassanein Tarek
- Hausinger P\ue9ter
- Henrion Jean
- Holoman Jozef
- Horsmans Yves
- Hoste Paul
- Houmani Zaher
- Hunyady Bela
- Ibrahimpasic Nevzeta
- Ionita Radu Florentina
- Ivanovski Ljubomir
- Jablkowski Maciej
- Jankovic Goran
- Janssens Filip
- Jarcuska Peter
- Jesic Rada
- Joksimovic Nenad
- Junior Elson Martins
- Juriens Ir\ue8ne
- Kanatakis Stilianos
- Karagiannis Ioannis
- Karatapanis Stilianos
- Ketikoglou Ioannis
- Kim Yoonjun
- Konstantinovic Ljiljana
- Krkoska Dusan
- Kupcova Viera
- Lakner Lilla
- Langlet Philippe
- Lasser Luc
- Laukens Pierre
- Lawate Parimal
- Lee Yun Nah
- Lefebvre Veronique
- Lencu Monica
- Lengyel Gabriella
- Lesch Miklos
- Lipczynski Artur
- Livia Hara
- Luaia Rosang
- Lyra Andre
- Macedo Guilherme
- Mahindad Nadir
- Mahiou Hassene
- Makkai Erzs\ue9bet
- Malhado Jos\ue9
- Manesis Emmanuel
- Mangia Alessandra
- Manolakopoulos Spilios
- Mansinho Kamal
- Martinet Jean Paul
- Masood Siddiq
- Matarazzo Filippo
- Mazur Wlodzimierz
- Mazzella Giuseppe
- Mazzeo Maurizio
- Megna Angelo Salomone
- Mela Maria
- Mello Carlos Eduardo
- Memoli Massimo
- Memon Sadik
- Mendes Claudio
- Merat Shahin
- Mesihovic Rusmir
- Michielsen Peter
- Miftode Egidia
- Mimidis Konstantinos
- Mohsin Aftab
- Montalbano Marzia
- Montalto Giuseppe
- Monteverde Carlos
- Motoc Adriana
- Mousoulis Georgios
- Mulkay Jean Pierre
- Musat Marioara
- Musialik Joanna
- Nagorni Aleksandar
- Nagral Aabha
- Nagy Istvan
- Nassiri Toosi Mohsen
- Nemes\ue1nszky Elem\ue9r
- Nevens Frederik
- Nikolopoulou Vassiliki
- Nozic Darko
- Olszok Iwona
- Olteanu Dan
- Oltman Marian
- Omar Ashraf
- Orfanou Eleni
- Orlandini Alessandra
- Orszulak Grazyna
- Ozsv\ue1r Zs\uf3fia
- Paik Seung Woon
- Parikh Samir
- Pascu Oliviu
- Passariello Nicola
- Patai \uc1rp\ue1d
- Peixe Paula
- Pelemis Mijomir
- Pereira Patricia
- Philip Mathew
- Picciotto Antonio
- Piekarska Anna
- Piekos Tomasz
- Pieri Alessandro
- Pietrangelo Antonello
- Pigozzi Maria Graziella
- Pirisi Mario
- Preotescu Liliana
- Quirino Tiziana
- Racz Istvan
- Radowska Danuta
- Raimondo Giovanni
- Ramos Jos\ue9 Presa
- Rao Padaki
- Rapaccini Gian Ludovico
- Reddy K. Rajender
- Reynaert Hendrik
- Ribiczey P\ue1l
- Rizzardini Giuliano
- Rizzetto Mario
- Robaeys Geert
- Roxo Fausto
- Ruiz Fernando Jose
- Russello Maurizio
- Russo FRANCESCO PAOLO
- Sabusco Giuseppe
- Santantonio Teresa
- Saracco Giorgio Maria
- Sarmento Castro Rui
- Schneider Ferenc
- Schreter Ivan
- Schuller J\ue1nos
- Serejo F\ue1tima
- Servais Benoit
- Shabanaj Gentian
- Sharara Ala
- Shiffman Mitchell L.
- Sieklucki Jerzy
- Silaghi Rodica
- Silva Giovanni
- Silva Mariliza Henrique
- Simon Krzysztof
- Skladany Lubomir
- Soardo Giorgio
- Somani Sanjay
- Sood Ajit
- Spinzi Giancarlo
- Sporea Ioan
- Sprengers Dirk
- Stan Marioara
- Stanciu Carol
- Streinu Cercel Adrian
- Svorcan Petar
- Szalay Ferenc
- Szantova Maria
- Szentgy\uf6rgyi L\ue1szl\uf3
- Szlauer Bronislawa
- Tallarico Ludovico
- Teixeira Rosangela
- Todorovic Zoran
- Tolvaj Gyula
- Tornai Istvan
- Trifan Anca
- Tsianos Epameinondas
- Tundo Paolo
- Tusnadi Anna
- V\ue1czi Zsuzsanna
- Vafiadi Zoubouli Irini
- Valente Cristina
- Van Der Meersch Filip
- Van Vlierberghe Hans
- Varga Marta
- Varghese Rosh
- Varkonyi Istvan
- Velez Jorge
- Verhaz Antonija
- Verucchi Gabriella
- Vinci Maria
- Vincze Aron
- Vinelli Francesco
- Warakomska Iwona
- Warzee Philippe
- Yaghi Cesar
- Yang Jinmo
- Yousry Ayman
- Zaarour Fouad
- Zali Mohammad Reza
- Zignego Anna Linda
- Zuin Massimo
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND:
Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or discontinuations (sr-RD) and their impact on sustained virologic response (SVR) in patients receiving peginterferon alfa/ribavirin in routine practice.
METHODS:
A total of 3181 HCV-mono-infected treatment-naive patients were assigned to 24 or 48 weeks of peginterferon alfa/ribavirin by their physician. Patients were categorized by time-to-first sr-RD (Week 4/12). Detailed analyses of the impact of sr-RD on SVR24 (HCV RNA <50 IU/mL) were conducted in 951 Caucasian, noncirrhotic genotype (G)1 patients assigned to peginterferon alfa-2a/ribavirin for 48 weeks. The probability of SVR24 was identified by a baseline scoring system (range: 0-9 points) on which scores of 5 to 9 and <5 represent high and low probability of SVR24, respectively.
RESULTS:
SVR24 rates were 46.1% (754/1634), 77.1% (279/362), 68.0% (514/756), and 51.3% (203/396), respectively, in G1, 2, 3, and 4 patients. Overall, 16.9% and 21.8% patients experienced 651 sr-RD for peginterferon alfa and ribavirin, respectively. Among Caucasian noncirrhotic G1 patients: female sex, lower body mass index, pre-existing cardiovascular/pulmonary disease, and low hematological indices were prognostic factors of sr-RD; SVR24 was lower in patients with 651 vs. no sr-RD by Week 4 (37.9% vs. 54.4%; P = 0.0046) and Week 12 (41.7% vs. 55.3%; P = 0.0016); sr-RD by Week 4/12 significantly reduced SVR24 in patients with scores <5 but not 655.
CONCLUSIONS:
In conclusion, sr-RD to peginterferon alfa-2a/ribavirin significantly impacts on SVR24 rates in treatment-naive G1 noncirrhotic Caucasian patients. Baseline characteristics can help select patients with a high probability of SVR24 and a low probability of sr-RD with peginterferon alfa-2a/ribavirin
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
- Author
- A Kaldun Nossuli
- Aamir Jamal
- Adalbert Schiller
- Adam Cheifetz
- Adarsh Daswani
- Adeera Levin
- Adline Ghazi
- Adrian Guinsburg
- Adriana Cif
- Adriana Gabriela Onaca
- Adriana Ilavska
- Adriana Villarino
- Agarwal R.
- Agnieszka Starzec
- Ahmed Arif
- Ahmed Awad
- Aiping Yin
- Akimichi Asano
- Alan Jackson
- Alan McMahon
- Alan Perlman
- Alberto Di Carlo
- Alberto Esquenazi
- Alejandra Oviedo
- Alejandro Valdes Depeda
- Aleksandra Kendereski
- Alex Valenzuela
- Alexander Dreval
- Alexander Gonzalez
- Alexander Shinkov
- Alexander Turchin
- Alexandre Klein
- Alfonso Soto Gonzalez
- Alfred Penfornis
- Alfredo Chew Wong
- Alfredo Wassermann
- Ali Torshizi
- Alicia Chilito
- Alina Agafyina
- Alison Dawson
- Alva Hansraj
- Amer Al-Karadsheh
- Amorin Remus Popa
- Amrendra Kumar
- Amy Sprague
- Ana Limos
- Ana Maria Cusumano
- Ana Maria Elosegui
- Anabella Amigo
- Anatoliy Kazmirchuk
- Andrea Phillips
- Andrea Stella
- Andreas Maddux
- Andrej Dzupina
- Andres Alvarisqueta
- Andrew Johnson
- Andrew O'Shaughnessy
- Andrew Steele
- Andrian Yakov
- Andrzej Januszewicz
- Andrzej Madej
- Angelina Angelova
- Anibal Gastaldi
- Anil Gupta
- Anita Bhajan Manocha
- Anjanette Tan
- Anna Kaminska
- Anna Maria Veronelli
- Anna Strzelecka
- Anna Zateyshchikova
- Anselmo Bordonava
- Antanas Navickas
- Anthony Gunstone
- Anthony Roberts
- Antonio Ceriello
- Antonio Galan Serrano
- Antonio Scafuto Scotton
- Antonio Terrelonge
- Antônio Roberto Chacra
- Anupama Gowda
- Arjun D Sinha
- Armando Perez
- Ashot Mkrtumyan
- Atanas Koundurdjiev
- Augusto Vallejos
- Aurelian-Emil Ranetti
- Ayim Akyea-Djamson
- Aysha Badat
- Bakris G.
- Baldev Singh
- Barbara Greco
- Barbara Kaczmarek
- Barbara Rewerska
- Barry M Brenner
- Belia Martin Del Camp Blanco
- Bernard Zinman
- Bertrand Cariou
- Bertrand Dussol
- Bhasker Mehta
- Bhimavarapu Sudhakar
- Björn Paschen
- Bompoint S.
- Borys Mankovskyy
- Botond Csiky
- Boyan Nonchev
- Brenner B. M.
- Brett Kissela
- Brian Nichol
- Bruce Neal
- Bruce Trippe
- Bruno Geloneze Neto
- Bull S.
- Byung-Wan Lee
- C B Keshavamurthy
- Cannon C. P.
- Capuano G.
- Carlo Giorda
- Carlos Alberto Cuneo
- Carlos Arauz-Pacheco
- Carlos Barrera
- Carlos Perez
- Carmel Hawley
- Carmen Crisan
- Carol Pollock
- Carolyn Droste
- Caroucel Chuateco
- Caryl David
- Cecilia Garcia Ballesteros
- Cecilia Jimeno
- Celso Amodeo
- Cesar Javier Zaidman
- Cesar Yoiti Hayashida
- Chamberlain Obialo
- Chang-Hsun Hsieh
- Charles Cook
- Charles Kaupke
- Charytan D. M.
- Chek Loong Loh
- Chen Leia
- Cheol-Young Park
- Chih-Ching Lin
- Christopher P Cannon
- Christy Yao
- Chu P. -L.
- Chwen-Tzuei Chang
- Chye Lee Gan
- Clara Barrios
- Claude Galphin
- Claudia Goycoa
- Claudia Moreira de Brito
- Clodoaido Caringal
- Cristian Serafinceanu
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- Cynthia Christiano
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- Dalia Kozloviene
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- Daniel Weiner
- Daniil Chizhov
- Dariusz Sowinski
- Darren K McGuire
- Davesh Sennik
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- Dora Inés Molina de Salazar
- Dorota Mlodawska-Choluj
- Doru Negru
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- Edwards R.
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- Evgueniy Vazelov
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- Fayzal Ahmed
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- Fernanda Cristina Camelo Sanches
- Fernando Cereto Castro
- Fernando Flores Lozano
- Fernando Jimenez Florez
- Fernando Krynski
- Fernando M Edwin
- Fernando Thomé
- Fernando Trespalacios
- Florence Santos
- Florencia Kraft
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- Freemu Varghese
- Gabriela Cecilia Coloma
- Gabriela Genova-Hristova
- Gabriele von Ingersleben
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- Grazyna Popenda
- Greene T.
- Greg Fulcher
- Gregorio Obrador
- Gregorio Obrador Vera
- Grit Faulmann
- Guadalupe Morales Franco
- Guillermo Fragale
- Guixia Wang
- Gulam Latiff
- Gustavo Cristian Greloni
- Guy Chouinard
- Gyongyi Csecsei
- Gyorgy Paragh
- Halyna Tomashkevych
- Hans Prozesky
- Harpreet Bajaj
- Hasnain Khandwala
- Hector Rodriguez
- Heerspink H. J. L.
- Helena Oosthuizen
- Hendrik Nortje
- Henry Watson
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- Hernan Finkelstein
- Hernan Yupanqui
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- Hiralal Maheshwari
- Hiroko Oishi
- Hiromi Aoki
- Hiromi Rodriguez Pattzi
- Hiroshi Kono
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- Holly Wang
- Hong Mao
- Hong Zhang
- Hongguang Zheng
- Hongli Lin
- Horacio Sessa
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- Hyuk-Sang Kwon
- Iain MacDougall
- Ian Fraser
- Idalia Acosta
- Ildiko Halmagyi
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- Ingrid Buganova
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- Jardine M. J.
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- Lin Sun
- Lincoln Chapin
- Linong Ji
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- Liudmila Kvitkova
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- Luiza Despina Demian
- László Rosivall
- Ma Dovie Lallaine Ygpuara
- Mahaffey K. W.
- Manel Terns Riera
- Manish Saxena
- Manthi Hettiarachchi
- Manuel Muñoz Lopez Mendoza
- Manuel Muñoz Torres
- Manuela Schmidt
- Marc Rendell
- Marcel Twahirwa
- Marcelo Medina Fariña
- Marcora Mandreoli
- Marcus Gomes
- Margarita Temelkova
- Margarita Vejar
- Margit Mileder
- Margo Hudson
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- María Alicia Fernández Montenegro
- María Angustias Quesada Simón
- Masahiko Takai
- Masahiro Koizumi
- Masakiyo Wakasugi
- Masayo Yamada
- Mastura Ismail
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- Matthew Beacom
- Meg J Jardine
- Meg Jardine
- Meininger G.
- Melchor Alpizar Salazar
- Melemadathil Sreelatha
- Merce Perez Vera
- Mercedes Velo Plaza
- Michael Oliver
- Michael Robinson
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- Michael Thompson
- Michael Williams
- Michal Nowicki
- Michał Nowicki
- Michelle Zaniewski-Singh
- Mick Kumwenda
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- Migues Angel Reyes Rosano
- Mihaela Biscoveanu
- Mihaela-Magdalena Busegeanu
- Mihaly Dudas
- Milan Gupta
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- Minara Shamkhalova
- Minghui Zhao
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- Mircea Munteanu
- Mitsuru Tsujimoto
- Mohamed El-Shahawy
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- Mohanram Narayanan
- Mohd Daud Che Yusof
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- Neal B.
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- Neil Kumar
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- Nicole Li
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- Nina Patel
- Nizar Daboul
- Noble Gracious
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- Norsiah Ali
- Oleg Legun
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- Patrick English
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- Pavel Weiner
- Peak Mann Mah
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- Peggy Barnhill
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- Pere Alvarez Garcia
- Perkovic V.
- Peter Danos
- Peter Fulop
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- Philip Nicol
- Philippe Zaoui
- Phyllis August
- Piermarco Piatti
- Pierre Gourdy
- Pierre-Jean Saulnier
- Pietro Castellino
- Pilar Trueba
- Ping Tu
- Pollock C.
- Prasanth Surampudi
- Pusadee Suchinda
- Qinkai Chen
- Rachel Bregman
- Radica Alicic
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- Rajendran Alappan
- Rajiv Agarwal
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- Raju Sree Bhushan
- Rakesh Gulati
- Rakhi Khanna
- Rallabhandi Sankaram
- Raman Purighalla
- Ramesh Chandra Vyasam
- Ramesh Thimmaiah
- Ramon Berenguer
- Ramon Moreda
- Rangel Rangelov
- Rao K Satyanarayana
- Ravendran Govender
- Ravi Sarin
- Reddy Sreedhar
- Reginald Parker
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- Svetlana Goykhman
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- Sérgio Yamada
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- Takamoto Kodera
- Takashi Wada
- Takayuki Watanabe
- Tamara Malek Marin
- Tamas Oroszlan
- Tara Chang
- Tareq Nassar
- Tarissa Beatrice Zanata Petry
- Tatiana Koroleva
- Tatiana Morugova
- Tatiana Raskina
- Tatyana Zykova
- Te-Lin Hsia
- Terue Sakakibara
- Tetiana Zlova
- Tetsuji Niiya
- Tetyana Pertseva
- Tiago Schuch
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- Tom Christensen
- Tom Greene
- Tomas Drasnar
- Tomas Smith Casabella
- Tonatiu Diaz Escalante
- Toshihiko Yanase
- Toshio Kawada
- Vadym Vizir
- Vanassa Ratnasingam
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- Veselka Genadieva
- Vesna Popovic-Radinovic
- Viacheslav Marasaev
- Victor Commendatore
- Victor Saavedra Gajardo
- Vijayaraman Arutchelvam
- Viktor Margaritov
- Viktor Zaviriukha
- Viktoria Andreeva
- Vimladhevi Govender
- Vincent Pichette
- Vincent Woo
- Vira Tseluyko
- Virginia Esther Visco
- Vivek Sood
- Vivekan Jha
- Vladimir Dobronravov
- Vladimir Khirmanov
- Vladimir Tesar
- Vlado Perkovic
- Volker Burst
- Volodymyr Botsyurko
- Walter Guillermo Douthat
- Walter Pharr
- Wasim Hanif
- Wataru Yumita
- Wayne H-H Sheu
- Wayne Turner
- Wei Yen Kong
- Weihong Song
- Weiping Lu
- Wendy Lane
- Wenge Li
- Wheeler D. C.
- Wladmir Saporito
- Xuemei Li
- Xueqing Yu
- Yamil Canaan
- Yan Ren
- Yannick Le Meur
- Yaozhong Kong
- Yasuro Kumeda
- Yasushi Wakida
- Yavin Y.
- Yeong Hoon Kim
- Yevgeniya Svyshchenko
- Young Min Cho
- Yulia Samoylova
- Yung-Chuan Lu
- Yuriy Mostovoy
- Yuriy Shwartz
- Yvette Ethel Yap
- Zaynab Abejuela
- Zdravko Kamenov
- Zeid Khitan
- Zhang H.
- Zinman B.
- Zishan Ali
- Zuzana Ochodnicka
- Ângela Regina Nazario Sabbag
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star
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- Abac Adrian
- Abbott R.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aghaei Abchouyeh Maryam
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akcay Sarp
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi Simone
- Alex iandolo Guido
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
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- Won Seo Jin
- Wong Henry T.
- Wright J. L.
- Wright Mick
- Wu Chien-Ming
- Wu David S.
- Wu Hsun-Chung
- Wuchner E.
- Wysocki Daniel
- Xu Victoria
- Xu Yumeng
- Yaala M. Ben
- Yadav Nikesh
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
- Yamamoto Takahiro
- Yamamoto Takahiro S.
- Yamamura S.
- Yamazaki Ryo
- Yan S.
- Yan T.
- Yang F.
- Yang Fengwei
- Yang Kate Z.
- Yang Yi
- Yarbrough Zach
- Yasui H.
- Yeh S. -W.
- Yelikar A. B.
- Yin X.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuan S.
- Yuzurihara Hirotaka
- Zadrożny A.
- Zanolin M.
- Zeeshan M.
- Zelenova T.
- Zendri J. -P.
- Zeoli M.
- Zerrad M.
- Zevin Michael
- Zhang A. C.
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Ya
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 都丸 隆行
- Publication venue
- Publication date
- 23/04/2024
- Field of study
Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adamcewicz C.
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Almualla M.
- Altin Paul
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Anand S.
- Ananyeva A.
- Andersen R.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Aoumi M.
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Arif Shaikh Md
- Aritomi Naoki
- Armato F.
- Arnaud Nicolas
- Arogeti Megan
- Aronson Scott
- Arun K. G.
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- Babak Stanislav
- Badalyan A.
- Badaracco Francesca
- Badger C.
- Bae Sangwook
- Bagnasco Stefano
- Bai Y.
- Baier Jeremy
- Bajpai Rishabh
- Baka T.
- Ball M.
- Ballardin G.
- Ballmer S. W.
- Baltus Grégory
- Banagiri Sharan
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- Degallaix Jerome
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- Dell'Aquila Daniele
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- di giovanni Fabrizio
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- error error
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- Estevez Dimitri
- Etzel T.
- Evans C. R.
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- Fabrizi Federica
- Faedi F.
- Fafone Viviana
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- Fenyvesi Edit
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- Fidecaro Francesco
- Fiori Alessio
- Fiori Irene
- Fishbach Maya
- Fisher R. P.
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- Fiumara V.
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- Fleischer Svenja
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- Fornal Bartosz
- Forsyth P. W. F.
- Franceschetti K.
- Francisco Nuño Siles José
- Franke A.
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- Fukunaga I.
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- Gaetano Fronzé Gabriele
- Gair Jonathan
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- Galaudage S.
- Gallardo S.
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- García Quirós Cecilio
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- Gasbarra Claudio
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- Yu Hang
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- Zahoor Jan Aasim
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- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Álvarez-López S.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/08/2023
- Field of study
Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level
Ultralight vector dark matter search using data from the KAGRA O3GK run
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adamcewicz Christian
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antoni Ramis Vidal Felip
- Antonietta Palaia Maria
- Antonio Font Roda Jose
- Aoumi M.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Argianas L. Granda
- Arif Shaikh Md
- Aritomi Naoki
- Armato F.
- Arnaud Nicolas
- Arogeti Megan
- Aronson Scott
- Arun K. G.
- Ashton Gregory
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- MORALES ESTER. RUIZ.
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- More Anupreeta
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- Moreno Claudia
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- Yaala M. Ben
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- Yin X.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuzurihara Hirotaka
- Zadrożny A.
- Zahoor Jan Aasim
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- Zanolin M.
- Zeeshan M.
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- Zeoli M.
- Zerrad M.
- Zevin Michael
- Zhang A. C.
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Ya
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhong S.
- Zhou R.
- Zhu Zong-Hong
- Zucker M. E.
- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM
Two cases of HIVAN in young AIDS patients
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Biofuels from Pyrolysis of Third-Generation Biomass from Household and Garden Waste Composting Bin: Kinetics Analysis
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 01/06/2023
- Field of study
The modern society produces large amounts of household waste with high organic matter content. The vermicomposting of household waste produces high-value humic substances and is a way to stabilize organic material for later use as raw material (3rd generation biomass) for bioenergy proposes. A 6-month matured compost, combining vegetable and fruit scraps from domestic trash and grass and shrub clippings from yard waste, was evaluated to assess its potential as a raw material in pyrolysis processes. The pyrolysis activation energy (Kissinger) of the composted material showed values in the range of 200–300 kJ/mol, thus confirming its suitability for pyrolysis processes with promising H2 yields. The treatment of the composted material with H2SO4 and NaOH solution (boiling; 1 mol/L) led to the production of solid residues that present higher pyrolysis activation energies, reaching 550 kJ/mol for the most resilient fraction, which makes them suitable to produce carbonaceous materials (biochar) that will have incorporated the inorganics existing in the original compost (ashes 37.6%). The high content of inorganics would play a chief role during pyrolysis since they act as gasification promoters
Renal Impairment Impact and Survival Analysis in a Romanian Cohort of HIV-1(F1)-Infected Children and Adolescents
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 01/03/2023
- Field of study
Human immunodeficiency virus (HIV) is a lentivirus that is transmissible through blood and other body fluids. During the late 1980s and early 1990s, an estimated 10,000 Romanian children were infected with HIV-1 subtype F nosocomially through contaminated needles and untested blood transfusions. Romania was a special case in the global acquired immunodeficiency syndrome (AIDS) pandemic, displaying the largest population of HIV-infected children by parental transmission between 1987–1990. In total, 205 HIV-infected patients from the western part of Romania were analyzed in this retrospective study. Over 70% of them had experienced horizontal transmission from an unknown source, while vertical transmission was identified in only five cases. Most patients had a moderate to severe clinical manifestation of HIV infection, 77.56% had undergone antiretroviral (ARV) treatment, most of them (71.21%) had experienced no adverse reactions and many of those with HIV (90.73%) had an undetectable viral load. Renal impairment was detected in one third of patients (34.63%). Patients born before 1990, male patients, patients diagnosed with HIV before the age of 10, and those undernourished or with renal impairment had a shorter average survival time than the group born after 1990, female patients, patients receiving ARV treatment, patients with a normal body mass index (BMI) and those without renal impairment. Periodical monitoring of the estimated glomerular filtration rate (eGFR) level, as well as the detection of protein excretion, should be taken into consideration worldwide when monitoring HIV-positive patients; this in order to detect even asymptomatic chronic kidney disease (CKD), and to manage these patients and prolong their lives
Whose Job Will be Taken Over by a Computer? The Role of Personality in Predicting Job Computerizability over the Lifespan
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
New national and regional bryophyte records, 46
- Author
- Aleffi M.
- Asthana A.K.
- Aziz M. N.
- Cano Maria J.
- Costa D. Pinheiro da
- Dias E. M.
- Ellis Leonard T.
- Fedosov V.E.
- Fialová L.
- Germano S. R.
- Golovina E. O.
- Gremmen Niek J.M.
- Ignatova E.A.
- Ion Rodica Mariana
- Jimenez M.S.
- Kiebacher T.
- Konrat Matt von
- Kozhin M. N.
- Larrain J.
- Lebouvier Marc
- Long David G.
- Maity Debabrata
- Ochyra Ryszard
- Omar I.
- Parnikoza Ivan
- Plášek Vitezslav
- Poponessi Silvia
- Rawat Krishna Kumar
- Sabovljevic Aneta D.
- Sabovljevic Marko S.
- Saha P.
- Sahu Vinay
- Santos Nivea Dias dos
- Sawicki Jakub
- Silva Juliana B.
- Skoupá Z.
- Srivastava Pankaj
- Stefănuţ S.
- Suarez Guillermo M.
- Suleiman M.
- Sun Byhung-Yun
- Vana Jiri
- Wojcik T.
- Yoon Y.J.
- Zarnowiec J.
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2016
- Field of study
International audienceno abstrac