Understanding Personal Data in the World of Social Media

Personal data is behind many of the online interactions that people have through social media and other online sites and services. This data allows sites to understand their users, which in turn allows them to provide better content for their users. This data is also used to determine user interests, which these online services use to target more relevant advertising to their users, and share the information that they collect about their users with third parties. It is only recently that this personal data is being regulated by lawmakers, the businesses running these sites are held accountable for managing the data that they collect on users, and that the users of these sites are given a greater degree of control over how their data is used, however these regulations are not universal. Additionally, the data that online services have collected on their users has been used by third parties for malicious purposes, such as the Russian interference in the 2016 U.S. presidential election. The collection of personal data allows for the development of new technologies such as facial recognition and genealogy through DNA, but without regulation, moral dilemmas surround the collection and use of such personal data. For my capstone I built a website structured like a social media application. On this site I have written a number of posts that communicate the findings of my research to the users of this site. Additionally, on this website visitors are able to see some of the type of personal data that social media sites can collect about them while they use the service

Costs of colour change in fish: food intake and behavioural decisions

Many animals, particularly reptiles, amphibians, fish and cephalopods, have the ability to change their body colour, for functions including thermoregulation, signalling and predator avoidance. Many fish plastically darken their body colouration in response to dark visual backgrounds, and this functions to reduce predation risk. Here, we tested the hypotheses that colour change in fish (1) carries with it an energetic cost and (2) affects subsequent shoal and habitat choice decisions. We demonstrate that guppies (Poecilia reticulata) change colour in response to dark and light visual backgrounds, and that doing so carries an energetic cost in terms of food consumption. By increasing food intake, however, guppies are able to maintain growth rates and meet the energetic costs of changing colour. Following colour change, fish preferentially choose habitats and shoals that match their own body colouration, and maximise crypsis, thus avoiding the need for further colour change but also potentially paying an opportunity cost associated with restriction to particular habitats and social associates. Thus, colour change to match the background is complemented by behavioural strategies, which should act to maximise fitness in variable environments. © 2013. Published by The Company of Biologists Ltd

Complex retreat behavior in experimental barrier island response to base level rise

University of Minnesota M.S. thesis. August 2019. Major: Earth Sciences. Advisor: Chris Paola. 1 computer file (PDF); viii, 57 pages.Barrier islands act as natural barriers between the ocean and the mainland. These islands create protected, low energy environments behind them that are important ecological and economic hubs. Barrier islands are naturally low-laying features and are susceptible to drowning from sea level rise. However, previous work suggests that barrier islands can retreat upslope to keep up with sea level rise and maintain their subaerial extent. To explore this idea, we performed physical experiments where barrier islands were subjected to a constant relative sea level rise (RSL) and constant wave environment. We tracked the islands through time with overhead images and periodic laser elevation scans. Time series of island location show that the islands did not retreat at constant rates through the transgression. Rather, overall long-term retreat occurred through a “stick-slip” motion comprising stationary intervals alternating with backward steps. The source of this complex behavior is a cycling between two morphologies: one where an island has a developed ridge and another where no ridge is present. Sea level rise allows waves to overtop the island and erode the ridge that once kept the waves at bay. That sediment is deposited behind the island, moving the barrier landward. Waves continue to push sediment back towards the mainland until the island becomes too wide for waves to carry sediment all the way across the island. This begins a process of backfilling the overwash fan, eventually creating a new ridge. These simple experiments support previous theoretical suggestions that periodic overwash is a key part of a barrier island’s behavior during a transgression, and that this can lead to punctuated retreat even when RSL rise is steady

Leg ulceration as a long-term complication of deep vein thrombosis

AbstractObjectiveTo evaluate the role of deep vein thrombosis as a cause of leg ulcers.Patients and methodsA population-based, case-control study was conducted in Central and North Auckland, New Zealand. Cases comprised 241 people aged 40 to 99 years and on the electoral roll, with current leg ulcers (all types). Cases were identified by means of notification from health professionals and by self-referral. Controls were 224 people in the same age group, without leg ulcers, who were selected from the electoral roll by using a stratified random sampling process.Main outcome measuresThe occurrence of leg ulceration as a consequence of exposure to deep vein thrombosis or being at high risk of deep vein thrombosis (that is, people with a family history of deep vein thrombosis, and/or a history of leg fracture and/or hip, leg, or foot surgery).ResultsAfter adjustment for age, sex, and other potential confounding factors, people who had a diagnosed thromboembolism were at almost three times higher risk of having a leg ulcer (odds ratio, 2.92; 95% confidence interval (CI), 1.47 to 6.08). In addition, people who had been at high risk of a venous thrombosis but were not diagnosed with this condition (eg, people with a history of major leg surgery) were also at increased risk of ulceration (odds ratio, 2.25; 95% CI, 1.49-3.42). Overall, 56% (95% CI, 33% - 71%) of leg ulcers were attributed to being at high risk of deep vein thrombosis.ConclusionsDeep vein thrombosis and factors that place people at high risk of deep vein thrombosis are an important cause of leg ulcers in older people. This finding strengthens the rationale for the routine and long-term use of thromboprophylaxis, particularly in high-risk patients

The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells

Background Oocytes mature in ovarian follicles surrounded by granulosa cells. During follicle growth, granulosa cells replicate and secrete hormones, particularly steroids close to ovulation. However, most follicles cease growing and undergo atresia or regression instead of ovulating. To investigate the effects of stimulatory (follicle-stimulating hormone; FSH) and inhibitory (tumour necrosis factor alpha; TNFα) factors on the granulosa cell transcriptome, bovine ovaries were obtained from a local abattoir and pools of granulosa cells were cultured in vitro for six days under defined serum-free conditions with treatments present on days 3–6. Initially dose–response experiments (n = 4) were performed to determine the optimal concentrations of FSH (0.33 ng/ml) and TNFα (10 ng/ml) to be used for the microarray experiments. For array experiments cells were cultured under control conditions, with FSH, with TNFα, or with FSH plus TNFα (n = 4 per group) and RNA was harvested for microarray analyses. Results Statistical analysis showed primary clustering of the arrays into two groups, control/FSH and TNFα/TNFα plus FSH. The effect of TNFα on gene expression dominated that of FSH, with substantially more genes differentially regulated, and the pathways and genes regulated by TNFα being similar to those of FSH plus TNFα treatment. TNFα treatment reduced the endocrine activity of granulosa cells with reductions in expression of FST, INHA, INBA and AMH. The top-ranked canonical pathways and GO biological terms for the TNFα treatments included antigen presentation, inflammatory response and other pathways indicative of innate immune function and fibrosis. The two most significant networks also reflect this, containing molecules which are present in the canonical pathways of hepatic fibrosis/hepatic stellate cell activation and transforming growth factor β signalling, and these were up regulated. Upstream regulator analyses also predicted TNF, interferons γ and β1 and interleukin 1β. Conclusions In vitro, the transcriptome of granulosa cells responded minimally to FSH compared with the response to TNFα. The response to TNFα indicated an active process akin to tissue remodelling as would occur upon atresia. Additionally there was reduction in endocrine function and induction of an inflammatory response to TNFα that displays features similar to immune cells

Student Awareness of Models in First-Year Engineering Courses

Contribution: This study assesses more than 800 students\u27 awareness of engineering model types before and after taking two first-year engineering courses across two semesters and evaluates the effect of each course. Background: All engineers must be able to apply and create models to be effective problem solvers, critical thinkers, and innovative designers. To help them develop these skills, as a first step, it is essential to assess how to increase students\u27 awareness of engineering models. According to Bloom\u27s taxonomy, the lower remember and understand levels, which encompass awareness, are necessary for achieving the higher levels, such as apply, analyze, evaluate, and create. Research Questions: To what extent did student awareness of model types change after taking introductory engineering courses? To what extent did student awareness of model types differ by course or semester? Methodology: In this study, a survey was designed and administered at the beginning and end of the semester in two first-year engineering courses during two semesters in a mid-sized private school. The survey asked students questions about their definition of engineering modeling and different types of models. Findings: Overall, student awareness of model types increased from the beginning of the semester toward the end of the semester, across both semesters and courses. There were some differences between course sections, however, the students\u27 awareness of the models at the end of the academic year was similar for both groups

Could perturbed fetal development of the ovary contribute to the development of polycystic ovary syndrome in later life?

Polycystic ovary syndrome (PCOS) affects around 10% of young women, with adverse consequences on fertility and cardiometabolic outcomes. PCOS appears to result from a genetic predisposition interacting with developmental events during fetal or perinatal life. We hypothesised that PCOS candidate genes might be expressed in the fetal ovary when the stroma develops; mechanistically linking the genetics, fetal origins and adult ovarian phenotype of PCOS. In bovine fetal ovaries (n = 37) of 18 PCOS candidate genes only SUMO1P1 was not expressed. Three patterns of expression were observed: early gestation (FBN3, GATA4, HMGA2, TOX3, DENND1A, LHCGR and FSHB), late gestation (INSR, FSHR, and LHCGR) and throughout gestation (THADA, ERBB4, RAD50, C8H9orf3, YAP1, RAB5B, SUOX and KRR1). A splice variant of FSHB exon 3 was also detected early in the bovine ovaries, but exon 2 was not detected. Three other genes, likely to be related to the PCOS aetiology (AMH, AR and TGFB1I1), were also expressed late in gestation. Significantly within each of the three gene groups, the mRNA levels of many genes were highly correlated with each other, despite, in some instances, being expressed in different cell types. TGFβ is a well-known stimulator of stromal cell replication and collagen synthesis and TGFβ treatment of cultured fetal ovarian stromal cells inhibited the expression of INSR, AR, C8H9orf3 and RAD50 and stimulated the expression of TGFB1I1. In human ovaries (n = 15, < 150 days gestation) many of the same genes as in bovine (FBN3, GATA4, HMGA2, FSHR, DENND1A and LHCGR but not TOX3 or FSHB) were expressed and correlated with each other. With so many relationships between PCOS candidate genes during development of the fetal ovary, including TGFβ and androgen signalling, we suggest that future studies should determine if perturbations of these genes in the fetal ovary can lead to PCOS in later life

Georgia Aquarium Design Space Analysis and Optimization

AbstractThe Ocean Voyager exhibit residing at the Georgia Aquarium Inc. (GAI) is one of the largest reef gallon aquariums in the world, with a capacity greater than 6.2M gallons. Reef aquariums are closed systems and must compensate by ‘turning over’ their complete volume of water many times a day through biological, chemical, and mechanical filtration. Due to the Georgia Aquarium being a non-profit organization, GAI sought to investigate ways to maximize efficiency and lower operating costs. This paper will focus on using low-cost software solutions to perform trade space analyses and optimization directed towards the Ocean Voyager exhibit and related GA Aquarium life support and energy systems.The software solution herein demonstrates a top-down System of Systems (SoS) to subsystem modeling approach that provides decision makers with interdisciplinary dashboard-level tools to visualize system design. The goal of the analysis is to provide executive level decision-making support for designing or enhancing existing complex systems and SoS. The analysis was performed as a capstone project by Georgia Tech graduate students progressing from cradle to finish in just 9 weeks to show the benefits of systems engineering to Georgia Aquarium staff. Integrating software SE tools into a single, aggregate model enables project engineers and decision makers to direct design directions with confidence

Building Information Modelling (Bim) within the Australian construction related small and medium sized enterprises: awareness, practices and drivers

Review of literature on BIM reveals a bias towards focusing on large companies and overlooking SMEs in Australia. To bridge this gap of knowledge, this study explores the level of awareness, practices and drivers of BIM among SMEs within the Australian construction industry through the lenses of theories of innovation diffusion in construction companies. In so doing, a questionnaire survey was administered and 41 responses received from these SMEs engaged in commercial, industrial and public works. Accordingly, seven face-to-face interviews were conducted to compensate for the small sample size and to expand the survey data in more depth. The findings brought to light that current knowledge of BIM in SMEs is one-sided and negatively biased with a tendency towards highlighting challenges and overlooking the advantages. Besides, a significant association was spotted between the awareness of values of BIM and the practices related with BIM in SMEs. Additionally, the most influential drivers for BIM were turned out to be all associated with economic gains for the business of the companies alongside clients\u27 demands. Furthermore, it was revealed that practices associated with BIM and awareness of BIM are similar across different sizes of SMEs