20 research outputs found
Estimativas mensais da formação bruta de capital fixo pública no Brasil (2002-2010)
This article presents new monthly estimates of the gross fixed capital formation of the Brazilian general government for the 2002-2010 years. A significant research effort was made to carry out the estimations. First, the many differences between the concepts of "public investment" (as used in the Brazilian public accounting manuals) and "gross fixed capital formation of the general government" (as used in the United Nations System of National Accounts) were carefully identified, and so were the peculiarities of the Brazilian budget process that distort official estimates of the annual gross fixed capital formation of the Brazilian general government and affect the precision of naive estimates of the same variable in higher frequencies. Second, several procedures were developed to correct or mitigate these problems. Finally, additional information was obtained from 20 out of 26 Brazilian states, the federal district, and tens of (large) municipalities in order to allow us to circumvent the relative scarcity of information on the finances of Brazilian state and local governments.Este artigo apresenta estimativas inéditas de séries mensais da formação bruta de capital fixo (FBCF) das administrações públicas no Brasil de 2002 a 2010. A estimação exigiu um esforço significativo de pesquisa. Em primeiro lugar, realizou-se uma análise criteriosa dos conceitos da contabilidade pública e da contabilidade nacional, enfatizando-se as peculiaridades do processo orçamentário brasileiro que enviesam as estimativas anuais dos investimentos públicos divulgadas nas estatísticas oficiais e que afetam a precisão das informações de alta frequência. Em segundo lugar, desenvolveram-se procedimentos para mitigar estes problemas. Por fim, buscou-se contornar a escassez de informações dos governos subnacionais solicitando-se informações adicionais de centenas de contadores públicos, técnicos ou secretários de Fazenda/Planejamento de todos os estados da Federação, do Distrito Federal (DF) e dos maiores municípios
Estimativas mensais da formação bruta de capital fixo pública no Brasil (2002-2010)
Este artigo apresenta estimativas inéditas de séries mensais da formação bruta de capital fixo (FBCF) das administrações públicas no Brasil de 2002 a 2010. A estimação exigiu um esforço significativo de pesquisa. Em primeiro lugar, realizou-se uma análise criteriosa dos conceitos da contabilidade pública e da contabilidade nacional, enfatizando-se as peculiaridades do processo orçamentário brasileiro que enviesam as estimativas anuais dos investimentos públicos divulgadas nas estatísticas oficiais e que afetam a precisão das informações de alta frequência. Em segundo lugar, desenvolveram-se procedimentos para mitigar estes problemas. Por fim, buscou-se contornar a escassez de informações dos governos subnacionais solicitando-se informações adicionais de centenas de contadores públicos, técnicos ou secretários de Fazenda/Planejamento de todos os estados da Federação, do Distrito Federal (DF) e dos maiores municípios.This article presents new monthly estimates of the gross fixed capital formation of the Brazilian general government for the 2002-2010 years. A significant research effort was made to carry out the estimations. First, the many differences between the concepts of "public investment" (as used in the Brazilian public accounting manuals) and "gross fixed capital formation of the general government" (as used in the United Nations System of National Accounts) were carefully identified, and so were the peculiarities of the Brazilian budget process that distort official estimates of the annual gross fixed capital formation of the Brazilian general government and affect the precision of naive estimates of the same variable in higher frequencies. Second, several procedures were developed to correct or mitigate these problems. Finally, additional information was obtained from 20 out of 26 Brazilian states, the federal district, and tens of (large) municipalities in order to allow us to circumvent the relative scarcity of information on the finances of Brazilian state and local governments
Analyses of the probiotic property and stress resistance-related genes of Lactococcus lactis subsp. lactis NCDO 2118 through comparative genomics and in vitro assays.
Lactococcus lactis subsp. lactis NCDO 2118 was recently reported to alleviate colitis symptoms via its anti-inflammatory and immunomodulatory activities, which are exerted by exported proteins that are not produced by L. lactis subsp. lactis IL1403. Here, we used in vitro and in silico approaches to characterize the genomic structure, the safety aspects, and the immunomodulatory activity of this strain. Through comparative genomics, we identified genomic islands, phage regions, bile salt and acid stress resistance genes, bacteriocins, adhesion-related and antibiotic resistance genes, and genes encoding proteins that are putatively secreted, expressed in vitro and absent from IL1403. The high degree of similarity between all Lactococcus suggests that the Symbiotic Islands commonly shared by both NCDO 2118 and KF147 may be responsible for their close relationship and their adaptation to plants. The predicted bacteriocins may play an important role against the invasion of competing strains. The genes related to the acid and bile salt stresses may play important roles in gastrointestinal tract survival, whereas the adhesion proteins are important for persistence in the gut, culminating in the competitive exclusion of other bacteria. Finally, the five secreted and expressed proteins may be important targets for studies of new anti-inflammatory and immunomodulatory proteins. Altogether, the analyses performed here highlight the potential use of this strain as a target for the future development of probiotic foods