14 research outputs found

    Solvability for a nonlinear coupled system of Kirchhoff type for the beam equations with nonlocal boundary conditions

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    In this paper, we investigate a mathematical model for a nonlinear coupled system of Kirchhoff type of beam equations with nonlocal boundary conditions. We establish existence, regularity and uniqueness of strong solutions. Furthermore, we prove the uniform rate of exponential decay. The uniform rate of polynomial decay is considered

    Global solvability and asymptotic behavior for a nonlinear coupled system of viscoelastic waves with memory in a noncylindrical domain

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    AbstractIn this paper we prove the exponential decay in the case n>2, as time goes to infinity, of regular solutions for a nonlinear coupled system of wave equations with memory and weak dampingutt−Δu+∫0tg1(t−s)Δu(s)ds+αut+h(u−v)=0inQˆ,vtt−Δv+∫0tg2(t−s)Δv(s)ds+αvt−h(u−v)=0inQˆ, in a noncylindrical domains Qˆ of Rn+1 (n⩾1) under suitable hypotheses on the scalar functions h, g1 and g2, and where α is a positive constant. We show that such dissipation is strong enough to produce uniform rate decay. Besides, the coupled is nonlinear which brings up some additional difficulties, which make the problem interesting. We establish existence and uniqueness of regular solutions for any n⩾1

    Sulfated fucan as support for antibiotic immobilization

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    Xylofucoglucuronan from Spatoglossum schröederi algae was tested as a support for antibiotic immobilization. The polysaccharide (20 mg in 6 ml) was first activated using carbodiimide, 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide methiodide (20 mg in 2 ml), under stirring for 1 h at 25ºC and pH from 4.5 to 5.0. After adjusting the pH to 8.0, either gentamicin or amikacin (62.5 mg in 1.25 ml) was then immobilized on this chemically modified polysaccharide with shaking for 24 h in a cold room. Infrared spectra of the activated carbodiimide xylofucoglucuronan showed two bands to carbonyl (C = O at 1647.9 and 1700.7 cm-1) and to amide (C<FONT FACE=Symbol>Ý</FONT>-NH2) groups (1662.8 and 1714.0 cm-1). Microbial characterization of the derivatives was carried out by the disk diffusion method using Staphylococcus aureus or Klebsiella pneumoniae incorporated in Müller Hinton medium. Inhibition halos of bacterial growth were observed for the antibiotics immobilized on this sulfated heteropolysaccharide before and after dialysis. However, the halos resulting from the samples after dialysis were much smaller, suggesting that dialysis removed either non-covalently bound antibiotic or other small molecules. In contrast, bacterial growth was not inhibited by either xylofucoglucuronan or its activated form or by gentamicin or amikacin after dialysis. An additional experiment was carried out which demonstrated that the sulfated heteropolysaccharide was hydrolyzed by the microorganism. Therefore, the antibiotic immobilized on xylofucoglucuronan can be proposed as a controlled drug delivery system. Furthermore, this sulfated heteropolysaccharide can be extracted easily from sea algae Spatoglossum schröederi

    Complete genome sequences of corynebacterium pseudotuberculosis strains 3/99-5 and 42/02-A, isolated from sheep in Scotland and Australia, respectively

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    Here, we report the whole-genome sequences of two ovine-pathogenic Corynebacterium pseudotuberculosis isolates: strain 3/99-5, which represents the first C. pseudotuberculosis genome originating from the United Kingdom, and 42/02-A, the second from Australia. These genome sequences will contribute to the objective of determining the global pan-genome of this bacterium
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