Life satisfaction trajectories during adolescence and the transition to young adulthood: Findings from a longitudinal study of Mexican-origin youth.

Despite the importance of life satisfaction for health and well-being, there is a paucity of longitudinal studies tracking changes in life satisfaction in ethnic minority youth. In a sample of 674 Mexican-origin youth, the present research examined life satisfaction trajectories from middle (age 14) to late adolescence (age 17) and from late adolescence to young adulthood (age 21). On average, life satisfaction did not change significantly from age 14 to 17, and then decreased from age 17 to 21 (d = .30), perhaps reflecting difficulties transitioning into adult roles. Drawing on ecological systems theory, we examined both proximal (i.e., family) and distal (i.e., social-contextual) environmental factors (measured via self- and parent-reports) that may account for between-person variation in life satisfaction trajectories. Youth with more positive family environments in middle adolescence (age 14) had higher mean life satisfaction from middle adolescence to young adulthood (age 21). In contrast, youth with more negative family environments and who experienced greater economic hardship and more ethnic discrimination in middle adolescence (age 14) had lower life satisfaction during this period. Many of these factors also predicted change in life satisfaction from middle (age 14) to late adolescence (age 17), but not from late adolescence to young adulthood (age 21). This research extends the current understanding of life satisfaction during a critical developmental period in an understudied population. (PsycInfo Database Record (c) 2021 APA, all rights reserved)

Toadfish

24 p. : ill. ; 24 cm.Includes bibliographical references (p. 21-24)."Opsanus phobetron is described from the western Bahamas, Cuba, and the Isle of Pines. It was observed to nest in late December at Bimini, Bahamas. The black mouth functions as a warning mechanism, and under low albedo conditions, as at Bimini, the dark coloration is indicated to be of social significance. Attention is called to unidentified samples of Opsanus from Little Bahama Bank and the Gulf of Campeche. The ranges and recognition characters of O. pardus, O. tau, O. beta, and O. barbatus are discussed. Opsanus vandeuseni Fowler is referred to the synonymy of Opsanus beta (Goode and Bean). Opsanus hildebrandi Breder is placed in Marcgravia Jordan and appears not to be identical with M. ctyptocentra (Cuvier and Valenciennes). The low numbers of dorsal and anal rays attributed to Opsanus in the literature are valid if the Queensland genus Batrachoemus Ogilby is considered identical with Opsanus. Published paleotemperature measurements indicate that the 'tropical' Atlantic and Caribbean regions were not tropical during the last glacial period. The trans-Florida faunal province, now absent from southern Florida, was continuous around the southern tip of the Florida land mass; at the same time coral reefs were absent from most of the West Indies, and the shore fauna was predominantly temperate in the north and predominantly subtropical in the south. It is improbable that the Florida peninsula neck was submerged during Pleistocene interglacial periods. The presence of marine fishes in Florida fresh waters is not considered significant from the standpoint of historical zoogeography, and it is suggested that the elevated chlorinities in Florida fresh waters are maintained by current processes. Even if the neck of the Florida peninsula had been drowned, the Gulf of Mexico populations of trans-Florida fishes probably could not utilize the passage, as the temperatures would have been too high. The Gulf of Mexico disjunct trans-Florida populations are interpreted as glacial rather than interglacial relicts, and a comparison is drawn between the Gulf of Mexico and the Sea of Okhotsk. Because the spawning threshold temperature of Opsanus parallels the minimal thermal tolerance of reef corals, Opsanus is considered to be an 'indicator' of temperate coastal waters. Owing to thermal requirements and tolerances, Opsanus survives as a glacial relict in a few West Indian localities. During the last glacial period, the northern distributional limit for Opsanus may have been as far south as southern Florida. Opsanus, lacking pelagic life-history stages, could have dispersed through the West Indies by passive transport during storms"--P. 20-21

Harnessing Museum Resources for the Census of Marine Life: The FISHNET Project

No abstract is available for this item

Effect size guidelines for cross-lagged effects

Cross-lagged models are by far the most commonly used method to test the prospective effect of one construct on another, yet there are no guidelines for interpreting the size of cross-lagged effects. This research aims to establish empirical benchmarks for cross-lagged effects, focusing on the cross-lagged panel model (CLPM) and the random intercept cross-lagged panel model (RI-CLPM). We drew a quasirepresentative sample of studies published in four subfields of psychology (i.e., developmental, social–personality, clinical, and industrial–organizational). The dataset included 1,028 effect sizes for the CLPM and 302 effect sizes for the RI-CLPM, based on data from 174 samples. For the CLPM, the 25th, 50th, and 75th percentiles of the distribution corresponded to cross-lagged effect sizes of .03, .07, and .12, respectively. For the RI-CLPM, the corresponding values were .02, .05, and .11. Effect sizes did not differ significantly between the CLPM and RI-CLPM. Moreover, effect sizes did not differ significantly across subfields and were not moderated by design characteristics. However, effect sizes were moderated by the concurrent correlation between the constructs and the stability of the predictor. Based on the findings, we propose to use .03 (small effect), .07 (medium effect), and .12 (large effect) as benchmark values when interpreting the size of cross-lagged effects, for both the CLPM and RI-CLPM. In addition to aiding in the interpretation of results, the present findings will help researchers plan studies by providing information needed to conduct power analyses and estimate minimally required sample sizes

Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS

The Type II Secretion System (T2SS) is a molecular machine that drives the secretion of fully-folded protein substrates across the bacterial outer membrane. A key element in the machinery is the secretin: an integral, multimeric outer membrane protein that forms the secretion pore. We show that three distinct forms of T2SSs can be distinguished based on the sequence characteristics of their secretin pores. Detailed comparative analysis of two of these, the Klebsiella-type and Vibrio-type, showed them to be further distinguished by the pilotin that mediates their transport and assembly into the outer membrane. We have determined the crystal structure of the novel pilotin AspS from Vibrio cholerae, demonstrating convergent evolution wherein AspS is functionally equivalent and yet structurally unrelated to the pilotins found in Klebsiella and other bacteria. AspS binds to a specific targeting sequence in the Vibrio-type secretins, enhances the kinetics of secretin assembly, and homologs of AspS are found in all species of Vibrio as well those few strains of Escherichia and Shigella that have acquired a Vibrio-type T2SS

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.

Expansion of the polyglutamine (polyQ) tract within the androgen receptor (AR) causes neuromuscular degeneration in individuals with spinobulbar muscular atrophy (SBMA). PolyQ AR has diminished transcriptional function and exhibits ligand-dependent proteotoxicity, features that have both been implicated in SBMA; however, the extent to which altered AR transcriptional function contributes to pathogenesis remains controversial. Here, we sought to dissociate effects of diminished AR function from polyQ-mediated proteotoxicity by enhancing the transcriptional activity of polyQ AR. To accomplish this, we bypassed the inhibitory effect of AR SUMOylation (where SUMO indicates small ubiquitin-like modifier) by mutating conserved lysines in the polyQ AR that are sites of SUMOylation. We determined that replacement of these residues by arginine enhances polyQ AR activity as a hormone-dependent transcriptional regulator. In a murine model, disruption of polyQ AR SUMOylation rescued exercise endurance and type I muscle fiber atrophy; it also prolonged survival. These changes occurred without overt alterations in polyQ AR expression or aggregation, revealing the favorable trophic support exerted by the ligand-activated receptor. Our findings demonstrate beneficial effects of enhancing the transcriptional function of the ligand-activated polyQ AR and indicate that the SUMOylation pathway may be a potential target for therapeutic intervention in SBMA

The need to promote behaviour change at the cultural level: one factor explaining the limited impact of the MEMA kwa Vijana adolescent sexual health intervention in rural Tanzania. A process evaluation

Background - Few of the many behavioral sexual health interventions in Africa have been rigorously evaluated. Where biological outcomes have been measured, improvements have rarely been found. One of the most rigorous trials was of the multi-component MEMA kwa Vijana adolescent sexual health programme, which showed improvements in knowledge and reported attitudes and behaviour, but none in biological outcomes. This paper attempts to explain these outcomes by reviewing the process evaluation findings, particularly in terms of contextual factors. Methods - A large-scale, primarily qualitative process evaluation based mainly on participant observation identified the principal contextual barriers and facilitators of behavioural change. Results - The contextual barriers involved four interrelated socio-structural factors: culture (i.e. shared practices and systems of belief), economic circumstances, social status, and gender. At an individual level they appeared to operate through the constructs of the theories underlying MEMA kwa Vijana - Social Cognitive Theory and the Theory of Reasoned Action – but the intervention was unable to substantially modify these individual-level constructs, apart from knowledge. Conclusion - The process evaluation suggests that one important reason for this failure is that the intervention did not operate sufficiently at a structural level, particularly in regard to culture. Recently most structural interventions have focused on gender or/and economics. Complementing these with a cultural approach could address the belief systems that justify and perpetuate gender and economic inequalities, as well as other barriers to behaviour change