Compact gml: merging mobile computing and mobile cartography

The use of portable devices is moving from "Wireless Applications", typically implemented as browsing-on-the-road, to "Mobile Computing", which aims to exploit increasing processing power of consumer devices. As users get connected with smartphones and PDAs, they look for geographic information and location-aware services. While browser-based approaches have been explored (using static images or graphics formats such as Mobile SVG), a data model tailored for local computation on mobile devices is still missing. This paper presents the Compact Geographic Markup Language (cGML) that enables design and development of specific purpose GIS applications for portable consumer devices where a cGML document can be used as a spatial query result as well

The cgml: a xml language for mobile cartography

Increasing processing power and storage capabilities encourage systematic adoption of high-end mobile devices, such as programmable cellular phones and wireless-enabled PDA to implement new exciting applications. The performances of modern mobile devices are bringing innovative scenarios, based on position awareness and ambient intelligence paradigms. The market is moving from old 'Wireless Applications' approach to Mobile Computing, which aims to exploit mobile host capabilities. This paper presents the compact Geographic Markup Language (cGML), an XML-based language defined to enable design and development of LBS applications specific for mobile devices, and an example of client-server architecture using it

Identification alone versus intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroid surgery: experience of 2034 consecutive patients

Background: The aim of this study was to evaluate the ability of intraoperative neuromonitoring in reducing the postoperative recurrent laryngeal nerve palsy rate by a comparison between patients submitted to thyroidectomy with intraoperative neuromonitoring and with routine identification alone. Methods: Between June 2007 and December 2012, 2034 consecutive patients underwent thyroidectomy by a single surgical team. We compared patients who have had neuromonitoring and patients who have undergone surgery with nerve visualization alone. Patients in which neuromonitoring was not utilized (Group A) were 993, patients in which was utilized (group B) were 1041. Results: In group A 28 recurrent laryngeal nerve injuries were observed (2.82%), 21 (2.11%) transient and 7 (0.7%) permanent. In group B 23 recurrent laryngeal nerve injuries were observed (2.21%), in 17 cases (1.63%) transient and in 6 (0.58%) permanent. Differences were not statistically significative. Conclusions: Visual nerve identification remains the gold standard of recurrent laryngeal nerve management in thyroid surgery. Neuromonitoring helps to identify the nerve, in particular in difficult cases, but it did not decrease nerve injuries compared with visualization alone. Future studies are warranted to evaluate the benefit of intraoperative neuromonitoring in thyroidectomy, especially in conditions in which the recurrent nerve is at high risk of injury. Keywords: Neuromonitoring, Recurrent laryngeal nerve, Thyroidectom

Il cgml: una soluzione basata su xml per la rappresentazione di mappe vettoriali su dispositivi mobili

L’evoluzione tecnologica dei dispositivi mobili, in termini di potenza di calcolo, capacità di visualizzazione e memorizzazione, e il proliferare di sistemi di connessione a banda larga su rete locale wireless (WiFi) e cellulare (UMTS), permette la gestione di dati complessi quali le mappe vettoriali e l’accesso ai Location Based Service (LBS) per mezzo di un telefono cellulare o un palmare. L’uso di linguaggi XML nel settore dei LBS condiziona la struttura delle funzionalità e dei dati ma garantisce l’interoperabilità dei servizi. Un esempio è il linguaggio GML (Geographic Markup Language) standard de facto nello scambio dei dati tra sistemi GIS e nella rappresentazione dell’informazione geografica. Il GML non è orientato alla rappresentazione di mappe vettoriali, è quindi necessario trasformarlo in un altro linguaggio XML, ad esempio il linguaggio grafico SVG (Scalable Vector Graphics). Per evitare la separazione tra il dato geografico (GML) e la sua visualizzazione (Mobile SVG) ma usando comunque le mappe vettoriali su dispositivi mobili, abbiamo definito il cGML (compact Geographic Markup Language). La rappresentazione di un dato tramite cGML è una mappa vettoriale e come tale può essere utilizzata nella presentazione grafica, ma allo stesso momento è anche un contenitore di insiemi di dati geo-riferiti, omogenei per semantica, utilizzabili in elaborazioni locali sul dispositivo mobile.Enhanced mobile device performances, in terms of CPU power, memory capacity, display capabilities and adoption of wideband connectivity based on local wireless (WiFi) and cellular (UMTS) networks, bring interactive mapping and access to Location Based Services (LBS) to mobile phones and PDAs. The use of XML language in the LBS influences data structure, functionalities and performances; although it could be time and memory expensive, it guarantees service interoperability. The GML language (Geographic Markup Language) is "de facto" standard in data exchanging between Geographic Information Systems. The GML has not been designed to represent vector map: it has to be transformed into another XML language, for example the graphical-oriented XML language Mobile SVG. To avoid the separation between the geographic data (GML) and its visualization (Mobile SVG), keeping vector mapping on mobile devices, we have designed the cGML (compact Geographic Markup Language). The data encoded using cGML is a vector map, so that it can be used in the graphic representation, but at the same time it is a container of geographical related data set, homogenous for semantic and usable in local processing on the mobile device

A metabolomic approach to animal vitreous humor topographical composition: A pilot study

The purpose of this study was to evaluate the feasibility of a 1H-NMR-based metabolomic approach to explore the metabolomic signature of different topographical areas of vitreous humor (VH) in an animal model. Five ocular globes were enucleated from five goats and immediately frozen at 280uC. Once frozen, three of them were sectioned, and four samples corresponding to four different VH areas were collected: the cortical, core, and basal, which was further divided into a superior and an inferior fraction. An additional two samples were collected that were representative of the whole vitreous body. 1H-NMR spectra were acquired for twenty-three goat vitreous samples with the aim of characterizing the metabolomic signature of this biofluid and identifying whether any site-specific patterns were present. Multivariate statistical analysis (MVA) of the spectral data were carried out, including Principal Component Analysis (PCA), Hierarchical Cluster Analysis (HCA), and Partial Least Squares Discriminant Analysis (PLS-DA). A unique metabolomic signature belonging to each area was observed. The cortical area was characterized by lactate, glutamine, choline, and its derivatives, N-acetyl groups, creatine, and glycerol; the core area was characterized by glucose, acetate, and scyllo-inositol; and the basal area was characterized by branched-chain amino acids (BCAA), betaine, alanine, ascorbate, lysine, and myo-inositol. We propose a speculative approach on the topographic role of these molecules that are mainly responsible for metabolic differences among the as-identified areas. 1H-NMR-based metabolomic analysis has shown to be an important tool for investigating the VH. In particular, this approach was able to assess in the samples here analyzed the presence of different functional areas on the basis of a different metabolite distribution.The purpose of this study was to evaluate the feasibility of a 1H-NMR-based metabolomic approach to explore the metabolomic signature of different topographical areas of vitreous humor (VH) in an animal model. Five ocular globes were enucleated from five goats and immediately frozen at -80°C. Once frozen, three of them were sectioned, and four samples corresponding to four different VH areas were collected: the cortical, core, and basal, which was further divided into a superior and an inferior fraction. An additional two samples were collected that were representative of the whole vitreous body. 1H-NMR spectra were acquired for twenty-three goat vitreous samples with the aim of characterizing the metabolomic signature of this biofluid and identifying whether any site-specific patterns were present. Multivariate statistical analysis (MVA) of the spectral data were carried out, including Principal Component Analysis (PCA), Hierarchical Cluster Analysis (HCA), and Partial Least Squares Discriminant Analysis (PLS-DA). A unique metabolomic signature belonging to each area was observed. The cortical area was characterized by lactate, glutamine, choline, and its derivatives, N-acetyl groups, creatine, and glycerol; the core area was characterized by glucose, acetate, and scyllo-inositol; and the basal area was characterized by branched-chain amino acids (BCAA), betaine, alanine, ascorbate, lysine, and myo-inositol. We propose a speculative approach on the topographic role of these molecules that are mainly responsible for metabolic differences among the as-identified areas. 1H-NMR-based metabolomic analysis has shown to be an important tool for investigating the VH. In particular, this approach was able to assess in the samples here analyzed the presence of different functional areas on the basis of a different metabolite distribution. © 2014 Locci et al

The union-closed set conjecture is true

We prove that the conjecture made by Peter Frankl in the late 1970s is true. In other words for every finite union-closed family which contains a non?empty set, there is an element that belongs to at least half of its

DART: the distributed agent based retrieval toolkit

The technology of search engines is evolving from indexing and classification of web resources based on keywords to more sophisticated techniques which take into account the meaning and the context of textual information and usage. Replying to query, commercial search engines face the user requests with a large amount of results, mostly useless or only partially related to the request; the subsequent refinement, operated downloading and examining as much pages as possible and simply ignoring whatever stays behind the first few pages, is left up to the user. Furthermore, architectures based on centralized indexes, allow commercial search engines to control the advertisement of online information, in contrast to P2P architectures that focus the attention on user requirements involving the end user in search engine maintenance and operation. To address such wishes, new search engines should focus on three key aspects: semantics, geo-referencing, collaboration/distribution. Semantic analysis lets to increase the results relevance. The geo-referencing of catalogued resources allows contextualisation based on user position. Collaboration distributes storage, processing, and trust on a world-wide network of nodes running on users’ computers, getting rid of bottlenecks and central points of failures. In this paper, we describe the studies, the concepts and the solutions developed in the DART project to introduce these three key features in a novel search engine architecture

A collaborative, semantic and context-aware search engine

Search engines help people to find information in the largest public knowledge system of the world: the Web. Unfortunately its size makes very complex to discover the right information. The users are faced lots of useless results forcing them to select one by one the most suitable. The new generation of search engines evolve from keyword-based indexing and classification to more sophisticated techniques considering the meaning, the context and the usage of information. We argue about the three key aspects: collaboration, geo-referencing and semantics. Collaboration distributes storage, processing and trust on a world-wide network of nodes running on users’ computers, getting rid of bottlenecks and central points of failures. The geo-referencing of catalogued resources allows contextualisation based on user position. Semantic analysis lets to increase the results relevance. In this paper, we expose the studies, the concepts and the solutions of a research project to introduce these three key features in a novel search engine architecture.213-21

A Fatal Case of Metastatic Pulmonary Calcification during the Puerperium

We present an unusual case of a fatal respiratory failure in a young woman developed two weeks after she gave birth at home. Circumstantial and clinical features of the case were strongly suggestive for a ‘classical’ septic origin of the respiratory symptoms. Autopsy, together with histopathological and immunohistochemical analyses allowed demonstrating a massive calcium redistribution consisting of an important osteolysis, especially from cranial bones and abnormal accumulation in lungs and other organs. Such physiopathology was driven by a primary hyperparathyroidism secondary to a parathyroid carcinoma as demonstrated by immunohistochemistry. This very rare case is furthermore characterised by a regular pregnancy course, ended with the birth of a healthy new-born. A complex interaction between pregnancy physiology and hyperparathyroidism might be hypothesised, determining the discrepancy between the relative long period of wellness and the tumultuous cascade occurred in the puerperium