The Messenger Sector of SUSY Flavour Models and Radiative Breaking of Flavour Universality

The flavour messenger sectors and their impact on the soft SUSY breaking terms are investigated in SUSY flavour models. In the case when the flavour scale M is below the SUSY breaking mediation scale M_S, the universality of soft terms, even if assumed at M_S, is radiatively broken. We estimate this effect in a broad class of models. In the CKM basis that effect gives flavour off-diagonal soft masses comparable to the tree-level estimate based on the flavour symmetry.Comment: 24 pages, 3 figures. v3: minor changes in the text, typos corrected, version accepted for publication in JHE

Flavor Symmetries and The Problem of Squark Degeneracy

If supersymmetry exists at low energies, it is necessary to understand why the squark spectrum exhibits sufficient degeneracy to suppress flavor changing neutral currents. In this note, we point out that gauged horizontal symmetries can yield realistic quark mass matrices, while at the same time giving just barely enough squark degeneracy to account for neutral $K$-meson phenomenology. This approach suggests likely patterns for squark masses, and indicates that there could be significant supersymmetric contributions to $B-\bar{B}$ and $D-\bar{D}$ mixing and CP violation in the $K$ and $B$ systems.Comment: preprint SCIPP 93/04,SLAC-PUB-6147, 14 pages, 4 tables included; uses macro package TABLES.TEX and phyzzx forma

General Aspects of Tree Level Gauge Mediation

Tree level gauge mediation (TGM) may be considered as the simplest way to communicate supersymmetry breaking: through the tree level renormalizable exchange of heavy gauge messengers. We study its general structure, in particular the general form of tree level sfermion masses and of one loop, but enhanced, gaugino masses. This allows us to set up general guidelines for model building and to identify the hypotheses underlying the phenomenological predictions. In the context of models based on the "minimal" gauge group SO(10), we show that only two "pure" embeddings of the MSSM fields are possible using $d< 120$ representations, each of them leading to specific predictions for the ratios of family universal sfermion masses at the GUT scale, $m^2_{\bar{5}} = 2 m^2_{10}$ or $m^2_{\bar{5}} = (3/4) m^2_{10}$ (in SU(5) notation). These ratios are determined by group factors and are peculiar enough to make this scheme testable at the LHC. We also discuss three possible approaches to the $\mu$-problem, one of them distinctive of TGM.Comment: 37 pages, 2 figure

The Somatosensory Link in Fibromyalgia: Functional Connectivity of the Primary Somatosensory Cortex Is Altered by Sustained Pain and Is Associated With Clinical/Autonomic Dysfunction

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111091/1/art39043.pd

Universal Constraints on Low-Energy Flavour Models

It is pointed out that in a general class of flavour models one can identify certain universally present FCNC operators, induced by the exchange of heavy flavour messengers. Their coefficients depend on the rotation angles that connect flavour and fermion mass basis. The lower bounds on the messenger scale are derived using updated experimental constraints on the FCNC operators. The obtained bounds are different for different operators and in addition they depend on the chosen set of rotations. Given the sensitivity expected in the forthcoming experiments, the present analysis suggests interesting room for discovering new physics. As the highlights emerge the leptonic processes, $\mu\rightarrow e\gamma$, $\mu\rightarrow eee$ and $\mu\rightarrow e$ conversion in nuclei.Comment: 18 pages, 3 figures; v2 matches published versio

A New Model for Fermion Masses in Supersymmetric Grand Unified Theories

We present a simple model for fermion mass matrices and quark mixing in the context of supersymmetric grand unified theories and show its agreement with experiment. Our model realizes the GUT mass relations $m_d=3m_e$, $m_s= m_\mu/3$, $m_b=m_\tau$ in a new way and is easily consistent with values of $m_t$ suggested by MSSM fits to LEP data.Comment: Latex, 8 p., ITP-SB-93-37 (revised version contains minor changes in some wording and citations; no changes in analytic or numerical results.

Evidence of two deeply divergent co-existing mitochondrial genomes in the Tuatara reveals an extremely complex genomic organization

Animal mitochondrial genomic polymorphism occurs as low-level mitochondrial heteroplasmy and deeply divergent co-existing molecules. The latter is rare, known only in bivalvian mollusks. Here we show two deeply divergent co-existing mt-genomes in a vertebrate through genomic sequencing of the Tuatara (Sphenodon punctatus), the sole-representative of an ancient reptilian Order. The two molecules, revealed using a combination of short-read and long-read sequencing technologies, differ by 10.4% nucleotide divergence. A single long-read covers an entire mt-molecule for both strands. Phylogenetic analyses suggest a 7–8 million-year divergence between genomes. Contrary to earlier reports, all 37 genes typical of animal mitochondria, with drastic gene rearrangements, are confirmed for both mt-genomes. Also unique to vertebrates, concerted evolution drives three near-identical putative Control Region non-coding blocks. Evidence of positive selection at sites linked to metabolically important transmembrane regions of encoded proteins suggests these two mt-genomes may confer an adaptive advantage for an unusually cold-tolerant reptile

The One Health Approach to Toxoplasmosis: Epidemiology, Control, and Prevention Strategies

One Health is a collaborative, interdisciplinary effort that seeks optimal health for people, animals, plants, and the environment. Toxoplasmosis, caused by Toxoplasma gondii, is an intracellular protozoan infection distributed worldwide, with a heteroxenous life cycle that practically affects all homeotherms and in which felines act as definitive reservoirs. Herein, we review the natural history of T. gondii, its transmission and impacts in humans, domestic animals, wildlife both terrestrial and aquatic, and ecosystems. The epidemiology, prevention, and control strategies are reviewed, with the objective of facilitating awareness of this disease and promoting transdisciplinary collaborations, integrative research, and capacity building among universities, government agencies, NGOs, policy makers, practicing physicians, veterinarians, and the general public