The Anatomy of a Spin-Off

Section 355 of the Internal Revenue Code, which specially treats certain forms of corporate reorganization, has been the constant subject of both scholarly commentary and litigation. The experience of functioning under these spin-off provisions has resulted in clarification of the law and has also raised significant questions as to its scope. The precise limits of the section remain to some extent in a state of flux and await further exposition by the courts

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion

Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes fission. Extensive morphological changes also occur as the parasite transitions from the intracellular environment to the extracellular environment. We show that treatment with the ionophore monensin causes reversible constriction of the mitochondrial outer membrane and that this effect depends on the function of the fission-related protein Fis1. We also observed that mislocalization of the endogenous Fis1 causes a dominant-negative effect that affects the morphology of the mitochondrion. As this suggests that Fis1 interacts with proteins critical for maintenance of mitochondrial structure, we performed various protein interaction trap screens. In this manner, we identified a novel outer mitochondrial membrane protein, LMF1, which is essential for positioning of the mitochondrion in intracellular parasites. Normally, while inside a host cell, the parasite mitochondrion is maintained in a lasso shape that stretches around the parasite periphery where it has regions of coupling with the parasite pellicle, suggesting the presence of membrane contact sites. In intracellular parasites lacking LMF1, the mitochondrion is retracted away from the pellicle and instead is collapsed, as normally seen only in extracellular parasites. We show that this phenotype is associated with defects in parasite fitness and mitochondrial segregation. Thus, LMF1 is necessary for mitochondrial association with the parasite pellicle during intracellular growth, and proper mitochondrial morphology is a prerequisite for mitochondrial division

Armstrong on Probabilistic Laws of Nature

D. M. Armstrong famously claims that deterministic laws of nature are contingent relations between universals and that his account can also be straightforwardly extended to irreducibly probabilistic laws of nature. For the most part, philosophers have neglected to scrutinize Armstrong’s account of probabilistic laws. This is surprising precisely because his own claims about probabilistic laws make it unclear just what he takes them to be. We offer three interpretations of what Armstrong-style probabilistic laws are, and argue that all three interpretations are incompatible either with some feature of Armstrong’s broader metaphysics or with essential features of his account of laws (or both)

Support for pro-poor agricultural development and rural poverty reduction in Eastern Cape

Official data show that a small proportion of Eastern Cape households evidently derive their main or primary income from farming. But the same data also show that the majority of households with access to small plots suitable for farming are concentrated in Eastern Cape. Furthermore, comparative analyses of standard indicators of human wellbeing and development of Eastern Cape with the rest of South Africa show that the province consistently reports worse than national average rates of poverty, food insecurity, unemployment and inequality- reaching extreme levels in rural locations. Over the medium term, higher economic growth and service-oriented sectoral change, might be inadequate to reverse this dismal track record in human well-being. In this context, this paper considers the potential of better targeted public spending on agricultural development for resource-poor small farmers to raise living standards in the Eastern Cape. According to the latest official evidence, slightly more than half a million households in Eastern Cape (representing roughly 40% of all South African households) reported that they have access to farmland- with average land size in the order of 1-1.25 ha per farmily. Interventions aimed at boosting agricultural productivity among these small producers, such as the CASP launched in 2004/05, must be better targeted to meet the needs of the intended beneficiaries.International Development,

Configuration of the Crucial Set for a Quadratic Rational Map

Let $K$ be a complete, algebraically closed non-archimedean valued field, and let $\varphi(z) \in K(z)$ have degree two. We describe the crucial set of $\varphi$ in terms of the multipliers of $\varphi$ at the classical fixed points, and use this to show that the crucial set determines a stratification of the moduli space $\mathcal{M}_2(K)$ related to the reduction type of $\varphi$. We apply this to settle a special case of a conjecture of Hsia regarding the density of repelling periodic points in the non-archimedean Julia set

Chicken or egg: financial development and economic growth in China, 1992-2004

This paper contributes to the empirical finance-growth literature by examining the relationship between financial depth, banking sector development, stock market development and economic growth in China. After an extensive survey on recent financial reforms in China, we apply Granger (non-)causality tests for non-stationary variables to examine long-run and short-run causality between economic growth and financial development. We find positive relationships between financial depth, banking sector development and growth. However, stock market development does not seem to have a positive effect on long-run economic growth.

How to Handle Assumptions in Synthesis

The increased interest in reactive synthesis over the last decade has led to many improved solutions but also to many new questions. In this paper, we discuss the question of how to deal with assumptions on environment behavior. We present four goals that we think should be met and review several different possibilities that have been proposed. We argue that each of them falls short in at least one aspect.Comment: In Proceedings SYNT 2014, arXiv:1407.493

Business cycle indexes: does a heap of data help?

Business cycle indexes are used to get a timely and frequent description of the state of the economy and its likely development in the near future. This paper discusses two methods for constructing business cycle indexes, the traditional NBER method and a recently developed dynamic factor model, and compares these methods for the euro area. The results suggest that a reliable indicator can be constructed from a limited number of series that are selected using economic logic.