2,094 research outputs found

    Smartphone Wars

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    None.Technology and Industry

    Why the iPhone Won't Last Forever and What the Government Should Do to Promote its Successor

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    Because of the overwhelming, positive response to the iPhone as compared to other smart phones, exclusive agreements between handset makers and wireless carriers have come under increasing scrutiny by regulators and lawmakers. In this paper, we document the myriad revolutions that have occurred in the mobile handset market over the past twenty years. Although casual observers have often claimed that a particular innovation was here to stay, they commonly are proven wrong by unforeseen developments in this fast-changing marketplace. We argue that exclusive agreements can play an important role in helping to ensure that another must-have device will soon come along that will supplant the iPhone, and generate large benefits for consumers. These agreements, which encourage risk taking, increase choice, and frequently lower prices, should be applauded by the government. In contrast, government regulation that would require forced sharing of a successful break-through technology is likely to stifle innovation and hurt consumer welfare.

    Addressing the Next Wave of Internet Regulation: The Case For Equal Opportunity

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    In October 2009, the Federal Communications Commission released a Notice of Proposed Rule Making in which it asked for guidance on how to convert a principle of “nondiscrimination on the Internet” into a practical rule for broadband service providers. The ultimate formulation of the nondiscrimination principle could have a significant economic effect on economic welfare in the short term and on innovation. In this paper, we explain the economics of discrimination and offer a new approach for identifying anticompetitive discrimination. Discrimination raises concerns when it interferes with what is often referred to as “equality of opportunity.” However, the Commission’s proposed nondiscrimination policy, which would limit the ability of service providers and content providers to contract on terms that (1) are mutually agreeable to both parties, (2) are available to all prospective consumers, and (3) do not impose significantly externalities on third parties, is inimical to promoting equality of opportunity. Moreover, given the twosided nature of the Internet access market, a blanket rule forbidding broadband service providers from offering quality of service to content providers (and charging for it) would likely harm endusers and certain content providers.

    The Need for Greater Price Transparency in the Medical Device Industry: An Economic Analysis

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    Proposed legislation seeks to impose price transparency in the health care industry as a remedy for increasing medical device prices. This paper analyzes previous attempts to mandate similar price-disclosure rules in a variety of industries. We identify the economic conditions under which mandatory price disclosure is likely to generate substantial benefits and costs. Applying these conditions, we conclude that mandatory price disclosure for implantable devices is unlikely to pass a benefit-cost test.

    Determination of lunar ilmentite abundances from remotely sensed data

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    The mapping of ilmenite on the surface of the moon is a necessary precursor to the investigation of prospective lunar base sites. Telescopic observations of the moon using a variety of narrow bandpass optical interference filters are being performed as a preliminary means of achieving this goal. Specifically, ratios of images obtained using filters centered at 0.40 and 0.56 microns provide quantitative estimates of TiO2 abundances. Analysis of preliminary distribution maps of TiO2 concentrations allows identification of specific high-Ti areas. Investigations of these areas using slit spectra in the range 0.03 to 0.85 microns are underway to search for discrete spectral signatures attributable to ilmenite

    Predicting the effectiveness of hepatitis C virus neutralizing antibodies by bioinformatic analysis of conserved epitope residues using public sequence data

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    Hepatitis C virus (HCV) is a global health issue. Although direct-acting antivirals are available to target HCV, there is currently no vaccine. The diversity of the virus is a major obstacle to HCV vaccine development. One approach toward a vaccine is to utilize a strategy to elicit broadly neutralizing antibodies (bNAbs) that target highly-conserved epitopes. The conserved epitopes of bNAbs have been mapped almost exclusively to the E2 glycoprotein. In this study, we have used HCV-GLUE, a bioinformatics resource for HCV sequence data, to investigate the major epitopes targeted by well-characterized bNAbs. Here, we analyze the level of conservation of each epitope by genotype and subtype and consider the most promising bNAbs identified to date for further study as potential vaccine leads. For the most conserved epitopes, we also identify the most prevalent sequence variants in the circulating HCV population. We examine the distribution of E2 sequence data from across the globe and highlight regions with no coverage. Genotype 1 is the most prevalent genotype worldwide, but in many regions, it is not the dominant genotype. We find that the sequence conservation data is very encouraging; several bNAbs have a high level of conservation across all genotypes suggesting that it may be unnecessary to tailor vaccines according to the geographical distribution of genotypes

    III. Comparison of the findings of the two studies

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67190/2/10.1177_002200276400800407.pd

    Texas Forestry Paper No. 11

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    A reconnaissance level system for planning and environmental impact analysishttps://scholarworks.sfasu.edu/texas_forestry_papers/1022/thumbnail.jp
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