Food supply chain consequences of new responses to livestock epidemics

This article studies supply chain consequences from applying the new-more socially acceptable -strategy of emergency vaccination instead of the large-scale killing of healthy animals for controlling livestock epidemics. We consider an outbreak of foot and mouth disease in a densely populated livestock area of the Netherlands. From an epidemiological perspective, simulation results show that emergency vaccination significantly reduces the size of an epidemic, both in terms of the length of an outbreak and in the number of animals killed. However, in a worst-case situation, not destroying the vaccinated animals after the end of the epidemic leads to additional consequential losses for food supply chains involved of about Euro 200 million. A business case illustrates that the exact size of these losses depends on specific supply volumes and marketing strategies. Calculations provide a basis for addressing cost sharing issues and loss reducing opportunities of new responses to livestock epidemics.livestock epidemics, financial impact, consumer acceptance, Food Consumption/Nutrition/Food Safety,

Development of a Freight Demand Model with an Application to California

ABSTRACTThis paper discusses the disaggregation of the Federal Highway Administration's Freight Analysis Framework (FAF) database (version 3.0) on freight origin-destination data and the development of linear regression equations to describe the relationships between commodity-based freight trip productions/attractions to specific economic variables. Instead of generating a production/attraction equation for each commodity, commodities are grouped in certain ways to simplify model development and application. We consider three grouping methods and two model selection criteria (with and without intercepts), which are compared in terms of goodness of fit with two data sets (FAF versions 2.0 and 3.0). Furthermore, the freight generation models are validated using county-level economic data in California and applied to predict year 2015 commodity outputs. The results of this study can help city, county, metropolitan and state level planning agencies develop their own customized freight demand generation models without performing costly large-scale surveys

The t-median function on graphs

A median of a sequence pi = x1, x2, … , xk of elements of a finite metric space (X, d ) is an element x for which ∑ k, i=1 d(x, xi) is minimum. The function M with domain the set of all finite sequences on X and defined by M(pi) = {x: x is a median of pi} is called the median function on X, and is one of the most studied consensus functions. Based on previous characterizations of median sets M(pi), a generalization of the median function is introduced and studied on various graphs and ordered sets. In addition, new results are presented for median graphs

An ADER discontinuous Galerkin method on moving meshes for Liouville's equation of geometrical optics

Liouville's equation describes light propagation through an optical system. It governs the evolution of an energy distribution on phase space. This energy distribution is discontinuous across optical interfaces. Curved optical interfaces manifest themselves as moving boundaries on phase space. In this paper, an ADER discontinuous Galerkin (DG) method on a moving mesh is applied to solve Liouville's equation. In the ADER approach a temporal Taylor series is computed by replacing temporal derivatives with spatial derivatives using the Cauchy-Kovalewski procedure. The result is a fully discrete explicit scheme of arbitrary high order of accuracy. A moving mesh is not sufficient to be able to solve Liouville's equation numerically for the optical systems considered in this article. To that end, we combine the scheme with a new method we refer to as sub-cell interface method. When dealing with optical interfaces in phase space, non-local boundary conditions arise. These are incorporated in the DG method in an energy-preserving manner. Numerical experiments validate energy-preservation up to machine precision and show the high order of accuracy. Furthermore, the DG method is compared to quasi-Monte Carlo ray tracing for two examples showing that the DG method yields better accuracy in the same amount of computational time.</p

Sintered Hydroxyapatite Ceramic for Wear Studies

A sintered hydroxyapatite (HAP) ceramic for use in wear studies was prepared from a commerical tricalcium phosphate. The sintered HAP had physical properties close to those of human enamel. The coefficient of friction and wear of the sintered HAP ceramic as characterized by tangential force, track width, and surface failure data, approximated those of human enamel.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67948/2/10.1177_00220345780570070401.pd

An entangled two photon source using biexciton emission of an asymmetric quantum dot in a cavity

A semiconductor based scheme has been proposed for generating entangled photon pairs from the radiative decay of an electrically-pumped biexciton in a quantum dot. Symmetric dots produce polarisation entanglement, but experimentally-realised asymmetric dots produce photons entangled in both polarisation and frequency. In this work, we investigate the possibility of erasing the `which-path' information contained in the frequencies of the photons produced by asymmetric quantum dots to recover polarisation-entangled photons. We consider a biexciton with non-degenerate intermediate excitonic states in a leaky optical cavity with pairs of degenerate cavity modes close to the non-degenerate exciton transition frequencies. An open quantum system approach is used to compute the polarisation entanglement of the two-photon state after it escapes from the cavity, measured by the visibility of two-photon interference fringes. We explicitly relate the two-photon visibility to the degree of Bell-inequality violation, deriving a threshold at which Bell-inequality violations will be observed. Our results show that an ideal cavity will produce maximally polarisation-entangled photon pairs, and even a non-ideal cavity will produce partially entangled photon pairs capable of violating a Bell-inequality.Comment: 16 pages, 10 figures, submitted to PR

Diagnosis of childhood tuberculosis and host RNA expression in Africa

Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV

Rapid Identification of a Scalable Catalyst for the Asymmetric Hydrogenation of a Sterically Demanding Aryl Enamide

High throughput screening was used to find a cost-effective and scalable catalyst for the asymmetric hydrogenation of a sterically demanding enamide as an intermediate towards a new potent melanocortin receptor agonist useful in the treatment of obesity. Lessons drawn from the testing of a first library of 96 chiral monodentate phosphoramidites led to the design of a second focused library of 16 chiral ligands, allowing the discovery of a new efficient catalyst. This catalyst was based on rhodium and a bulky monodentate phosphite ligand. The catalyst was scaled up and used in the kilogram production of the desired bulky chiral amide

Electronic transport through domain walls in ferromagnetic nanowires: Co-existence of adiabatic and non-adiabatic spin dynamics

We study the effect of a domain wall on the electronic transport in ferromagnetic quantum wires. Due to the transverse confinement, conduction channels arise. In the presence of a domain wall, spin up and spin down electrons in these channels become coupled. For very short domain walls or at high longitudinal kinetic energy, this coupling is weak, leads to very few spin flips, and a perturbative treatment is possible. For very long domain wall structures, the spin follows adiabatically the local magnetization orientation, suppressing the effect of the domain wall on the total transmission, but reversing the spin of the electrons. In the intermediate regime, we numerically investigate the spin-dependent transport behavior for different shapes of the domain wall. We find that the knowledge of the precise shape of the domain wall is not crucial for determining the qualitative behavior. For parameters appropriate for experiments, electrons with low longitudinal energy are transmitted adiabatically while the electrons at high longitudinal energy are essentially unaffected by the domain wall. Taking this co-existence of different regimes into account is important for the understanding of recent experiments.Comment: 10 pages, 6 figure