6,583 research outputs found
Capital from an insurance company perspective
This paper was presented at the conference "Financial services at the crossroads: capital regulation in the twenty-first century" as part of session 5, "International capital allocation at financial institutions." The conference, held at the Federal Reserve Bank of New York on February 26-27, 1998, was designed to encourage a consensus between the public and private sectors on an agenda for capital regulation in the new century.Insurance industry ; Capital ; Risk
Institutionalizing Intensive Family Preservation Services: A Strategy for Creating Staffing Standards Based on Projections of At-Risk Children from Referral Sources
In spite of new legislation and much public and professional interest, intensive family preservation service (IFPS) remains in a vulnerable position as compared to other child welfare services. This article details a method to project ideal IFPS caseloads as a function of children who are at-risk for placement by various referral sources. Using this approach, resource allocation for IFPS can be more nearly on equal ground with the traditional child welfare functions and help IFPS to assume its needed place as a core service in the child welfare continuum
Profiles of Clients: The Morris Foundation Study
During the \u2750s & \u2760s, veterinarians throughout the U.S. had more clients seeking their services than the profession could comfortably manage. The \u2770\u27s brought about a trend of decreasing client visits that particularly influenced most small animal practitioners
Perturbation Treatment of High-Energy-Electron Diffraction from Imperfect Crystals
A modified-Bloch-wave expansion is used to develop a theory of high-energy-electron diffraction from imperfect crystals. To compute these new Bloch waves one must solve a linear hyperbolic system in n unknowns. Scattering among the Bloch waves is controlled by the matrix elements of the perturbing potential, and various approximations to this scattering are discussed. The hyperbolic system is transformed to normal form; in making this transformation, the unknown functions become the plane-wave amplitudes of the Darwin representation. The normal form reveals the region of determinacy of the system: a cone generated by the diffracted beams. The contraction of this cone to a line (the column approximation) is discussed in terms of the Bloch-wave scattering
Phospholipid environment alters hormone-sensitivity of the purified insulin receptor kinase
Insulin receptor kinase, affinity-purified by adsorption and elution from immobilized insulin, is stimulated 2-3-fold by insulin in detergent solution. Reconstitution of the receptor kinase into leaky vesicles containing phosphatidylcholine and phosphatidylethanolamine (1:1, w/w) by detergent removal on Sephadex G-50 results in the complete loss of receptor kinase sensitivity to activation by insulin. Insulin receptors in these vesicles also exhibit an increase in their apparent affinity for 125I-insulin (Kd = 0.12 nM versus 0.76 nM). Inclusion of 8.3-16.7% phosphatidylserine into the reconstituted vesicles restores 40-50% of the insulin-sensitivity to the receptor kinase. An elevated apparent affinity for 125I-insulin of insulin receptors in vesicles containing phosphatidylcholine and phosphatidylethanolamine is also restored to the value observed in detergent solution by the inclusion of phosphatidylserine in the reconstituted system. The effect of phosphatidylserine on insulin receptor kinase appears specific, because cholesterol, phosphatidylinositol and phosphatidic acid are all unable to restore insulin-sensitivity to the receptor kinase. Autophosphorylation sites on the insulin receptor as analysed by h.p.l.c. of tryptic 32P-labelled receptor phosphopeptides are not different for insulin receptors autophosphorylated in detergent solution or for the reconstituted vesicles in the presence or absence of phosphatidylserine. These data indicate that the phospholipid environment of insulin receptors can modulate its binding and kinase activity, and phosphatidylserine acts to restore insulin-sensitivity to the receptor kinase incorporated into phosphatidylcholine/phosphatidylethanolamine vesicles
Guide to Daily Correspondence of the Coast, Rift Valley, Central and Northeastern Provinces : Kenya National Archives
The daily correspondence of the provincial and district officers of the East Africa Protectorate and Kenya Colony were microfilmed during the 1960s as part of a cooperative project between the Kenya National Archives and Syracuse University. … This guide was prepared at Syracuse University during 1982-84 under a grant from the National Endowment for the Humanities. It is an index to the follow collections of daily correspondence:
Cost Province, 2nd series, 1894-1965: 150 reels
Central Province, 1888-1964: 71 reels (1-40, 61-91)
Rift Valley Province, 1894-1959: 61 reels
Northeastern Province, 1909-63: 46 reel
Atom Economical, One-Pot, Three-Reaction Cascade to Novel Tricyclic 2,4-Dihydro-1H-benzo[f]isochromenes
A three-step domino reaction between 1-aryl-3-hexyne-2,6-diol derivatives and aldehydes is used to construct tricyclic 1,4-dihydro-2H-benzo[f]isochromenes. The cascade is initiated by BF3·OEt2 and involves alkynyl-Prins cyclization, Friedel–Crafts alkenylation, and dehydration/aromatization to create a new, central aromatic ring and eliminate 2 equiv. of water. Electron-donating substituents on the aryl ring of the 1-aryl-3-hexyne-2,6-diols significantly increase overall yields as do electron-rich aldehyde reaction partners. For 2,4-disubstituted 2H-benzo[f]isochromene products, diastereoselectivities in the alkynyl-Prins reaction are ∼1.4 : 1 in favor of the cis-diastereomer. The stereochemistry of one cis-product was verified by X-ray crystallographic analysis and a second structure was also verified by X-ray analysis
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