3 research outputs found

    „Ich bin eine MĂ€rchenerzĂ€hlerin. So wurde ich geboren.“

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    Ist Tonke Dragt die große Neuerin der europĂ€ischen Kinder- und Jugendliteratur? Diese sicherlich provokante Frage nimmt der Sammelband in den Fokus, der auf die Tagung „'Ich bin eine MĂ€rchenerzĂ€hlerin. So wurde ich geboren'. Tonke Dragts Jugendromane – übersehene Klassiker?", die im September 2019 an der UniversitĂ€t Siegen in Kooperation mit Helma van Lierop-Debrauwer stattgefunden hat, zurĂŒckgeht

    DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

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    We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon
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