3 research outputs found
âIch bin eine MĂ€rchenerzĂ€hlerin. So wurde ich geboren.â
Ist Tonke Dragt die groĂe Neuerin der europĂ€ischen Kinder- und Jugendliteratur? Diese sicherlich provokante Frage nimmt der Sammelband in den Fokus, der auf die Tagung â'Ich bin eine MĂ€rchenerzĂ€hlerin. So wurde ich geboren'. Tonke Dragts Jugendromane â uÌbersehene Klassiker?", die im September 2019 an der UniversitĂ€t Siegen in Kooperation mit Helma van Lierop-Debrauwer stattgefunden hat, zurĂŒckgeht
DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France
We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39â3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18â0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon