Presence and rehabilitation: toward second-generation virtual reality applications in neuropsychology

Virtual Reality (VR) offers a blend of attractive attributes for rehabilitation. The most exploited is its ability to create a 3D simulation of reality that can be explored by patients under the supervision of a therapist. In fact, VR can be defined as an advanced communication interface based on interactive 3D visualization, able to collect and integrate different inputs and data sets in a single real-like experience. However, "treatment is not just fixing what is broken; it is nurturing what is best" (Seligman & Csikszentmihalyi). For rehabilitators, this statement supports the growing interest in the influence of positive psychological state on objective health care outcomes. This paper introduces a bio-cultural theory of presence linking the state of optimal experience defined as "flow" to a virtual reality experience. This suggests the possibility of using VR for a new breed of rehabilitative applications focused on a strategy defined as transformation of flow. In this view, VR can be used to trigger a broad empowerment process within the flow experience induced by a high sense of presence. The link between its experiential and simulative capabilities may transform VR into the ultimate rehabilitative device. Nevertheless, further research is required to explore more in depth the link between cognitive processes, motor activities, presence and flow

Electroweak Precision Tests in High-Energy Diboson Processes

A promising avenue to perform precision tests of the SM at the LHC is to measure differential cross-sections at high invariant mass, exploiting in this way the growth with the energy of the corrections induced by heavy new physics. We classify the leading growing-with-energy effects in longitudinal diboson and in associated Higgs production processes, showing that they can be encapsulated in four real "high-energy primary" parameters. We assess the reach on these parameters at the LHC and at future hadronic colliders, focusing in particular on the fully leptonic $WZ$ channel that appears particularly promising. The reach is found to be superior to existing constraints by one order of magnitude, providing a test of the SM electroweak sector at the per-mille level, in competition with LEP bounds. Unlike LHC Run-1 bounds, which only apply to new physics effects that are much larger than the SM in the high-energy tail of the distributions, the probe we study applies to a wider class of new physics scenarios where such large departures are not expected.Comment: 35 pages, 8 Figures, Fig.7 correcte

Profiling residential water users’ routines by eigenbehavior modelling

Developing effective demand-side management strategies is essential to meet future residential water demands, pursue water conservation, and reduce the costs for water utilities. The effectiveness of water demand management strategies relies on our understanding of water consumers’ behavior and their consumption habits and routines, which can be monitored through the deployment of smart metering technologies and the adoption of data analytics and machine learning techniques. This work contributes a novel modeling procedure, based on a combination of clustering and principal component analysis, which allows performing water users’ segmentation on the basis of their eigenbehaviors (i.e., recurrent water consumption behaviors) automatically identified from smart metered consumption data. The approach is tested against a dataset of smart metered water consumption data from 175 households in the municipality of Tegna (CH). Numerical results demonstrate the potential of the method for identifying typical profiles of water consumption, which constitute essential information to support residential water demand management

Transoral Approach to Parotid Tumors: A Review of the Literature

Different surgical techniques have been proposed for parapharyngeal space tumors, including transcervical, transparotid, trans-mandibular, infratemporal, and transoral. The choice of the correct approach depends on the size, localization and nature of the tumor. The transoral approach can be used for benign prestyloid masses, such as tumors of the deep lobe of the parotid gland. It guarantees a short hospitalization without skin scars. The narrowed access represents the main limitation of this technique. This review will summarize and analyze the current knowledge about the transoral approach to parotid lesions. Thirty-seven studies were included in a qualitative and quantitative synthesis. The novelty of this review is the quantitative analyses of the clinical data reported in the included studies

La realidad virtual como entorno fortalecedor para el cambio personal: la contribución del laboratorio de tecnología aplicada a la neuropsicología

When we exercise real choice, we gain increased control over our lives and are able to change ourselves. However for many subjects it is not easy to exercise effective choices: patients often don’t have the knowledge, skills, assertiveness, or self esteem needed. In this situation Virtual Reality (VR), an artificial reality that projects the user into a 3D space generated by the computer, may offer a critical advantage to the therapist. The enriched experience and the total level of control on its features, transform VR in an “empowering environment”, where patients can start to explore and act without feeling actually threatened. The attempt of defining, developing and testing VR tools supporting personal empowerment is the main goal of the Applied Technology for Neuro-Psychology Laboratory –ATN-P Lab– at the Istituto Auxologico Italiano. The paper describes the actual work done by the ATN-P Lab. in this area. Specifically, the open source "NeuroVR" system and its potential clinical applications –anxiety disorders, obesity and eating disorders– are presented and discussed.La capacidad de elección nos proporciona control sobre nuestras vidas y nos ofrece posibilidades de cambio. Sin embargo, para muchas personas no es fácil realizar elecciones efectivas; por ejemplo, los pacientes carecen muchas veces del conocimiento, la habilidad, la asertividad o autoestima necesarias. En esas situaciones, la realidad virtual (RV), una realidad artificial que coloca al sujeto en un espacio generado por el ordenador, puede ser para el terapeuta un recurso decisivo. La experiencia enriquecida y el control total sobre todos sus aspectos transforman la RV en un “entorno fortalecedor”, en el que los pacientes pueden comenzar a explorar y actuar sin sentirse amenazados. El principal objetivo del “Applied Technology for Neuro-Psychology Laboratory” (ATN-P Lab), perteneciente al Instituto Auxologico Italiano, es intentar definir, desarrollar y probar aplicaciones basadas en RV que faciliten el fortalecimiento personal. En este artículo se describe el trabajo que se viene realizando sobre este tema en ese laboratorio. Se presenta y discute, específicamente, el sistema de código abierto denominado “NeuroVR”, así como sus aplicaciones clínicas potenciales sobre los trastornos de ansiedad, la obesidad y los trastornos alimentarios

Experimental multiphase estimation on a chip

Multiparameter estimation is a general problem that aims at measuring unknown physical quantities, obtaining high precision in the process. In this context, the adoption of quantum resources promises a substantial boost in the achievable performances with respect to the classical case. However, several open problems remain to be addressed in the multiparameter scenario. A crucial requirement is the identification of suitable platforms to develop and experimentally test novel efficient methodologies that can be employed in this general framework. We report the experimental implementation of a reconfigurable integrated multimode interferometer designed for the simultaneous estimation of two optical phases. We verify the high-fidelity operation of the implemented device, and demonstrate quantum-enhanced performances in two-phase estimation with respect to the best classical case, post-selected to the number of detected coincidences. This device can be employed to test general adaptive multiphase protocols due to its high reconfigurability level, and represents a powerful platform to investigate the multiparameter estimation scenario.Comment: 10+7 pages, 7+4 figure

Design and Synthesis of Heterocycle‐Fused Enediyne Prodrugs Activable at Will

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