The motor function measure to study limitation of activity in children and adults with Charcot-Marie-Tooth disease

AbstractObjectiveTo study the applicability and responsiveness of the motor function measure (total score and sub-scores D1, D2 and D3) in patients with Charcot-Marie-Tooth disease.Patients and methodsTwo hundred and thirty-three patients aged 4–86 years were included in the descriptive study. Scores and sub-scores were analyzed by age and by disease subtypes. Sensitivity to change (responsiveness) was estimated in patients having had at least two evaluations with at least six months between the first and the second.ResultsMotor function measure scores decrease with age, especially sub-scores D1 and D3. There were no significant differences between the scores according to type of Charcot-Marie-Tooth disease. The scores were significantly higher for ambulatory than for non-ambulatory patients. Significant responsiveness was demonstrated only in type 2 Charcot-Marie-Tooth disease.Discussion/conclusionsOur results suggest that, especially for D1 and D3 sub-scores, the motor function measure is a reliable and valid outcome measure that can be usefully applied in longitudinal follow-up. Studies of longer duration could demonstrate its responsiveness in other Charcot-Marie-Tooth disease subtypes

The Grizzly, September 13, 1985

Freshmen Enter on High Note • U.C. Athletes are Scholars Too • New Look Campus • Letter: Enthusiastic USGA Says Be Prepared • Appointed Staff Members • Lentz Discusses Following the Leader • Grants Awarded • R.E.M. Returns With More Confidence • Squeeze Back In • Women\u27s Field Hockey Looking Strong • The Westhead is Dead • Soccer Adds Much Depth • McCloskey: Geared to do a Rambo • Welcome Back Coach • Shorts: Book Sale; Write You Are; Blanche Allen in Communications; Ursinus M.B.A. Gears up for Fall; Special Sirens; Ursinus Professor Attends Marketing Seminar; Chair of Physics Endowed; Ursinus College Receives Wellness Grant • Tannenbaum Wins Writing Honors For Second Yearhttps://digitalcommons.ursinus.edu/grizzlynews/1143/thumbnail.jp

The Grizzly, September 23, 1983

Security Measures Enacted • Rape Suspect Arrested • Union Welcomes Director • President\u27s Corner • Letters to the Editor • What to do With Your First $10,000 • Art Exhibit Opens • French Professor Earns Doctorate • Bloodmobile is Back • The New Invasion • Some People Never Give Up • Math, Science Teachers Needed • Ursinus Welcomes New Faculty • Calling All Diabetics: Wanna be a Guinea Pig? • New Look Bears Score Grid Upset • Field Hockey Off to Fine Start • Seniors Anchor U.C. Soccer • Sports Profilehttps://digitalcommons.ursinus.edu/grizzlynews/1101/thumbnail.jp

The Grizzly, April 6, 1984

Loyalty Fund Phon-a-thon, Successful • Parsons Re-elected VP of Historical Society • Nagy\u27s Stellar Lecture • McQuaid Presents Views on Candidates • Letters to the Editor: Fraternities Help to Combat Apathy; Bubble World ; UC Social Life Needs Help; Pledging Not Destructive; Pledging Enhances Development; To Ban Pledging not a Positive Aspect; In Memory of Zeta Chi; Pledging to Expand Socially • Patrol Pattern Changed, Woman is Assaulted • The Limerick Syndrome: What Would UC do? • Mardi Gras Ball Declared Success • Changing Picture of Health in \u2780\u27s • Ride for Your Life! • Two Views on the Bussing Situation • Women\u27s Tennis Splits in Opening Matches • Softball Undefeated at 6-0 • Tennis Team Nets Two Victories • Denning Captures Fencing Title • Strizke, Rosenberg Qualify for Gymnastics Championship • Men\u27s Track Kicks off \u2784 Season • Men\u27s Lacrosse Thumps Bloomsburg • Hot Hitting Leads Bears Batsmen to Victories • Baseball Team Raises Record to 6-3 • Women\u27s Track Promisinghttps://digitalcommons.ursinus.edu/grizzlynews/1116/thumbnail.jp

The Grizzly, October 28, 1983

CampusBooks Speaks Out • C and C Course Offered • Zack Is Back In Bronze • Peace Rally Held • Give Us A Little Bit Of Credit • Respect Is Goal Of Liberal Education • Homecoming: A Big Success • Nobel Prize Awarded • Spirit Week Begins • The Talented Two-Some • The Stone Age is Back • Crown Royal Features Ultimate Competition • Lady Bears Prepare For Penn State Rivalry • U.C. Soccer Continues Winning Ways • Grizziles Roll Over Lebanon Valleyhttps://digitalcommons.ursinus.edu/grizzlynews/1105/thumbnail.jp

The Grizzly, September 30, 1983

Fraternities Speak Out • Media Meeting Held • Forum Series Begins • President\u27s Corner • Letters to the Editor • Student Profile: Weible on Wheels • Guitarist Plays at Ursinus • Faculty Lectures Open • Everybody\u27s Rockin\u27 • Accountants Sponsor Competition • Parsons Stars in Video • Volleyball Picks up First Win • Gone But Not Forgotten • Speech Exemption Exam to be Given • Soccer Team Seeks to Regroup for Divisional Play • Hockey Lookin\u27 Good • Bear Pack up for Strong Season • Western Maryland Bombs Bearshttps://digitalcommons.ursinus.edu/grizzlynews/1102/thumbnail.jp

The Grizzly, November 11, 1983

Tuition Hike OK\u27ed • Founder\u27s Day Celebrated • On the Air Finally • Ursinus Commemorated on Founder\u27s Day • Letters To The Editor: Credit Policy Reviewed; Coach Needed for Diving Team; No Credit for Activities • Smart People, Poor Students • Writing Help Available • Like Father, Like Son • Choir Goes German • Two Free Plays At Ursinus • The Big Event: Casino Night Comes to Ursinus • And Another Thing • Lady Bears ECAC Champs • U.C. Soccer Hosts ECAC Tourney • Grizzlies Bury Brooklyn College • Ursinus Fourth • Women\u27s Field Hockey Concludes Successful Campaignhttps://digitalcommons.ursinus.edu/grizzlynews/1107/thumbnail.jp

The Grizzly, September 14, 1984

Record Number Enter Ursinus • Town Hears College Plans • An Athlete\u27s Battle With Alcohol • News of Yesteryear • Ursinus Enters New Era of Communications • Cobbs Shows Enthusiasm for New Position • New Dean Coaches R.A.\u27s • English Moves Into New Offices • Smooth Sailing for Hockey....on a Bumpy Field • UC Soccer Wins Home Opener • Gridders Look to Be Winners • Cross Country Kicks Off \u2784 Season • Discover Philadelphia • McQuellan Leaves • Calendarhttps://digitalcommons.ursinus.edu/grizzlynews/1120/thumbnail.jp

The Grizzly, May 4, 1984

Sir Thomson to Speak at Commencement • Changes to Take Place in Student Life Office • Yatsko Wins Fellowship • UC Hosts USWLA Championship • Professor with the Quiet Manner: George Storey Retires From English • UC Students Attend Model UN • Chamber Groups to Perform • Work Snarls Traffic on Bridge • A Legend Retires as Pancoast Leaves • Union Pub a Hit • Solution for a Printing Crisis • Letters to the Editor: Suggestions for Social Life • Standeven Wins Chemistry Award • \u2784 Ruby Orders Being Taken Now • Play Simon Sez With Bobby Gold • 3 Seniors Land Top Accounting Jobs • Post Graduation Plans for Class of 1984 • Tursi Goes to Scotland • UC Discovers Charm of Trivial Pursuit • Language Honor Society Forms Local Chapter • Richter Announces Death of Dr. Rice • Students Debate Deployment of Missiles • Ursinus, A Well Kept Secret • Forum Relieves Tension • Shiatsu Cures Stress • UC Poet Writes About Amish • Final Exam Schedule Posted • Men\u27s Lacrosse Reaches Turning Point • Men\u27s Tennis Beats Wilkes, Loses to Mules • Greek Week Reveals Student Spirit • Gasser Named New Basketball Coach • Men\u27s Track Wins 2, Drop 1 for 7-3 Record • UC Fencers Place in Tournament • Softball at 14-3 • UC Field Hockey to Visit Europe • Jamison Breaks Recordhttps://digitalcommons.ursinus.edu/grizzlynews/1118/thumbnail.jp