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Skin Necrosis Distal to a Rapid Infusion Catheter: Understanding Possible Complications of Large-bore Vascular Access Devices.
Rapid infusion catheters (RICs) allow expedient conversion of peripheral intravenous (PIV) catheters to peripheral sheaths; however, little is known about potential complications. In this case, a 64-year-old male polytrauma patient had a 20-gauge PIV catheter in the right cephalic vein upsized to an 8.5 French (Fr) RIC without incident during an arrest with pulseless electrical activity (PEA). On RIC post-placement day two, the patient developed edema and ecchymosis extending from the right dorsal mid-hand to the antecubital fossa, just distal to the RIC insertion point. Compartments were soft; the volar surface (including an arterial line location), fingers, and upper arm were normal. The RIC flushed and returned blood appropriately. Ultrasound revealed a noncompressible cephalic vein either related to the catheter or thrombosis, and imaging of the hand showed an ulnar styloid fracture and a minimally displaced triquetral fracture. The RIC was removed immediately. Over the next week, the areas of ecchymosis developed bullae and then sloughed, leaving open wounds extending into the dermis. The patient later expired from unrelated causes. The area and timing of the skin necrosis were highly suspicious for a catheter-associated complication, despite the presence of the arterial line and small distal fractures. The necrosis was potentially due to thrombosis of the superficial venous outflow system, leading to congestion and skin compromise, but we found no similar reports. Alternatively, the catheter may have ruptured the vein and caused a gravity-dependent ecchymosis, but the volar surface was not impacted, and the catheter was functioning properly. The RIC may also have encroached on the arterial space, decreasing flow, but we would have expected distal hand changes. The only published reports we could find on RIC complications involved a lost guide wire, fragmentation of a catheter during placement, and a case of compartment syndrome, raising the question of whether skin necrosis is truly a rare event or simply underreported with the RIC. Although the exact causal relationship remains unknown in our case, RICs should be removed as soon as possible after immediate stabilization
Self-similar structure and experimental signatures of suprathermal ion distribution in inertial confinement fusion implosions
The distribution function of suprathermal ions is found to be self-similar
under conditions relevant to inertial confinement fusion hot-spots. By
utilizing this feature, interference between the hydro-instabilities and
kinetic effects is for the first time assessed quantitatively to find that the
instabilities substantially aggravate the fusion reactivity reduction. The ion
tail depletion is also shown to lower the experimentally inferred ion
temperature, a novel kinetic effect that may explain the discrepancy between
the exploding pusher experiments and rad-hydro simulations and contribute to
the observation that temperature inferred from DD reaction products is lower
than from DT at National Ignition Facility.Comment: Revised version accepted for publication in PRL. "Copyright (2015) by
the American Physical Society.
Design and Evaluation of a Fiber-Optic Grip Force Sensor with Compliant 3D-Printable Structure for (f)MRI Applications
Grip force sensors compatible with magnetic resonance imaging (MRI) are used in human motor control and decision-making research, providing objective and sensitive behavioral outcome measures. Commercial sensors are expensive, cover limited force ranges, rely on pneumatic force transmission that cannot detect fast force changes, or are electrically active, which increases the risk of electromagnetic interference. We present the design and evaluation of a low-cost, 3D-printed, inherently MRI-compatible grip force sensor based on a commercial intensity-based fiber-optic sensor. A compliant monobloc structure with flexible hinges transduces grip force to a linear displacement captured by the fiber-optic sensor. The structure can easily be adapted for different force ranges by changing the hinge thickness. A prototype designed for forces up to 800 N was manufactured and showed a highly linear behavior (nonlinearity of 2.37%) and an accuracy of 1.57% in a range between zero and 500 N. It can be printed and assembled within one day and for less than $300. Accurate performance was confirmed, both inside and outside a 3 T MRI scanner within a pilot study. Given its simple design allowing for customization of sensing properties and ergonomics for different applications and requirements, the proposed grip force handle offers researchers a valuable scientific tool
Assessment of ion kinetic effects in shock-driven inertial confinement fusion implosions using fusion burn imaging
The significance and nature of ion kinetic effects in D3He-filled, shock-driven inertial confinement
fusion implosions are assessed through measurements of fusion burn profiles. Over this series of
experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number,
NK) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma
conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match
measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured
the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially
resolved measurements of the fusion burn are used to examine kinetic ion transport effects in
greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional
integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison
of measured and simulated burn profiles shows that models including ion transport effects
are able to better match the experimental results. In implosions characterized by large Knudsen
numbers (NK3), the fusion burn profiles predicted by hydrodynamics simulations that exclude
ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally
observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that
includes a model of ion diffusion is able to qualitatively match the measured profile shapes.
Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the
observed trends, though further refinement of the models is needed for a more complete and
quantitative understanding of ion kinetic effects
Neutron time-of-flight measurements of charged-particle energy loss in inertial confinement fusion plasmas
Neutron spectra from secondary ^{3}H(d,n)α reactions produced by an implosion of a deuterium-gas capsule at the National Ignition Facility have been measured with order-of-magnitude improvements in statistics and resolution over past experiments. These new data and their sensitivity to the energy loss of fast tritons emitted from thermal ^{2}H(d,p)^{3}H reactions enable the first statistically significant investigation of charged-particle stopping via the emitted neutron spectrum. Radiation-hydrodynamic simulations, constrained to match a number of observables from the implosion, were used to predict the neutron spectra while employing two different energy loss models. This analysis represents the first test of stopping models under inertial confinement fusion conditions, covering plasma temperatures of k_{B}T≈1-4 keV and particle densities of n≈(12-2)×10^{24} cm^{-3}. Under these conditions, we find significant deviations of our data from a theory employing classical collisions whereas the theory including quantum diffraction agrees with our data
Terawatt, Joule-Class Pulsed THz Sources from Microchannel Targets
Production of terawatt, joule class THz radiation sources from microchannel
targets driven with 100s of joule, picosecond lasers is reported. THz sources
of this magnitude are useful for non-linear pumping of matter and for charged
particle acceleration and manipulation. Microchannel targets demonstrate
increased conversion efficiency compared to planar foil targets, with laser
energy to THz energy conversion up to 0.9 percent.Comment: 9 pages, 2 figure
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