X-ray Emission from Extragalactic Jets

This review focuses on the X-ray emission processes of extra-galactic jets on scales resolvable by the sub arcsec resolution of the Chandra X-ray Observatory. It is divided into 4 parts. The introductory chapter reviews the classical problems for jets, as well as those associated directly with the X-ray emission. Throughout this section, we deal with the dualisms of low powered radio sources versus high powered radio galaxies and quasars; synchrotron models versus inverse Compton models; and the distinction between the relativistic plasma responsible for the received radiation and the medium responsible for the transport of energy down the jet. The second part collects the observational and inferred parameters for the currently detected X-ray jets and attempts to put their relative sizes and luminosities in perspective. In part 3, we first give the relevant radio and optical jet characteristics, and then examine the details of the X-ray data and how they can be related to various jet attributes. The last section is devoted to a critique of the two non-thermal emission processes and to prospects for progress in our understanding of jets.Comment: This is a version of a review article to be published (2006 Sep) in the Annual Reviews of Astronomy and Astrophysics, vol. 44, p. 463. 8 of the 12 figures have been removed from the article and are provided as separate jpg files to conserve space. There are 38 pages remaining in the text. Complete postscript and pdf versions are available at: http://hea-www.harvard.edu/~harris/Xjetreview

GMRT 610-MHz observations of the faint radio source population – and what these tell us about the higher radio-frequency sky

We present 610-MHz Giant Metrewave Radio Telescope observations of 0.84 deg$^{2}$ of the AMI001 field (centred on 00$^{h}$23$^{m}$10$^{s}$, +31°53′) with an rms noise of 18 μJy beam$^{-1}$ in the centre of the field. A total of 955 sources are detected, and 814 are included in the source count analysis. The source counts from these observations are consistent with previous work. We have used these data to study the spectral index distribution of a sample of sources selected at 15.7 GHz from the recent deep extension to the Tenth Cambridge (10C) survey. The median spectral index, α, (where S ∝ ν$^{−α}$) between 0.08<$\textit{S}$$_{15.7GHz}$/mJy<0.2 is 0.32 ± 0.14, showing that star-forming galaxies, which have much steeper spectra, are not contributing significantly to this population. This is in contrast to several models, but in agreement with the results from the 10C ultradeep source counts; the high-frequency sky therefore continues to be dominated by radio galaxies down to S$_{15.7GHz}$ = 0.1 mJy.The GMRT is run by the National Centre for Radio Astrophysics of the Tata Institute of Fundamental Research. IHW thanks the Science and Technologies Facilities Council for a studentship. IHW and MJJ acknowledge support from the Square Kilometre Array South Africa. IHW thanks the South African Astronomical Observatory, where some of this work was carried out

The faint radio source population at 15.7 GHz-IV. The dominance of core emission in faint radio galaxies

We present 15-GHz Karl G. Jansky Very Large Array observations of a complete sample of radio galaxies selected at 15.7 GHz from the Tenth Cambridge (10C) survey. 67 out of the 95 sources (71 per cent) are unresolved in the new observations and lower-frequency radio observations, placing an upper limit on their angular size of ~2 arcsec. Thus compact radio galaxies, or radio galaxies with very faint jets, are the dominant population in the 10C survey. This provides support for the suggestion in our previous work that low-luminosity ($L<10^{25} \, \textrm{W Hz}^{-1}$) radio galaxies are core-dominated, although higher-resolution observations are required to confirm this directly. The 10C sample of compact, high-frequency selected radio galaxies is a mixture of high-excitation and low-excitation radio galaxies and displays a range of radio spectral shapes, demonstrating that they are a mixed population of objects

The faint radio source population at 15.7 GHz - II. Multi-wavelength properties

A complete, flux density limited sample of 96 faint ($> 0.5$ mJy) radio sources is selected from the 10C survey at 15.7 GHz in the Lockman Hole. We have matched this sample to a range of multi-wavelength catalogues, including SERVS, SWIRE, UKIDSS and optical data; multi-wavelength counterparts are found for 80 of the 96 sources and spectroscopic redshifts are available for 24 sources. Photometric reshifts are estimated for the sources with multi-wavelength data available; the median redshift of the sample is 0.91 with an interquartile range of 0.84. Radio-to-optical ratios show that at least 94 per cent of the sample are radio loud, indicating that the 10C sample is dominated by radio galaxies. This is in contrast to samples selected at lower frequencies, where radio-quiet AGN and starforming galaxies are present in significant numbers at these flux density levels. All six radio-quiet sources have rising radio spectra, suggesting that they are dominated by AGN emission. These results confirm the conclusions of Paper I that the faint, flat-spectrum sources which are found to dominate the 10C sample below $\sim 1$ mJy are the cores of radio galaxies. The properties of the 10C sample are compared to the SKADS Simulated Skies; a population of low-redshift starforming galaxies predicted by the simulation is not found in the observed sample.IHW acknowledges a Science and Technology Facilities Council studentship. IHW, MJ, MV acknowledge support from the Square Kilometre Array South Africa project and the South African National Research Foundation. MV is supported by the European Commission Research Executive Agency FP7-SPACE- 2013-1 Scheme (Grant Agreement 607254 - Herschel Extragalactic Legacy Project - HELP). This research has made use of the NASA/IPAC Extragalactic Database (NED) which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration. Opinions expressed and conclusions arrived at are those of the authors and not necessarily attributed to the SKA SA. We thank the anonymous referee for their helpful comments.This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/mnras/stv190

10C continued: A deeper radio survey at 15.7 GHz

We present deep 15.7-GHz observations made with the Arcminute Microkelvin Imager Large Array in two fields previously observed as part of the Tenth Cambridge (10C) survey. These observations allow the source counts to be calculated down to 0.1 mJy, a factor of five deeper than achieved by the 10C survey. The new source counts are consistent with the extrapolated fit to the 10C source count, and display no evidence for either steepening or flattening of the counts. There is thus no evidence for the emergence of a significant new population of sources (e.g. starforming) at 15.7 GHz flux densities above 0.1 mJy, the flux density level at which we expect starforming galaxies to begin to contribute. Comparisons with the de Zotti et al. model and the SKADS Simulated Sky show that they both underestimate the observed number of sources by a factor of two at this flux density level. We suggest that this is due to the flat-spectrum cores of radio galaxies contributing more significantly to the counts than predicted by the models.We thank the staff of the Mullard Radio Astronomy Observatory for maintaining and operating AMI. IHW and CR acknowledge Science and Technology Facilities Council studentships. IHW acknowledges support from the Square Kilometre Array South Africa project and the South African National Research Foundation. This research has made use of NASA’s Astrophysics Data System. We thank the referee for their careful reading of this manuscript.This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/mnras/stv296

Efficacy of an ankle orthosis with a subtalar locking system in restricting ankle kinetics and kinematics in lateral cutting

Introduction The ankle joint is the most injured joint during sports participation [1]. Ankle orthoses have been shown to be effective in reducing ankle inversion injuries and are often prescribed for rehabilitation and prevention of lateral ankle sprains. Efficacy of ankle orthoses is often assessed by comparing reduction of passive inversion ROM as well as ankle kinematics between braced and unbraced movements [2,3]. However, joint kinetic responses in lateral cutting were rarely examined. Therefore, the objective of this study was to examine the effectiveness of a new semi-rigid ankle orthosis with a subtalar joint locking mechanism in restricting ankle kinetics and kinematics during a lateral cutting movement

Social contacts and the locations in which they occur as risk factors for influenza infection

The interaction of human social behaviour and transmission is an intriguing aspect of the life cycle of respiratory viral infections. Although age-specific mixing patterns are often assumed to be the key drivers of the age-specific heterogeneity in transmission, the association between social contacts and biologically confirmed infection has not previously been tested at the individual level. We administered a questionnaire to participants in a longitudinal cohort survey of influenza in which infection was defined by longitudinal paired serology. Using a variety of statistical approaches, we found overwhelming support for the inclusion of individual age in addition to contact variables when explaining odds of infection: the best model not including age explained only 15.7% of the deviance, whereas the best model with age explained 23.6%. However, within age groups, we did observe an association between contacts, locations and infection: median numbers of contacts (or locations) reported by those infected were higher than those from the uninfected group in every age group other than the youngest. Further, we found some support for the retention of location and contact variables in addition to age in our regression models, with excess odds of infection of approximately 10% per additional 10 contacts or one location. These results suggest that, although the relationship between age and incidence of respiratory infection at the level of the individual is not driven by self-reported social contacts, risk within an age group may be.published_or_final_versio

Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China

A key observation about the human immune response to repeated exposure to influenza A is that the first strain infecting an individual apparently produces the strongest adaptive immune response. Although antibody titers measure that response, the interpretation of titers to multiple strains - from the same sera - in terms of infection history is clouded by age effects, cross reactivity and immune waning. From July to September 2009, we collected serum samples from 151 residents of Guangdong Province, China, 7 to 81 years of age. Neutralization tests were performed against strains representing six antigenic clusters of H3N2 influenza circulating between 1968 and 2008, and three recent locally circulating strains. Patterns of neutralization titers were compared based on age at time of testing and age at time of the first isolation of each virus. Neutralization titers were highest for H3N2 strains that circulated in an individual's first decade of life (peaking at 7 years). Further, across strains and ages at testing, statistical models strongly supported a pattern of titers declining smoothly with age at the time a strain was first isolated. Those born 10 or more years after a strain emerged generally had undetectable neutralization titers to that strain (<1:10). Among those over 60 at time of testing, titers tended to increase with age. The observed pattern in H3N2 neutralization titers can be characterized as one of antigenic seniority: repeated exposure and the immune response combine to produce antibody titers that are higher to more 'senior' strains encountered earlier in life. © 2012 Lessler et al.published_or_final_versio

Gene expression and matrix turnover in overused and damaged tendons

Chronic, painful conditions affecting tendons, frequently known as tendinopathy, are very common types of sporting injury. The tendon extracellular matrix is substantially altered in tendinopathy, and these changes are thought to precede and underlie the clinical condition. The tendon cell response to repeated minor injuries or “overuse” is thought to be a major factor in the development of tendinopathy. Changes in matrix turnover may also be effected by the cellular response to physical load, altering the balance of matrix turnover and changing the structure and composition of the tendon. Matrix turnover is relatively high in tendons exposed to high mechanical demands, such as the supraspinatus and Achilles, and this is thought to represent either a repair or tissue maintenance function. Metalloproteinases are a large family of enzymes capable of degrading all of the tendon matrix components, and these are thought to play a major role in the degradation of matrix during development, adaptation and repair. It is proposed that some metalloproteinase enzymes are required for the health of the tendon, and others may be damaging, leading to degeneration of the tissue. Further research is required to investigate how these enzyme activities are regulated in tendon and altered in tendinopathy. A profile of all the metalloproteinases expressed and active in healthy and degenerate tendon is required and may lead to the development of new drug therapies for these common and debilitating sports injuries

Optically Mapping Multiple Bacterial Genomes Simultaneously in a Single Run

Optical mapping of bacterial chromosomes provides an unambiguous low-resolution sequence scaffold of the entire chromosome. In comparison to some techniques, such as pulse field gel electrophoresis, cost and throughput limit the application of this technique outside of genome finishing. We have demonstrated the production of multiple bacterial maps using a single set of consumables; this significantly reduces the time and expense of map production