172 research outputs found
Strong Coupling Constant from Scaling Violations in Fragmentation Functions
We present a new determination of the strong coupling constant alpha_s
through the scaling violations in the fragmentation functions for charged
pions, charged kaons, and protons. In our fit we include the latest e+e-
annihilation data from CERN LEP1 and SLAC SLC on the Z-boson resonance and
older, yet very precise data from SLAC PEP at center-of-mass energy sqrt(s)=29
GeV. A new world average of alpha_s is given.Comment: 10 pages, 3 eps figue
Pimonidazole binding in C6 rat brain glioma: relation with lipid droplet detection
Item does not contain fulltextIn C6 rat brain glioma, we have investigated the relation between hypoxia and the presence of lipid droplets in the cytoplasm of viable cells adjacent to necrosis. For this purpose, rats were stereotaxically implanted with C6 cells. Experiments were carried out by the end of the tumour development. A multifluorescence staining protocol combined with digital image analysis was used to quantitatively study the spatial distribution of hypoxic cells (pimonidazole), blood perfusion (Hoechst 33342), total vascular bed (collagen type IV) and lipid droplets (Red Oil) in single frozen sections. All tumours (n=6) showed necrosis, pimonidazole binding and lipid droplets. Pimonidazole binding occurred at a mean distance of 114 microm from perfused vessels mainly around necrosis. Lipid droplets were principally located in the necrotic tissue. Some smaller droplets were also observed in part of the pimonidazole-binding cells surrounding necrosis. Hence, lipid droplets appeared only in hypoxic cells adjacent to necrosis, at an approximate distance of 181 microm from perfused vessels. In conclusion, our results show that severe hypoxic cells accumulated small lipid droplets. However, a 100% colocalisation of hypoxia and lipid droplets does not exist. Thus, lipid droplets cannot be considered as a surrogate marker of hypoxia, but rather of severe, prenecrotic hypoxia
Pion-Lambda-Sigma Coupling Extracted from Hyperonic Atoms
The latest measurements of the atomic level width in Sigma-hyperonic Pb atom
offer the most accurate datum in the region of low-energy Sigma-hyperon
physics. Atomic widths are due to the conversion of Sigma-nucleon into
Lambda-nucleon. In high angular momentum states this conversion is dominated by
the one-pion exchange. A joint analysis of the data of the scattering of
negative-Sigma on proton converting into a Lambda and a neutron and of the
atomic widths allows to extract a pseudovector pion-hyperon-Sigma coupling
constant of 0.048 with a statistical error of +-0.005 and a systematic one of
+-0.004. This corresponds to a pseudoscalar coupling constant of 13.3 with a
statistical uncertainty of 1.4 and a systematic one of 1.1.Comment: 12 pages, 1 figure, Use of Revtex.st
Driven Diffusion in the Two-Dimensional Lattice Coulomb Gas; A Model for Flux Flow in Superconducting Networks
We carry out driven diffusion Monte Carlo simulations of the two dimensional
classical lattice Coulomb gas in an applied uniform electric field, as a model
for vortex motion due to an applied d.c. current, in a periodic superconducting
network. A finite-size version of dynamic scaling is used to extract the
dynamic critical exponent z, and infer the non-linear response at the
transition temperature. We consider the f=0 and f=1/2 cases, corresponding to
no applied magnetic field, and to one half flux quantum per unit cell of the
network respectively.Comment: 25 pages, 7 figures (available from [email protected]),
RevTex3.0, URST12
Harmonic Sums and Mellin Transforms up to two-loop Order
A systematic study is performed on the finite harmonic sums up to level four.
These sums form the general basis for the Mellin transforms of all individual
functions of the momentum fraction emerging in the quantities of
massless QED and QCD up to two--loop order, as the unpolarized and polarized
splitting functions, coefficient functions, and hard scattering cross sections
for space and time-like momentum transfer. The finite harmonic sums are
calculated explicitly in the linear representation. Algebraic relations
connecting these sums are derived to obtain representations based on a reduced
set of basic functions. The Mellin transforms of all the corresponding Nielsen
functions are calculated.Comment: 44 pages Latex, contract number adde
Soft-core hyperon-nucleon potentials
A new Nijmegen soft-core OBE potential model is presented for the low-energy
YN interactions. Besides the results for the fit to the scattering data, which
largely defines the model, we also present some applications to hypernuclear
systems using the G-matrix method. An important innovation with respect to the
original soft-core potential is the assignment of the cut-off masses for the
baryon-baryon-meson (BBM) vertices in accordance with broken SU(3), which
serves to connect the NN and the YN channels. As a novel feature, we allow for
medium strong breaking of the coupling constants, using the model with
a Gell-Mann--Okubo hypercharge breaking for the BBM coupling. We present six
hyperon-nucleon potentials which describe the available YN cross section data
equally well, but which exhibit some differences on a more detailed level. The
differences are constructed such that the models encompass a range of
scattering lengths in the and channels. For the
scalar-meson mixing angle we obtained values to 40 degrees, which
points to almost ideal mixing angles for the scalar states. The
G-matrix results indicate that the remarkably different spin-spin terms of the
six potentials appear specifically in the energy spectra of
hypernuclei.Comment: 37 pages, 4 figure
Fast Algorithms For Josephson Junction Arrays : Bus--bars and Defects
We critically review the fast algorithms for the numerical study of
two--dimensional Josephson junction arrays and develop the analogy of such
systems with electrostatics. We extend these procedures to arrays with
bus--bars and defects in the form of missing bonds. The role of boundaries and
of the guage choice in determing the Green's function of the system is
clarified. The extension of the Green's function approach to other situations
is also discussed.Comment: Uuencoded 1 Revtex file (11 Pages), 3 Figures : Postscript Uuencode
Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas
Tumour oxygenation and vasculature are determinants for radiation treatment outcome and prognosis in patients with squamous cell carcinomas of the head and neck. In this study we visualized and quantified these factors which may provide a predictive tool for new treatments. Twenty-one patients with stage III–IV squamous cell carcinomas of the head and neck were intravenously injected with pimonidazole, a bioreductive hypoxic marker. Tumour biopsies were taken 2 h later. Frozen tissue sections were stained for vessels and hypoxia by fluorescent immunohistochemistry. Twenty-two sections of biopsies of different head and neck sites were scanned and analysed with a computerized image analysis system. The hypoxic fractions varied from 0.02 to 0.29 and were independent from T- and N-classification, localization and differentiation grade. No significant correlation between hypoxic fraction and vascular density was observed. As a first attempt to categorize tumours based on their hypoxic profile, three different hypoxia patterns are described. The first category comprised tumours with large hypoxic, but viable, areas at distances even greater than 200 μm from the vessels. The second category showed a typical band-like distribution of hypoxia at an intermediate distance (50–200 μm) from the vessels with necrosis at greater distances. The third category demonstrated hypoxia already within 50 μm from the vessels, suggestive for acute hypoxia. This method of multiparameter analysis proved to be clinically feasible. The information on architectural patterns and the differences that exist between tumours can improve our understanding of the tumour micro-environment and may in the future be of assistance with the selection of (oxygenation modifying) treatment strategies. © 2000 Cancer Research Campaig
Relativistic bound-state equations in three dimensions
Firstly, a systematic procedure is derived for obtaining three-dimensional
bound-state equations from four-dimensional ones. Unlike ``quasi-potential
approaches'' this procedure does not involve the use of delta-function
constraints on the relative four-momentum. In the absence of negative-energy
states, the kernels of the three-dimensional equations derived by this
technique may be represented as sums of time-ordered perturbation theory
diagrams. Consequently, such equations have two major advantages over
quasi-potential equations: they may easily be written down in any Lorentz
frame, and they include the meson-retardation effects present in the original
four-dimensional equation. Secondly, a simple four-dimensional equation with
the correct one-body limit is obtained by a reorganization of the generalized
ladder Bethe-Salpeter kernel. Thirdly, our approach to deriving
three-dimensional equations is applied to this four-dimensional equation, thus
yielding a retarded interaction for use in the three-dimensional bound-state
equation of Wallace and Mandelzweig. The resulting three-dimensional equation
has the correct one-body limit and may be systematically improved upon. The
quality of the three-dimensional equation, and our general technique for
deriving such equations, is then tested by calculating bound-state properties
in a scalar field theory using six different bound-state equations. It is found
that equations obtained using the method espoused here approximate the wave
functions obtained from their parent four-dimensional equations significantly
better than the corresponding quasi-potential equations do.Comment: 28 pages, RevTeX, 6 figures attached as postscript files. Accepted
for publication in Phys. Rev. C. Minor changes from original version do not
affect argument or conclusion
Charmonium Production via Fragmentation at DESY HERA
The cross section for the photoproduction of large-p_T J/psi mesons at HERA
is calculated at next-to-leading order, adopting a perturbative approach to
describe the fragmentation of charm quarks and gluons into J/psi mesons. We
treat the charm quark according to the massless factorization scheme, where it
is assumed to be one of the active flavours inside the proton and the resolved
photon. We present inclusive distributions in transverse momentum and rapidity,
including the contributions due to direct and resolved photons. The importance
of the colour-octet components of the J/psi wave function, which contribute to
the fragmentation process, is emphasized. In addition to prompt J/psi
production, we consider also the production of chi_{cJ} states followed by
radiative decays to J/psi mesons, both in the colour-singlet and colour-octet
channels.Comment: 32 pages (Latex), 12 figures (Postscript
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