761 research outputs found

    Miniature loop heat pipe with flat evaporator for cooling computer CPU

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    This paper presents an experimental investigation on a copper miniature loop heat pipe (mLHP) with a flat disk shaped evaporator, 30mm in diameter and 10-mm thick, designed for thermal control of computer microprocessors. Tests were conducted with water as the heat transfer fluid. The device was capable of transferring a heat load of 70W through a distance up to 150mm using 2-mm diameter transport lines. For a range of power applied to the evaporator, the system demonstrated very reliable startup and was able to achieve steady state without any symptoms of wick dry-out. Unlike cylindrical evaporators, flat evaporators are easy to attach to the heat source without need of any cylinder-to-plane reducer material at the interface and thus offer very low thermal resistance to the heat acquisition process. In the horizontal configuration, under air cooling, the minimum value for the mLHP thermal resistance is 0.17degC/W with the corresponding evaporator thermal resistance of 0.06degC/W. It is concluded from the outcomes of the current study that a mLHP with flat evaporator geometry can be effectively used for the thermal control of electronic equipment including notebooks with limited space and high heat flux chipsets. The results also confirm the superior heat transfer characteristics of the copper-water configuration in mLHP

    Lanthanide Spectroscopic Studies of the Dinuclear and Mg(II)-Dependent PvuII Restriction Endonuclease

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    Type II restriction enzymes are homodimeric systems that bind four to eight base pair palindromic recognition sequences of DNA and catalyze metal ion-dependent phosphodiester cleavage. While Mg(II) is required for cleavage in these enzymes, in some systems Ca(II) promotes avid substrate binding and sequence discrimination. These properties make them useful model systems for understanding the roles of alkaline earth metal ions in nucleic acid processing. We have previously shown that two Ca(II) ions stimulate DNA binding by PvuII endonuclease and that the trivalent lanthanide ions Tb(III) and Eu(III) support subnanomolar DNA binding in this system. Here we capitalize on this behavior, employing a unique combination of luminescence spectroscopy and DNA binding assays to characterize Ln(III) binding behavior by this enzyme. Upon excitation of tyrosine residues, the emissions of both Tb(III) and Eu(III) are enhanced severalfold. This enhancement is reduced by the addition of a large excess of Ca(II), indicating that these ions bind in the active site. Poor enhancements and affinities in the presence of the active site variant E68A indicate that Glu68 is an important Ln(III) ligand, similar to that observed with Ca(II), Mg(II), and Mn(II). At low micromolar Eu(III) concentrations in the presence of enzyme (10−20 μM), Eu(III) excitation 7F0 → 5D0 spectra yield one dominant peak at 579.2 nm. A second, smaller peak at 579.4 nm is apparent at high Eu(III) concentrations (150 μM). Titration data for both Tb(III) and Eu(III) fit well to a two-site model featuring a strong site (Kd = 1−3 μM) and a much weaker site (Kd ≈ 100−200 μM). Experiments with the E68A variant indicate that the Glu68 side chain is not required for the binding of this second Ln(III) equivalent; however, the dramatic increase in DNA binding affinity around 100 μM Ln(III) for the wild-type enzyme and metal-enhanced substrate affinity for E68A are consistent with functional relevance for this weaker site. This discrimination of sites should make it possible to use lanthanide substitution and lanthanide spectroscopy to probe individual metal ion binding sites, thus adding an important tool to the study of restriction enzyme structure and function

    Precipitation data and analysis

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    CER70-71DBS-EJR-MAS-JHD-VCD-HR50.May 1971.VIMHEX is an intensive program of tropical meteorological and hydrological observations taken in northeast Venezuela during the summer of 1969 to support a study of tropical atmospheric physics and the resulting effects of rainfall. The objectives of the program are to express the meso-scale weather structure in terms of the synoptic-scale envelope and to formulate the ground response to the rainfall produced by tropical weather disturbances over relatively flat tropical topography. The Volume I Hydrology Report lists all the precipitation data collected during the summer of 1969 in the study area of northeast Venezuela. Most of the precipitation data is in the form of hourly rainfall. In addition, weekly and other longer period isohyetal maps are presented for the study area. The weekly and monthly average precipitations over the drainage basins have been determined. For the summer months of July, August, and September an average of 4.8 mm of precipitation per day fell on the drainage basins. In subsequent reports, these data will be related to the hydrology and stream response of the area.VIMHEX was sponsored by the Department of Defense through its THEMIS program

    Magnetic Resonance

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    Contains research objectives and reports on three research projects

    Human Decision-Making in Multi-Agent Systems

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    In order to avoid suboptimal collective behaviors and resolve social dilemmas, researchers have tried to understand how humans make decisions when interacting with other humans or smart machines and carried out theoretical and experimental studies aimed at influencing decision-making dynamics in large populations. We identify the key challenges and open issues in the related research, list a few popular models with the corresponding results, and point out future research directions

    Investigating the topology of interacting networks - Theory and application to coupled climate subnetworks

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    Network theory provides various tools for investigating the structural or functional topology of many complex systems found in nature, technology and society. Nevertheless, it has recently been realised that a considerable number of systems of interest should be treated, more appropriately, as interacting networks or networks of networks. Here we introduce a novel graph-theoretical framework for studying the interaction structure between subnetworks embedded within a complex network of networks. This framework allows us to quantify the structural role of single vertices or whole subnetworks with respect to the interaction of a pair of subnetworks on local, mesoscopic and global topological scales. Climate networks have recently been shown to be a powerful tool for the analysis of climatological data. Applying the general framework for studying interacting networks, we introduce coupled climate subnetworks to represent and investigate the topology of statistical relationships between the fields of distinct climatological variables. Using coupled climate subnetworks to investigate the terrestrial atmosphere's three-dimensional geopotential height field uncovers known as well as interesting novel features of the atmosphere's vertical stratification and general circulation. Specifically, the new measure "cross-betweenness" identifies regions which are particularly important for mediating vertical wind field interactions. The promising results obtained by following the coupled climate subnetwork approach present a first step towards an improved understanding of the Earth system and its complex interacting components from a network perspective
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