493 research outputs found
Interkulturelle Kommunikation : Kosten und Nutzen einer Lingua franca
Die Arbeit setzt sich mit der Bedeutung der Lingua franca in schriftlicher, online geführter Kommunikation multikultureller Teams auseinander. Dabei wird untersucht, ob sich L2-Sprecher in einer online geführten Lingua-franca-Kommunikation weniger – sowie syntaktisch und inhaltlich vereinfacht – äußern. Im Blickfeld stehen auch die Fragen, ob L1-Sprecher in einer online geführten Lingua-franca-Kommunikation vermehrt kommunikative Führungsrollen übernehmen und ihre Ideen dadurch eher durchsetzen können und ob diskursive Kommunikationskompetenzen den L2-Sprechern ebenfalls Leitungsfunktionen in einer Lingua-franca-Kommunikation ermöglichen. Nach einem einführenden historischen Rückblick auf die Entwicklung des Forschungsbereichs der Interkulturellen Kommunikation wird mithilfe des methodenintegrierenden Ansatzes der Triangulation zunächst das Kommunikationsverhalten multikultureller online kommunizierender Mitarbeiter der pharmazeutischen Firma Interkult analysiert. Im Anschluss daran werden die Ergebnisse in einem kontrollierbaren Rahmen am Seminar für Deutsch als Fremdsprachenphilologie der Universität Heidelberg anhand einer empirischen Untersuchung erweitert und überprüft: 40 Studierende der Sprachgruppen Deutsch, Englisch, Französisch und Polnisch haben sich an einer Aufgabenstellung orientiert, für die sie auf einem Onlineforum über einen Zeitraum von vier Wochen sowohl in ihrer jeweiligen L1 als auch in der Lingua franca Deutsch Lösungsmöglichkeiten diskutieren sollten. Anhand der Ergebnisse werden die anfangs genannten Fragen hinsichtlich der Rolle der Lingua franca in schriftlicher, online geführter Kommunikation multikultureller Teams bearbeitet
High-spectral-resolution terahertz imaging with a quantum-cascade laser
We report on a high-spectral-resolution terahertz imaging system
operating with a multi-mode quantum-cascade laser (QCL), a fast scanning
mirror, and a sensitive Ge:Ga detector. By tuning the frequency of the QCL,
several spectra can be recorded in 1.5 s during the scan through a gas cell
filled with methanol (CH3OH). These experiments yield information about
the local absorption and the linewidth. Measurements with a faster frame
rate of up to 3 Hz allow for the dynamic observation of CH3OH gas leaking
from a terahertz-transparent tube into the evacuated cell. In addition to the
relative absorption, the local pressure is mapped by exploiting the effect of
pressure broadening
Electromagnetic actuator of a gentle pump mechanism for blood transport
The maximum operation time in blood pump applications is limited by blood damage caused by mechanical stress within the pump. To overcome this limitation, a new pumping principle is introduced. It is based on wave propagation inside a flexible tube in combination with positive displacement. The tube stimulation is generated by an electromagnetic actuator. In contrast to common roller pumps, it is possible to achieve a pumping operation without a complete tube occlusion. This ensures gentle pumping without damaging the blood cells. Our measurement of the pump curve and the trajectory of the shock head confirms the pumping
operation without complete tube occlusion
A Critical Analysis of Complications, Recurrence Rates, and Outcome in View of Tow Spinal Surgeons'Learning Curves
peer reviewedBackground and Study Objective Interlaminar full-endoscopic diskectomy is a minimally
invasive surgical alternative to microdiskectomy for the treatment of lumbar disk
herniation. The authors analyze their surgical results and learning curves during and
after the introductory phase of this surgical technique.
Patients and Methods We present a case review of 76 patients operated on using
interlaminar full-endoscopic diskectomy. We retrospectively analyzed two spinal surgeons’
learning curves in terms of operation time with respect to intraoperative blood
loss, conversion rates, complications, infections, length of hospitalization, need for
rehabilitation, recurrence rates, pain intensity, and opioid use. Patients’ functional
status and Health-related Quality of Life were assessed by follow-up questionnaires for
47 patients, using the North American Spine Society Score and the Short Form 12 in
addition to long-term pain intensity, work capacity, and patient satisfaction with the
operation.
Results A steady state of the learning curve (operation time) of an experienced spinal
surgeon was reached after 40 cases. Supervision by a more experienced surgeon can
shorten the learning curve. The rate of conversions (10%), complications (5%), and
recurrent lumbar disk herniations (28%) did not negatively affect the long-term
outcome in patients operated on before and after the learning phase. Patient satisfaction
was high.
Conclusions The rate of conversions, complications, and recurrent lumbar disk
herniations compared with microdiskectomy combined with the challenging learning
curve should be considered before surgeons adopt this procedure. Supervision by an
endoscopically experienced spinal surgeon during the introductory phase is highly
advisable.
received
Apri
A 3.5-THz, x6-Harmonic, Single-Ended Schottky Diode Mixer for Frequency Stabilization of Quantum-Cascade Lasers
Efficient and compact frequency converters are essential for frequency
stabilization of terahertz sources. In this paper, we present a 3.5-THz,
x6-harmonic, integrated Schottky diode mixer operating at room temperature. The
designed frequency converter is based on a single-ended, planar Schottky diode
with a sub-micron anode contact area defined on a suspended 2-m ultra-thin
GaAs substrate. The dc-grounded anode pad was combined with the radio frequency
E-plane probe, which resulted in an electrically compact circuit. At 200 MHz
intermediate frequency, a mixer conversion loss of about 59 dB is measured and
resulting in a 40 dB signal-to-noise ratio for phase locking 3.5-THz
quantum-cascade laser. Using a quasi-static diode model combined with
electromagnetic simulations, good agreement with the measured results was
obtained. Harmonic frequency converters without the need of cryogenic cooling
will help in the realization of highly sensitive space and air-borne heterodyne
receivers.Comment: Submitted to IEEE-TS
Observation of Atomic Oxygen in the Mesosphere and Thermosphere of Earth with the THz Heterodyne Spectrometer GREAT
Atomic oxygen governs photochemistry and energy balance of the mesosphere and lower thermosphere of the Earth. Its concentration is extremely difficult to measure with remote sensing techniques since it has only few optically active transitions. Current indirect measurements involve photochemical models and the results are not always in agreement, particularly when obtained with different instruments. In addition, altitudes above 100 km are not covered by these methods. We report on direct measurements of the 4.7-THz fine-structure transition of atomic oxygen at 4.7448 THz using the German Receiver for Astronomy at Terahertz Frequencies on board the Stratospheric Observatory for Infrared Astronomy. Our measurements agree well with atmospheric models and satellite observations below 100 km
Growth factor-mediated augmentation of long bones: evaluation of a BMP-7 loaded thermoresponsive hydrogel in a murine femoral intramedullary injection model
Background
Due to our aging population, an increase in proximal femur fractures can be expected, which is associated with impaired activities of daily living and a high risk of mortality. These patients are also at a high risk to suffer a secondary osteoporosis-related fracture on the contralateral hip. In this context, growth factors could open the field for regenerative approaches, as it is known that, i.e., the growth factor BMP-7 (bone morphogenetic protein 7) is a potent stimulator of osteogenesis. Local prophylactic augmentation of the proximal femur with a BMP-7 loaded thermoresponsive hydrogel during index surgery of an osteoporotic fracture could be suitable to reduce the risk of further osteoporosis-associated secondary fractures. The present study therefore aims to test the hypothesis if a BMP-7 augmented hydrogel is an applicable carrier for the augmentation of non-fractured proximal femurs. Furthermore, it needs to be shown that the minimally invasive injection of a hydrogel into the mouse femur is technically feasible.
Methods
In this study, male C57BL/6 mice (n = 36) received a unilateral femoral intramedullary injection of either 100 μl saline, 100 μl 1,4 Butan-Diisocyanat (BDI)-hydrogel, or 100 μl hydrogel loaded with 1 μg of bone morphogenetic protein 7. Mice were sacrificed 4 and 12 weeks later. The femora were submitted to high-resolution X-ray tomography and subsequent histological examination.
Results
Analysis of normalized CtBMD (Cortical bone mineral density) as obtained by X-ray micro-computed tomography analysis revealed significant differences depending on the duration of treatment (4 vs 12 weeks; p < 0.05). Furthermore, within different anatomically defined regions of interest, significant associations between normalized TbN (trabecular number) and BV/TV (percent bone volume) were noted. Histology indicated no signs of inflammation and no signs of necrosis and there were no cartilage damages, no new bone formations, or new cartilage tissues, while BMP-7 was readily detectable in all of the samples.
Conclusions
In conclusion, the murine femoral intramedullary injection model appears to be feasible and worth to be used in subsequent studies that are directed to examine the therapeutic potential of BMP-7 loaded BDI-hydrogel. Although we were unable to detect any significant osseous effects arising from the mode or duration of treatment in the present trial, the effect of different concentrations and duration of treatment in an osteoporotic model appears of interest for further experiments to reach translation into clinic and open new strategies of growth factor-mediated augmentation
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