Field-calibrated model of melt, refreezing, and runoff for polar ice caps : Application to Devon Ice Cap

Acknowledgments R.M.M. was supported by the Scottish Alliance for Geoscience, Environment and Society (SAGES). The field data collection contributed to the validation of the European Space Agency Cryosat mission and was supported by the Natural Sciences and Engineering Research Council, Canada, the Meteorological Service of Canada (CRYSYS program), the Polar Continental Shelf Project (an agency of Natural Resources Canada), and by UK Natural Environment Research Council consortium grant NER/O/S/2003/00620. Support for D.O.B. was provided by the Canadian Circumpolar Institute and the Climate Change Geoscience Program, Earth Sciences Sector, Natural Resources Canada (ESS contribution 20130371). Thanks are also due to the Nunavut Research Institute and the communities of Resolute Bay and Grise Fjord for permission to conduct fieldwork on Devon Ice Cap. M.J. Sharp, A. Gardner, F. Cawkwell, R. Bingham, S. Williamson, L. Colgan, J. Davis, B. Danielson, J. Sekerka, L. Gray, and J. Zheng are thanked for logistical support and field assistance during the data collection. We thank Ruzica Dadic, two other anonymous reviewers, and the Editor, Bryn Hubbard, for their helpful comments on an earlier version of this paper and which resulted in significant improvements.Peer reviewedPublisher PD

Distinguishing low frequency mutations from RT-PCR and sequence errors in viral deep sequencing data

There is a high prevalence of coronary artery disease (CAD) in patients with left bundle branch block (LBBB); however there are many other causes for this electrocardiographic abnormality. Non-invasive assessment of these patients remains difficult, and all commonly used modalities exhibit several drawbacks. This often leads to these patients undergoing invasive coronary angiography which may not have been necessary. In this review, we examine the uses and limitations of commonly performed non-invasive tests for diagnosis of CAD in patients with LBBB

Absolute Intensities of the Discrete and Continuous Absorption Bands of Oxygen Gas at 1.26 and 1.065 µ and the Radiative Lifetime of the 1Δg State of Oxygen

Laboratory measurements have been made of the absolute intensities of the discrete-line absorption band at 1.26 µ, and of the continuous bands at 1.26 and 1.065 µ in oxygen gas at pressures up to 4.3 atm. It has been shown that discrete and continuous absorptions are quite independent features, the one being a measure of the intrinsic transition probability in isolated molecules, the other of its enhancement in collision complexes. In the former the lines show significant pressure broadening, but the integral molecular absorption coefficients are constant; in the latter they are proportional to pressure and continuous absorption dominates in the 1.26-µ region at about ½ atm oxygen pressure.The radiative half-life of isolated 1Δg oxygen molecules is estimated to be 45 min, and the effect of gas pressure on the rate of decay has been predicted

Signal-to-Noise Eigenmode Analysis of the Two-Year COBE Maps

To test a theory of cosmic microwave background fluctuations, it is natural to expand an anisotropy map in an uncorrelated basis of linear combinations of pixel amplitudes --- statistically-independent for both the noise and the signal. These $S/N$-eigenmodes are indispensible for rapid Bayesian analyses of anisotropy experiments, applied here to the recently-released two-year COBE {\it dmr} maps and the {\it firs} map. A 2-parameter model with an overall band-power and a spectral tilt $\nu_{\Delta T}$ describes well inflation-based theories. The band-powers for {\it all} the {\it dmr} $53,90,31$ $a$+$b$ GHz and {\it firs} 170 GHz maps agree, $\{(1.1\pm 0.1)\times 10^{-5}\}^{1/2}$, and are largely independent of tilt and degree of (sharp) $S/N$-filtering. Further, after optimal $S/N$-filtering, the {\it dmr} maps reveal the same tilt-independent large scale features and correlation function. The unfiltered {\it dmr} $53$ $a$+$b$ index $\nu_{\Delta T}+1$ is $1.4\pm 0.4$; increasing the $S/N$-filtering gives a broad region at (1.0--1.2)$\pm$0.5, a jump to (1.4--1.6)$\pm$0.5, then a drop to 0.8, the higher values clearly seen to be driven by $S/N$-power spectrum data points that do not fit single-tilt models. These indices are nicely compatible with inflation values ($\sim$0.8--1.2), but not overwhelmingly so.Comment: submitted to Phys.Rev.Letters, 4 pages, uuencoded compressed PostScript; also bdmr2.ps.Z, via anonymous ftp to ftp.cita.utoronto.ca, cd to /pub/dick/yukawa; CITA-94-2

Complementary patterns of direct amygdala and hippocampal projections to the macaque prefrontal cortex

The projections from the amygdala and hippocampus (including subiculum and presubiculum) to prefrontal cortex were compared using anterograde tracers injected into macaque monkeys (Macaca fascicularis, Macaca mulatta). Almost all prefrontal areas were found to receive some amygdala inputs. These connections, which predominantly arose from the intermediate and magnocellular basal nucleus, were particularly dense in parts of the medial and orbital prefrontal cortex. Contralateral inputs were not, however, observed. The hippocampal projections to prefrontal areas were far more restricted, being confined to the ipsilateral medial and orbital prefrontal cortex (within areas 11, 13, 14, 24a, 32, and 25). These hippocampal projections principally arose from the subiculum, with the fornix providing the sole route. Thus, while the lateral prefrontal cortex essentially receives only amygdala inputs, the orbital prefrontal cortex receives both amygdala and hippocampal inputs, though these typically target different areas. Only in medial prefrontal cortex do direct inputs from both structures terminate in common sites. But, even when convergence occurs within an area, the projections predominantly terminate in different lamina (hippocampal inputs to layer III and amygdala inputs to layers I, II, and VI). The resulting segregation of prefrontal inputs could enable the parallel processing of different information types in prefrontal cortex

2013 National Lawyers Convention: Intellectual Property: Intellectual Property, Free Markets, and Competition Policy

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Cold hardiness and overwintering strategies of hatchlings in an assemblage of northern turtles.

Field and laboratory studies were conducted during 1989-1994 to investigate the overwintering strategies of hatching turtles representing four families native to western Nebraska. Whereas hatchling snapping turtles (Chelydra serpentina) and spiny soft-shelled turtles (Apalone spinifera) overwinter in aquatic habitats, yellow mud turtles (Kinosternon flavescens) and ornate box turtles (Terrapene ornata) burrow below the natal nest and hibernate in sandy soil. Painted turtles (Chrysemys picta) overwinter within their shallow natal nests, but this species, and T. ornata, tolerate extensive tissue freezing. Overwintering behaviors of these species are consistent with indices of physiological cold hardiness and patterns of geographic distribution. Frost commonly penetrated and persisted below 10 cm, the soil depth as which hatchling C. picta routinely hibernate. Field and laboratory data suggested that hatchling C. picta survive either by remaining super-cooled (unfrozen) or by tolerating tissue freezing, the strategy employed depending on prevailing physiological and microenvironmental conditions. Whereas relatively lower temperatures can be survived in the supercooled state, supercooling capacity may be limited via the inoculation of body fluids by environmental ice. Alternatively, wheras freeze tolerence fortuitously is promoted by ice inoculation, this strategy may be viable only at relatively high subzero temperatures. A cold-hardiness stragefy based on both survival mechanisms may promote winter survival in hatchling C. picta by conferring protection under dynamic physiological and microenvironmental conditions. Physiological cold hardiness and behavior are integrated determinants of the northern distributions of temperature region turtles