Outcomes after open and endovascular repair of non-ruptured true pancreaticoduodenal and gastroduodenal artery aneurysms associated with coeliac artery compression. A multicentre retrospective study

Objective: True aneurysms of the peri-pancreatic arcade (PDAA) have been attributed to increased collateral flow related to coeliac axis (CA) occlusion by a median arcuate ligament (MAL). Although PDAA exclusion is currently recommended, simultaneous CA release and the technique to be used are debated. The aim of this retrospective multicentre study was to compare the results of open surgical repair of true non-ruptured PDAA with release or CA bypass (group A) vs. coil embolisation of PDAA and CA stenting or laparoscopic release (group B). Methods: From January 1994 to February 2019, 57 consecutive patients (group A: 31 patients; group B: 26 patients), including 35 (61%) men (mean age 56 ± 11 years), were treated at three centres. Twenty-six patients (46%) presented with non-specific abdominal pain: 15 (48%) in group A and 11 (42%) in group B (p = .80). Results: No patient died during the post-operative period. At 30 days, all PDAAs following open repair and embolisation had been treated successfully. In group A, all CAs treated by MAL release or bypass were patent. In group B, 2/12 CA stentings failed at < 48 hours, and all MAL released by laparoscopy were successful. Median length of hospital stay was significantly greater in group A than in group B (5 vs. 3 days; p = .001). In group A, all PDAAs remained excluded. In group B, three PDAA recanalisations following embolisation were treated successfully (two redo embolisations and one open surgical resection). At six years, Kaplan–Meier estimates of freedom for PDAA recanalisation were 100% in group A, and 88% ± 6% in group B (p = .082). No PDAA ruptured during follow up. In group A, all 37 CAs treated by MAL release were patent, and one aortohepatic bypass occluded. In group B, five CAs occluded: four after stenting and the other after laparoscopic MAL release with two redo stenting and three aortohepatic bypasses. Estimates of freedom from CA restenosis/occlusion were 95% ± 3% for MAL release or visceral bypass, and 60% ± 9% for CA stenting (p = .001). Two late restenoses following CA stenting were associated with PDAA recanalisation. Conclusion: Current data suggest that open and endovascular treatment of PDAA can be performed with excellent post-operative results in both groups. However, PDAA embolisation was associated with few midterm recanalisations and CA stenting with a significant number of early and midterm failures

Leading and higher twists in the proton polarized structure function at large Bjorken x

A phenomenological parameterization of the proton polarized structure function has been developed for x > 0.02 using deep inelastic data up to ~ 50 (GeV/c)**2 as well as available experimental results on both photo- and electro-production of proton resonances. According to the new parameterization the generalized Drell-Hearn-Gerasimov sum rule is predicted to have a zero-crossing point at Q**2 = 0.16 +/- 0.04 (GeV/c)**2. Then, low-order polarized Nachtmann moments have been estimated and their Q**2-behavior has been investigated in terms of leading and higher twists for Q**2 > 1 (GeV/c)**2. The leading twist has been treated at NLO in the strong coupling constant and the effects of higher orders of the perturbative series have been estimated using soft-gluon resummation techniques. In case of the first moment higher-twist effects are found to be quite small for Q**2 > 1 (GeV/c)**2, and the singlet axial charge has been determined to be a0[10 (GeV/c)**2] = 0.16 +/- 0.09. In case of higher order moments, which are sensitive to the large-x region, higher-twist effects are significantly reduced by the introduction of soft gluon contributions, but they are still relevant at Q**2 ~ few (GeV/c)**2 at variance with the case of the unpolarized transverse structure function of the proton. Our finding suggests that spin-dependent correlations among partons may have more impact than spin-independent ones. As a byproduct, it is also shown that the Bloom-Gilman local duality is strongly violated in the region of polarized electroproduction of the Delta(1232) resonance.Comment: revised version to appear in Phys. Rev. D; extended discussion on the generalized DHG sum rul

Nonlinear feedback oscillations in resonant tunneling through double barriers

We analyze the dynamical evolution of the resonant tunneling of an ensemble of electrons through a double barrier in the presence of the self-consistent potential created by the charge accumulation in the well. The intrinsic nonlinearity of the transmission process is shown to lead to oscillations of the stored charge and of the transmitted and reflected fluxes. The dependence on the electrostatic feedback induced by the self-consistent potential and on the energy width of the incident distribution is discussed.Comment: 10 pages, TeX, 5 Postscript figure

The Effects of Resonant Tunneling on Magnetoresistance through a Q uantum Dot

The effect of resonant tunneling on magnetoresistance (MR) is studied theoretically in a double junction system. We have found that the ratio of the MR of the resonant peak current is reduced more than that of the single junction, whereas that of the valley current is enhanced depending on the change of the discrete energy-level under the change of magnetic field. We also found that the peak current-valley current (PV) ratio decreases when the junction conductance increases.Comment: 11 pages, 3 figures(mail if you need), use revtex.st

Dynamic instabilities in resonant tunneling induced by a magnetic field

We show that the addition of a magnetic field parallel to the current induces self sustained intrinsic current oscillations in an asymmetric double barrier structure. The oscillations are attributed to the nonlinear dynamic coupling of the current to the charge trapped in the well, and the effect of the external field over the local density of states across the system. Our results show that the system bifurcates as the field is increased, and may transit to chaos at large enough fields.Comment: 4 pages, 3 figures, accepted in Phys. Rev. Letter

Time Dependent Current Oscillations Through a Quantum Dot

Time dependent phenomena associated to charge transport along a quantum dot in the charge quantization regime is studied. Superimposed to the Coulomb blockade behaviour the current has novel non-linear properties. Together with static multistabilities in the negative resistance region of the I-V characteristic curve, strong correlations at the dot give rise to self-sustained current and charge oscillations. Their properties depend upon the parameters of the quantum dot and the external applied voltages.Comment: 4 pages, 3 figures; to appear in PR

Diffractive optical elements for the production of synthetic spectra

We demonstrate that computer-generated diffractive optical elements can be used to synthesize the infrared spectra of real compounds. In particular, we describe a modified phase-retrieval algorithm that we have used to design diffractive elements of this type and we present experimental results for a diffractive optic which is capable of synthesizing the infrared spectrum of HF between 3600 cm{sup -1} and 4300 cm{sup -1}. The reflection-mode diffractive optic consists of 4096 lines, each 4.5 {mu}m wide, at 16 discrete depths relative to the substrate (from 0 to 1.2 {mu}m), and was fabricated on a silicon wafer using anisotropic reactive ion-beam etching in a four-mask-level process. We propose the use of such elements to replace reference cells in a new type of correlation spectroscopy that we call {open_quotes}holographic correlation spectroscopy.{close_quotes} Storage of a large number of diffractive elements, each producing a synthetic spectrum corresponding to a different target compound, in compact disk-like format, will allow a spectrometer of this type to rapidly determine the composition of unknown samples. Further, this approach can be used to perform correlation-based measurements of hazardous or transient species, for which conventional correlation spectroscopy is impractical