Anisotropic superconducting properties of aligned MgB2 crystallites

Samples of aligned MgB2 crystallites have been prepared, allowing for the first time the direct identification of an upper critical field anisotropy Hc2^{ab}/Hc2^{c}= xi_{ab}/xi_{c} ~ 1.73; with xi_{o,ab} ~ 70 A, xi_{o,c} ~ 40 A, and a mass anisotropy ratio m_{ab}/m_{c} ~ 0.3. A ferromagnetic background signal was identified, possibly related to the raw materials purity.Comment: 4 pages, 4 figures; Revised version to appear in Phys. Rev. Let

Vacuum fluctuations of a scalar field near a reflecting boundary and their effects on the motion of a test particle

The contribution from quantum vacuum fluctuations of a real massless scalar field to the motion of a test particle that interacts with the field in the presence of a perfectly reflecting flat boundary is here investigated. There is no quantum induced dispersions on the motion of the particle when it is alone in the empty space. However, when a reflecting wall is introduced, dispersions occur with magnitude dependent on how fast the system evolves between the two scenarios. A possible way of implementing this process would be by means of an idealized sudden switching, for which the transition occurs instantaneously. Although the sudden process is a simple and mathematically convenient idealization it brings some divergences to the results, particularly at a time corresponding to a round trip of a light signal between the particle and the wall. It is shown that the use of smooth switching functions, besides regularizing such divergences, enables us to better understand the behavior of the quantum dispersions induced on the motion of the particle. Furthermore, the action of modifying the vacuum state of the system leads to a change in the particle energy that depends on how fast the transition between these states is implemented. Possible implications of these results to the similar case of an electric charge near a perfectly conducting wall are discussed.Comment: 17 pages, 8 figure

Entanglement dynamics via coherent-state propagators

The dynamical generation of entanglement in closed bipartite systems is investigated in the semiclassical regime. We consider a model of two particles, initially prepared in a product of coherent states, evolving in time according to a generic Hamiltonian, and derive a formula for the linear entropy of the reduced density matrix using the semiclassical propagator in the coherent-state representation. The formula is explicitly written in terms of quantities that define the stability of classical trajectories of the underlying classical system. The formalism is then applied to the problem of two nonlinearly coupled harmonic oscillators and the result is shown to be in remarkable agreement with the exact quantum measure of entanglement in the short-time regime. An important byproduct of our approach is a unified semiclassical formula which contemplates both the coherent-state propagator and its complex conjugate.Comment: 10 page

Translocating the blood-brain barrier using electrostatics

Copyright © 2012 Ribeiro,Domingues, Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.Mammalian cell membranes regulate homeostasis, protein activity, and cell signaling. The charge at the membrane surface has been correlated with these key events. Although mammalian cells are known to be slightly anionic, quantitative information on the membrane charge and the importance of electrostatic interactions in pharmacokinetics and pharmacodynamics remain elusive. Recently, we reported for the first time that brain endothelial cells (EC) are more negatively charged than human umbilical cord cells, using zeta-potential measurements by dynamic light scattering. Here, we hypothesize that anionicity is a key feature of the blood-brain barrier (BBB) and contributes to select which compounds cross into the brain. For the sake of comparison, we also studied the membrane surface charge of blood components—red blood cells (RBC), platelets, and peripheral blood mononuclear cells (PBMC).To further quantitatively correlate the negative zeta-potential values with membrane charge density, model membranes with different percentages of anionic lipids were also evaluated. From all the cells tested, brain cell membranes are the most anionic and those having their lipids mostly exposed, which explains why lipophilic cationic compounds are more prone to cross the blood-brain barrier.Fundação para a Ciência e Tecnologia — Ministério da Educação e Ciência (FCT-MEC, Portugal) is acknowledged for funding (including fellowships SFRH/BD/42158/2007 to Marta M.B. Ribeiro, SFRH/BD/41750/2007 to Marco M. Domingues and SFRH/BD/70423/2010 to João M. Freire) and project PTDC/QUI-BIQ/119509/2010. Marie Curie Industry-Academia Partnerships and Pathways (European Commission) is also acknowledged for funding (FP7-PEOPLE-2007-3-1-IAPP, Project 230654)