Analisis Kinerja Dinas Sosial dan Pemakaman Kotapekanbaru (Studi Kasus : Pembinaan Anak Jalanan)

Pekanbaru is the capital of Riau province who also have serious concerns about the derelict in this regard are street children. Figures existence of street children in the city of Pekanbaru is high enough to be one of the social problems in the community. Pekanbaru city government was not without effort to eradicate street children in the city of Pekanbaru. One way to conduct training to street children, it is the primary goal of the research conducted by the author. In this paper the authors study using qualitative analysis methods. While the data analysis technique used is descriptive analysis of spoken words and observable behavior of the people studied.Based on the results of research conducted and followed by analyzing the data obtained from the question and answer directly to the informant, resulting in that the views of the five substances of government functions: (1) Provision of Services, as a concept has been well formulated but they lack the facilities that support, because only 1 has a facility to conduct training. (2) setting, Pekanbaru City does not have specific regional regulation of street children, street children is only one study in Pekanbaru City Regulation No. 12 Year 2008 on the Social Order. (3) Coordination of the review has been going pretty well, it is seen from the joint raid Social Service and Pekanbaru City Cemetery with other institutions that together took to the streets. (4) Representatives, Parliament representatives of the people, has synergy with the Department of Social and Pekanbaru City Cemetery, special support from relevant Council special budget for development of street children. (5) Development, Social Services and Funeral Pekanbaru, only have one container that LBK, the last condition is far from manicured, and until the end of this research in the LBK has been no activity on social issues. Judging from the five substances, some shortcomings do Social Service and Funeral Pekanbaru City street children in foster such development activities, the construction of additional homes built, as well as the need for understanding and support of all components of both the public and the government to resolve at least reduce the problem of street children.Keywords: Performance of Social Service, Government Functions, Street Child Development

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Functions of P38 and ERK kinases in zebrafish early development

Cells communicate in multicellular organisms; by secreting and sensing signals, in order to adjust their behavior to the environment. Extracellular signals such as cytokines and growth factors bind to cell surface receptors and trigger the activation of multiple protein signal transduction cascades that mediate cellular responses such as proliferation, differentiation, apoptosis and motility. The Mitogen-activated protein kinase (MAPK) family is a group of homologous proteins forming several linear signal transduction pathways. The MAPK family is conserved among eukaryotes and most vertebrates contain at least 14 MAPKs. We are interested in the molecular mechanisms of MAPK signalling that facilitate proper development of the zebrafish embryo. The zebrafish is an excellent model to delineate MAPK associated embryonic processes. The bodyplan is completed within 24hours and within a week most organs are formed. With the current available zebrafish tools molecular mechanisms could be identified and linked to cellular processes and morphological observations. We constructed constitutive active zebrafish Erk2 mutants for identification of new signalling events. We completed expression analysis of all P38 isoforms by expression analysis of the P38_ and P38_ isoforms. We also performed a comparative study between P38_ and Erk2 MAPK in gastrulation. Finally, We addressed the role of P38_ in zebrafish angiogenesis.UBL - phd migration 201

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide

Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish

Article / Letter to editorInstituut Biologie Leide