Review of \u3cem\u3eChildhood, Youth and Social Work in Transformation: Implications for Policy and Practice.\u3c/em\u3e Lynne M. Nebell, Jeffrey J. Shook, and Janet L. Finn. Reviewed by Ann Reyes Robbins.

Book review of Lynn M. Nybell, Jeffrey J. Shook, and Janet L. Finn (Eds.), Childhood, Youth and Social Work in Transformation: Implications for Policy and Practice. New York: Columbia University Press, 2009. $60.00 hardcover

Troubled Children and Children in Trouble: Redefining the Role of the Juvenile Court in the Lives of Children

This Essay considers the emerging research in the area of dual-jurisdiction children, often referred to as crossover kids -those currently or previously involved in maltreatment proceedings who have also committed delinquent acts. Part I describes the development of the juvenile courts in the early twentieth century. Part II of this Essay questions the need to track children along one legal path or another and points to the pitfalls of providing services to some children through a criminal justice paradigm instead of treating all children through a social work paradigm. Finally, Part III advocates a redesign of the juvenile court- a return to its roots- to better enable a court to consider the needs of the whole child, in context with the needs of her/his family

Review of \u3cem\u3eResearch for Action: Cross-National Perspectives on Connecting Knowledge, Policy, and Practice for Children.\u3c/em\u3e Robert Chaskin and Jona M. Rosenfeld, Editors. Reviewed by Ann Reyes Robbins.

Book review of Robert Chaskin and Jona M. Rosenfeld (Eds.), Research for Action: Cross-National Perspectives on Connecting Knowledge, Policy, and Practice for Children. New York: Oxford University Press, 2007. $42.95 hardcover

Behcet’s disease: a review

Behcet's disease (BD) is a complex systemic vasculitis with an etiopathogenesis that remains unclear. It has a strong geographic association as well as a genetic propensity linked to the HLA-B51 factor and interactions between genetic and environmental factors. The typical age of onset is 25 to 40 years old and it is more common in men, who also have a more severe condition. Occlusive vasculitis is the hallmark of this condition, which can affect vessels of all diameters. Oral ulcers, genital ulcers, skin lesions, pathergy reaction as well as involvement of other systems and organs such as ophthalmic, neurological and vascular lesions, among others, are used to make the diagnosis. Uncontrolled neutrophil activation, activation of the humoral and cell immune systems, toxic proteins and infectious agents such as herpes simplex and streptococci are all involved in their pathophysiology. Due to the heterogeneity and several systems affected, the treatment is individualized and focused on treating each clinical manifestation

Orientation of palmitoylated CaVβ2a relative to CaV2.2 is critical for slow pathway modulation of N-type Ca2+ current by tachykinin receptor activation

The Gq-coupled tachykinin receptor (neurokinin-1 receptor [NK-1R]) modulates N-type Ca2+ channel (CaV2.2 or N channel) activity at two distinct sites by a pathway involving a lipid metabolite, most likely arachidonic acid (AA). In another study published in this issue (Heneghan et al. 2009. J. Gen Physiol. doi:10.1085/jgp.200910203), we found that the form of modulation observed depends on which CaVβ is coexpressed with CaV2.2. When palmitoylated CaVβ2a is coexpressed, activation of NK-1Rs by substance P (SP) enhances N current. In contrast, when CaVβ3 is coexpressed, SP inhibits N current. However, exogenously applied palmitic acid minimizes this inhibition. These findings suggested that the palmitoyl groups of CaVβ2a may occupy an inhibitory site on CaV2.2 or prevent AA from interacting with that site, thereby minimizing inhibition. If so, changing the orientation of CaVβ2a relative to CaV2.2 may displace the palmitoyl groups and prevent them from antagonizing AA's actions, thereby allowing inhibition even in the presence of CaVβ2a. In this study, we tested this hypothesis by deleting one (Bdel1) or two (Bdel2) amino acids proximal to the α interacting domain (AID) of CaV2.2's I–II linker. CaVβs bind tightly to the AID, whereas the rigid region proximal to the AID is thought to couple CaVβ's movements to CaV2.2 gating. Although Bdel1/β2a currents exhibited more variable enhancement by SP, Bdel2/β2a current enhancement was lost at all voltages. Instead, inhibition was observed that matched the profile of N-current inhibition from CaV2.2 coexpressed with CaVβ3. Moreover, adding back exogenous palmitic acid minimized inhibition of Bdel2/β2a currents, suggesting that when palmitoylated CaVβ2a is sufficiently displaced, endogenously released AA can bind to the inhibitory site. These findings support our previous hypothesis that CaVβ2a's palmitoyl groups directly interact with an inhibitory site on CaV2.2 to block N-current inhibition by SP

Agresión sexual a menores de edad en tiempos de pandemia por Covid-19 provincia Camaná, 2021

En el presente trabajo se plasma el análisis de investigación como en la Agresión Sexual a Menores de edad en Tiempos de Pandemia por Covid-19 Provincia Camaná, 2021, se incrementó debido al confinamiento social; este proyecto de investigación es cualitativo, basándose en teorías fundamentadas de tipo básico, utilizando métodos de entrevistas, y análisis documental, con una guía de análisis de preguntas por medio de entrevistas a especialistas relacionados al tema en materias de Derecho Penal, Derecho de Familia, Psicólogos y Jueces, obteniendo como resultado los cuales fueron analizados verazmente llegando a obtener como resultado y discusión que estos agresores deben ser sancionados drásticamente con penas severas ya que los daños causados tanto física y psicológicamente son en muchos casos irreparables considerando que se trata de menores de edad, debiendo también lograr mayor celeridad y un mejor proceso de investigación por parte del Ministerio Publico y que el estado dote de mayor infraestructura a las instituciones de justici

Building Bridges in the Clouds: Connecting Researchers and Hidden Works

The work of two researchers, Mercedes Agullo and Rita Arditti, is the raw material for the development of two projects using cloud-based turn-key solutions. The resulting digital libraries bring together primary and secondary sources to a global audience of scholars and researchers that previously could not access these valuable yet hidden scholarly works. Mercedes Agulló y Cobo is a Spanish historian who, over the course of her career, has produced important scholarly reference works in the historiography of the book, painting, sculpture, and theater. The Library at UMass Boston was approached by a faculty member in Latin American & Iberian Studies interested in providing broad access to Agulló’s extensive, though largely inaccessible, body of work. In the 1990s, Argentine-born activist and educator Rita Arditti traveled to Buenos Aires from the U.S. to interview the Abuelas (Grandmothers) of the Plaza de Mayo, a group founded in 1977 to search for children who were abducted or born into captivity during the military dictatorship that ruled Argentina from 1976 to 1983

Diagnóstico y capacitación a entidades sin ánimo de lucro. Provincia del Sumapaz, Colombia

De acuerdo con datos suministrados por la Cámara de Comercio de Bogotá sucursal Fusagasugá, en 2012 estaban registradas 926 entidades sin ánimo  de lucro de la Provincia del Sumapaz.  Por el impacto económico y social que generan en los sectores rural y urbano de la región, se realizó un estudio diagnóstico de 50 de estas  organizaciones.  En desarrollo del objetivo se utilizó el método de investigación descriptivo- analítico complementándolo con un plan de acción.  Se identificaron problemas como: la carencia de liderazgo gerencial, débil planeación estratégica, bajo nivel de innovación y producción, difícil acceso  a créditos, etc.  Como fortalezas de las entidades se determinaron: toma de decisiones de- mocráticas, sentido de pertenencia y compromiso, motivación para trabajar  en equipo.  Los resultados obtenidos se transformaron en insumo para desarrollar pro- gramas de mejoramiento y capacitación en temas requeridos, proyectados a  su fortalecimiento

Healthcare service utilization in postpartum women

Background: A low ratio of utilization of healthcare services in postpartum women may contribute to maternal deaths during the postpartum period. The maternal mortality ratio is high in the Philippines. The aim of this study was to examine the current utilization of healthcare services and the effects on the health of women in the Philippines who delivered at home. Methods: This was a cross-sectional analytical study, based on a self-administrated questionnaire, conducted from March 2015 to February 2016 in Muntinlupa, Philippines. Sixty-three postpartum women who delivered at home or at a facility were enrolled for this study. A questionnaire containing questions regarding characteristics, utilization of healthcare services, and abnormal symptoms during postpartum period was administered. To analyze the questionnaire data, the sample was divided into delivery at home and delivery at a facility. Chi-square test, Fisher’s exact test, and Mann–Whitney U test were used. Results: There were significant differences in the type of birth attendant, area of residence, monthly income, and maternal and child health book usage between women who delivered at home and those who delivered at a facility (P<0.01). There was significant difference in the utilization of antenatal checkup (P<0.01) during pregnancy, whilst there was no significant difference in utilization of healthcare services during the postpartum period. Women who delivered at home were more likely to experience feeling of irritated eyes and headaches, and continuous abdominal pain (P<0.05). Conclusion: Financial and environmental barriers might hinder the utilization of healthcare services by women who deliver at home in the Philippines. Low utilization of healthcare services in women who deliver at home might result in more frequent abnormal symptoms during postpartum