Quantum Evolution of Inhomogeneities in Curved Space

We obtain the renormalized equations of motion for matter and semi-classical gravity in an inhomogeneous space-time. We use the functional Schrodinger picture and a simple Gaussian approximation to analyze the time evolution of the $\lambda\phi^4$ model, and we establish the renormalizability of this non-perturbative approximation. We also show that the energy-momentum tensor in this approximation is finite once we consider the usual mass and coupling constant renormalizations, without the need of further geometrical counter-terms.Comment: 22 page

Literacy: A cultural influence on functional left-right differences in the inferior parietal cortex

The current understanding of hemispheric interaction is limited. Functional hemispheric specialization is likely to depend on both genetic and environmental factors. In the present study we investigated the importance of one factor, literacy, for the functional lateralization in the inferior parietal cortex in two independent samples of literate and illiterate subjects. The results show that the illiterate group are consistently more right-lateralized than their literate controls. In contrast, the two groups showed a similar degree of left-right differences in early speech-related regions of the superior temporal cortex. These results provide evidence suggesting that a cultural factor, literacy, influences the functional hemispheric balance in reading and verbal working memory-related regions. In a third sample, we investigated grey and white matter with voxel-based morphometry. The results showed differences between literacy groups in white matter intensities related to the mid-body region of the corpus callosum and the inferior parietal and parietotemporal regions (literate > illiterate). There were no corresponding differences in the grey matter. This suggests that the influence of literacy on brain structure related to reading and verbal working memory is affecting large-scale brain connectivity more than grey matter per se

Final state interaction in D+→K−π+π+D^+\to K^-\pi^+\pi^+ with KπK\pi I=1/2 and 3/2 channels

The final state interaction contribution to $D^+$ decays is computed for the $K^-\pi^+\pi^+$ channel within a light-front relativistic three-body model for the final state interaction. The rescattering process between the kaon and two pions in the decay channel is considered. The off-shell decay amplitude is a solution of a four-dimensional Bethe-Salpeter equation, which is decomposed in a Faddeev form. The projection onto the light-front of the coupled set of integral equations is performed via a quasi-potential approach. The S-wave $K\pi$ interaction is introduced in the resonant isospin $1/2$ and the non-resonant isospin $3/2$ channels. The numerical solution of the light-front tridimensional inhomogeneous integral equations for the Faddeev components of the decay amplitude is performed perturbatively. The loop-expansion converges fast, and the three-loop contribution can be neglected in respect to the two-loop results for the practical application. The dependence on the model parameters in respect to the input amplitude at the partonic level is exploited and the phase found in the experimental analysis, is fitted with an appropriate choice of the real weights of the isospin components of the partonic amplitude. The data suggests a small mixture of total isospin $5/2$ to the dominant $3/2$ one. The modulus of the unsymmetrized decay amplitude, which presents a deep valley and a following increase for $K\pi$ masses above $1.5$ GeV, is fairly reproduced. This suggests the assignment of the quantum numbers $0^+$ to the isospin 1/2 $K^*(1630)$ resonance

Periodic Anderson model with electron-phonon correlated conduction band

This paper reports dynamical mean field calculations for the periodic Anderson model in which the conduction band is coupled to phonons. Motivated in part by recent attention to the role of phonons in the $\gamma$-$\alpha$ transition in Ce, this model yields a rich and unexpected phase diagram which is of intrinsic interest. Specifically, above a critical value of the electron-phonon interaction, a first order transition with two coexisting phases develops in the temperature-hybridization plane, which terminates at a second order critical point. The coexisting phases display the familiar Kondo screened and local moment character, yet they also exhibit pronounced polaronic and bipolaronic properties, respectively.Comment: 4 pages, 6 figure

Exploring the alignment of first-year summative assessments with Bloom’s Taxonomy: A longitudinal study

The correlation between the level of difficulty of assessments, Bloom’s Taxonomy as well as pass rates of courses has been a seriously under-researched area in South Africa. In this study, we proposed the revised Bloom’s taxonomy level of difficulty index, before we examined 112 first-year 2017‒2019 final and supplementary assessment papers from the Economic and Management Sciences Faculty of a university in Western Cape. The descriptive statistics showed that these assessment papers are different in terms of duration, total marks, type of questions asked as well as pass rates. It was also found that these first-year summative assessments asked questions mainly at levels two (understand) and three (apply) of the revised Bloom’s Taxonomy. In addition, the correlation and econometric analysis did not find a strong correlation between the level of difficulty index and pass rates. Nonetheless, the above-mentioned results need to be interpreted with great caution, because strictly speaking, one should also control for differences in other characteristics (e.g., students’ personal characteristics, school characteristics and lecture attendance). To conclude, there is no explicit national policy that guides higher education institutions (HEIs) on how to use Bloom’s or any other taxonomy to assess students at the appropriate National Qualifications Framework (NQF) level. Hence, our findings suggest that there is a need for a national assessment policy framework to guide HEIs on how to assess undergraduate students at different cognitive levels as required by the NQF

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

RIG-I is a viral RNA sensor that induces the production of type I interferon (IFN) in response to infection with a variety of viruses. Modification of RIG-I with K63-linked poly-ubiquitin chains, synthesised by TRIM25, is crucial for activation of the RIG-I/MAVS signalling pathway. TRIM25 activity is targeted by influenza A virus non-structural protein 1 (NS1) to suppress IFN production and prevent an efficient host immune response. Here we present structures of the human TRIM25 coiled-coil-PRYSPRY module and of complexes between the TRIM25 coiled-coil domain and NS1. These structures show that binding of NS1 interferes with the correct positioning of the PRYSPRY domain of TRIM25 required for substrate ubiquitination and provide a mechanistic explanation for how NS1 suppresses RIG-I ubiquitination and hence downstream signalling. In contrast, the formation of unanchored K63-linked poly-ubiquitin chains is unchanged by NS1 binding, indicating that RING dimerisation of TRIM25 is not affected by NS1