Preliminary Injunctions, Excessive Entanglement, and Prior Restraints: Should Courts Treat Potential Pretrial Religious Infringement the Same as Potential Pretrial Speech Infringement?

The virtually absolute ban on prior restraints against speech is, of course, cemented in the Supreme Court’s Free Speech jurisprudence. But the doctrine may potentially apply to another important First Amendment Clause: Establishment. In free speech cases, courts almost always refuse to restrict expression prior to a determination that it is protected. This Article argues that the courts should apply the same principle in cases implicating religious liberty. First, this Article examines a case in which a district court granted a preliminary injunction in favor of a religious group, but also imposed severe restrictions on the group’s ability to practice its religion. After a discussion of the Court’s Establishment Clause case law, this Article concludes that the court-imposed restrictions amounted to unconstitutional entanglement under the Lemon test. Second, this Article considers the historical debates surrounding the First Amendment and focuses on a link between the Free Speech Clause and the Religion Clauses. Specifically, James Madison wrote that both clauses are a necessary bulwark against government coercion and suppression of minority viewpoints. Government, then, cannot advance or inhibit religion and cannot promote or suppress speech. Further, this Article surveys scholarly links between the Speech and Religion Clauses and examines the Court’s current attitude towards Free Speech and Establishment. Finally, this Article argues that, in light of history, legal doctrine, and pragmatic considerations, preliminary injunction of religious liberty deserves the same treatment as preliminary injunction of speech. Because the prior restraint doctrine would counsel against court-imposed restrictions or supervision of speech, the same principles should counsel against court-imposed restrictions against religious practice

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Audiovisual Processing is Abnormal in Parkinson\u27s Disease and Correlates with Freezing of Gait and Disease Duration

Background: Sensory and perceptual disturbances progress with disease duration in Parkinson’s disease (PD) and probably contribute to motor deficits such as bradykinesia and gait disturbances, including freezing of gait (FOG). Simple reaction time tests are ideal to explore sensory processing, as they require little cognitive processing. Multisensory integration is the ability of the brain to integrate sensory information from multiple modalities into a single coherent percept, which is crucial for complex motor tasks such as gait. 9 10 11 12 13 Objectives: The aims of this study were to: 1. Assess differences in unisensory (auditory and visual) and multisensory processing speed in people with PD and age-matched healthy controls. 2. Compare relative differences in unisensory processing in people with PD with disease duration and freezing of gait status taking into account the motor delays, which are invariably present in PD. 3. Compare relative differences in multisensory (audiovisual) processing between the PD cohort and age-matched controls. 14 15 16 17 Methods: 39 people with PD (23 with FOG) and 17 age-matched healthy controls performed a reaction time task in response to unisensory (auditory-alone, visual-alone) and multisensory (audiovisual) stimuli. 18 19 Results: The PD group were significantly slower than controls for all conditions compared with healthy controls but auditory reaction times were significantly faster than visual for the PD group only. These relative unisensory differences are correlated with disease duration and divide the PD group by FOG status, but these factors are co-dependent. Although multisensory facilitation occurs in PD, it is significantly less enhanced than in healthy controls. 20 21 22 23 Conclusion: There are significant unisensory and multisensory processing abnormalities in PD. The relative differences in unisensory processing are specific to PD progression, providing a link between these sensory abnormalities and a motor feature of PD. Sensory disturbances have previously been postulated to be central to FOG but this is the first study to predict audiovisual processing abnormalities using FOG status. The multisensory processing abnormalities are independent of disease duration and FOG status and may be a potential biomarker for the disease

Managerial challenges of publicly funded principal investigators

Principal investigators (PI) are at the nexus of university business collaborations through their leadership of funded research grants. In fulfilling their multiple roles, PIs are involved in a range of different activities, from direct scientific supervision of junior scientists, the organisation of new scientific avenues to engaging with industrial partners. With the increased impetus for public research to produce wealth through science commercialisation, research is increasingly orchestrated through programmes which seek to connect research avenues and markets. The role of PIs is of growing importance. The extent of managerial challenges encountered by scientists in the context of their PI role has not been the focus of any empirical studies. This paper examines the managerial challenges experienced by publicly funded PIs. Our study, set in the context of the Irish research system, found three foci of PI managerial challenges – project management, project adaptability and project network management

Constellation Modelling, Performance Prediction and Operations Management for the Spire Constellation

The operational complexity of managing the Spire constellation continually increases with the routine introduction of additional satellites and new capabilities. The heterogeneous nature of the satellites, payloads, and ground station configurations compounds the difficulty of strategic planning and operational scheduling. In order to efficiently operate this diverse network of assets, Spire developed a suite of bespoke constellation modeling and management tools that are designed to support existing demand and to scale for future needs. The modeling tools enable Spire to accurately simulate and optimize the performance of various constellation configurations prior to deployment. The operational tools required to harness the full potential of the constellation incorporate complex techniques in order to schedule payload operations, maximize data collection, and monitor performance. These tools are developed in a modular and scalable fashion to ensure that new capabilities, such as the introduction of inter-satellite links, can be readily integrated into the planning system. In addition to these internal tools, Spire also offers a suite of standardized APIs and user services through which both internal and external customers can seamlessly integrate payloads and software with the Spire constellation, enabling secure access to development and simulation environments, scheduling, and data pipeline tools. The constellation modeling, performance prediction, and operational management tools developed at Spire are essential to ensure efficient and optimized production in an increasingly complex system

Outcomes of recurrent laryngeal nerve injury following congenital heart surgery: A contemporary experience.

OBJECTIVE: Injury to the recurrent laryngeal nerve can lead to significant morbidity during congenital cardiac surgery. The objective is to expand on the limited understanding of the severity and recovery of this iatrogenic condition. DESIGN: A six-year retrospective review of all congenital heart operations at a single institution from January 1, 2008 to December 31, 2013 was performed. All patients with documented vocal cord paralysis on laryngoscopic examination comprised the study cohort. Evaluation of time to vocal cord recovery and need for further surgical intervention was the primary focus. RESULTS: The incidence of post-operative vocal cord paralysis was 1.1% (32 out of 3036 patients; 95% confidence interval: 0.7-1.5%). The majority were left-sided injuries (71%). Overall rate of recovery was 61% with a median time of 10 months in those who recovered, and a total follow up of 46 months. Due to feeding complications, 45% of patients required gastrostomy tube after the injury, and these patients were found to have longer duration of post-operative days of intubation (median 10 vs. 5 days, p = 0.03), ICU length of stay (50 vs. 8 days, p = 0.002), and hospital length of stay (92 vs. 41 days, p = 0.01). No pre-operative variables were identified as predictive of recovery or need for gastrostomy placement. CONCLUSION: Recurrent laryngeal nerve injury is a serious complication of congenital heart surgery that impacts post-operative morbidity, in some cases leading to a need for further intervention, in particular, gastrostomy tube placement. A prospective, multi-center study is needed to fully evaluate factors that influence severity and time to recovery

Gait Characteristics and Cognitive Function in Middle-Aged Adults With and Without Type 2 Diabetes Mellitus: Data from ENBIND

Type 2 Diabetes Mellitus (T2DM) in midlife is associated with a greater risk of dementia in later life. Both gait speed and spatiotemporal gait characteristics have been associated with later cognitive decline in community-dwelling older adults. Thus, the assessment of gait characteristics in uncomplicated midlife T2DM may be important in selecting-out those with T2DM at greatest risk of later cognitive decline. We assessed the relationship between Inertial Motion Unit (IMUs)- derived gait characteristics and cognitive function assessed via Montreal Cognitive Assessment (MOCA)/detailed neuropsychological assessment battery (CANTAB) in middle-aged adults with and without uncomplicated T2DM using both multivariate linear regression and a neural network approach. Gait was assessed under (i) normal walking, (ii) fast (maximal) walking and (iii) cognitive dual-task walking (reciting alternate letters of the alphabet) conditions. Overall, 138 individuals were recruited (n = 94 with T2DM; 53% female, 52.8 8.3 years; n = 44 healthy controls, 43% female, 51.9 8.1 years). Midlife T2DM was associated with significantly slower gait velocity on both slow and fast walks (both p \u3c 0.01) in addition to a longer stride time and greater gait complexity during normal walk (both p \u3c 0.05). Findings persisted following covariate adjustment. In analyzing cognitive performance, the strongest association was observed between gait velocity and global cognitive function (MOCA). Significant associations were also observed between immediate/delayed memory performance and gait velocity. Analysis using a neural network approach did not outperform multivariate linear regression in predicting cognitive function (MOCA) from gait velocity. Our study demonstrates the impact of uncomplicated T2DM on gait speed and gait characteristics in midlife, in addition to the striking relationship between gait characteristics and global cognitive function/memory performance in midlife. Further studies are needed to evaluate the longitudinal relationship between midlife gait characteristics and later cognitive decline, which may aid in selecting-out those with T2DM at greatest-risk for preventative interventions