1,121 research outputs found
A global disorder of imprinting in the human female germ line
Imprinted genes are expressed differently depending on whether they are carried by a chromosome of maternal or paternal origin. Correct imprinting is established by germline-specific modifications; failure of this process underlies several inherited human syndromes. All these imprinting control defects are cis-acting, disrupting establishment or maintenance of allele-specific epigenetic modifications across one contiguous segment of the genome. In contrast, we report here an inherited global imprinting defect. This recessive maternal-effect mutation disrupts the specification of imprints at multiple, non-contiguous loci, with the result that genes normally carrying a maternal methylation imprint assume a paternal epigenetic pattern on the maternal allele. The resulting conception is phenotypically indistinguishable from an androgenetic complete hydatidiform mole, in which abnormal extra-embryonic tissue proliferates while development of the embryo is absent or nearly so. This disorder offers a genetic route to the identification of trans-acting oocyte factors that mediate maternal imprint establishment
Many-body large polaron optical conductivity in SrTiNbO
Recent experimental data on the optical conductivity of niobium doped
SrTiO are interpreted in terms of a gas of large polarons with effective
coupling constant . The {theoretical approach takes into
account} many-body effects, the electron-phonon interaction with multiple
LO-phonon branches, and the degeneracy and the anisotropy of the Ti t
conduction band. {Based on the Fr\"{o}hlich interaction, the many-body
large-polaron theory} provides an interpretation for the essential
characteristics, except -- interestingly -- for the unexpectedly large
intensity of a peak at meV, of the observed optical conductivity
spectra of SrTiNbO \textit{without} any adjustment of
material parameters.Comment: to appear in Phys. Rev.
Polaronic excitations in CMR manganite films
In the colossal magnetoresistance manganites polarons have been proposed as
the charge carrier state which localizes across the metal-insulator transition.
The character of the polarons is still under debate. We present an assessment
of measurements which identify polarons in the metallic state of
La{2/3}Sr{1/3}MnO{3} (LSMO) and La{2/3}Ca{1/3}MnO{3} (LCMO) thin films. We
focus on optical spectroscopy in these films which displays a pronounced
resonance in the mid-infrared. The temperature dependent resonance has been
previously assigned to polaron excitations. These polaronic resonances are
qualitatively distinct in LSMO and LCMO and we discuss large and small polaron
scenarios which have been proposed so far. There is evidence for a large
polaron excitation in LSMO and small polarons in LCMO. These scenarios are
examined with respect to further experimental probes, specifically charge
carrier mobility (Hall-effect measurements) and high-temperature
dc-resistivity.Comment: 16 pages, 10 figure
Photoinduced IR absorption in (La(1-x)Sr(x)Mn)(1-\delta)O3: changes of the anti-Jahn-Teller polaron binding energy with doping
Photoinduced IR absorption was measured in (La(1-x)Sr(x)Mn)(1-\delta)O3. A
midinfrared peak centered at ~ 5000 cm was observed in the x=0
antiferromagnetic sample. The peak diminishes and softens as hole doping is
increased. The origin of the photoinduced absorption peak is atributted to the
photon assisted hopping of anti-Jahn-Teller polarons formed by photoexcited
charge carriers, whose binding energy decreases with increasing hole doping.
The shape of the peak indicates that the polarons are small.Comment: 5 pages, 3 figures, submitted to PR
Time evolution of the Rabi Hamiltonian from the unexcited vacuum
The Rabi Hamiltonian describes a single mode of electromagnetic radiation
interacting with a two-level atom. Using the coupled cluster method, we
investigate the time evolution of this system from an initially empty field
mode and an unexcited atom. We give results for the atomic inversion and field
occupation, and find that the virtual processes cause the field to be squeezed.
No anti-bunching occurs.Comment: 25 pages, 8 figures, RevTe
Polaronic optical absorption in electron-doped and hole-doped cuprates
Polaronic features similar to those previously observed in the photoinduced
spectra of cuprates have been detected in the reflectivity spectra of
chemically doped parent compounds of high-critical-temperature superconductors,
both -type and -type. In NdCuO these features, whose
intensities depend both on doping and temperature, include local vibrational
modes in the far infrared and a broad band centered at 1000 cm.
The latter band is produced by the overtones of two (or three) local modes and
is well described in terms of a small-polaron model, with a binding energy of
about 500 cm. Most of the above infrared features are shown to survive
in the metallic phase of NdCeCu0, BiSrCuO, and
YBaCuO, where they appear as extra-Drude peaks. The occurrence
of polarons is attributed to local modes strongly coupled to carriers, as shown
by a comparison with tunneling results.Comment: File latex, 31 p., submitted to Physical Review B. Figures may be
faxed upon reques
Unified functional network and nonlinear time series analysis for complex systems science: The pyunicorn package
We introduce the \texttt{pyunicorn} (Pythonic unified complex network and
recurrence analysis toolbox) open source software package for applying and
combining modern methods of data analysis and modeling from complex network
theory and nonlinear time series analysis. \texttt{pyunicorn} is a fully
object-oriented and easily parallelizable package written in the language
Python. It allows for the construction of functional networks such as climate
networks in climatology or functional brain networks in neuroscience
representing the structure of statistical interrelationships in large data sets
of time series and, subsequently, investigating this structure using advanced
methods of complex network theory such as measures and models for spatial
networks, networks of interacting networks, node-weighted statistics or network
surrogates. Additionally, \texttt{pyunicorn} provides insights into the
nonlinear dynamics of complex systems as recorded in uni- and multivariate time
series from a non-traditional perspective by means of recurrence quantification
analysis (RQA), recurrence networks, visibility graphs and construction of
surrogate time series. The range of possible applications of the library is
outlined, drawing on several examples mainly from the field of climatology.Comment: 28 pages, 17 figure
Conductivity of CuO-Chains: Disorder versus Electron-Phonon Coupling
The optical conductivity of the CuO-chains, a subsystem of the 1-2-3
materials, is dominated by a broad peak in the mid-infrared (eV), and a slowly falling high-frequency tail. The 1D --model is
proposed as the relevant low-energy Hamiltonian describing the intrinsic
electronic structure of the CuO-chains. However, due to charge-spin
decoupling, this model alone cannot reproduce the observed \sw. We consider
two additional scattering mechanisms: (i) Disregarding the not so crucial spin
degrees of freedom, the inclusion of strong potential disorder yields excellent
agreement with experiment, but suffers from the unreasonable value of the
disorder strength necessary for the fit. (ii) Moderately strong polaronic
electron-phonon coupling to the mode involving Cu(1)-O(4) stretching, can be
modeled within a 1D Holstein Hamiltonian of spinless fermions. Using a
variational approximation for the phonon Hilbert space, we diagonalize the
Hamiltonian exactly on finite lattices. As a result of the experimental hole
density , the chains can exhibit strong charge-density-wave (CDW)
correlations, driven by phonon-mediated polaron-polaron interactions. In the
vicinity of half filling, charge motion is identified as arising from moving
domain walls, \ie defects in the CDW. Incorporating the effect of vacancy
disorder by choosing open boundary conditions, good agreement with the
experimental spectra is found. In particular, a high-frequency tail arises as a
consequence of the polaron-polaron interactions.Comment: 42 pages, ETH-TH/93-31 (Postscript
Small and large polarons in nickelates, manganites, and cuprates
By comparing the optical conductivities of La_{1.67}Sr_{0.33}NiO_{4} (LSNO),
Sr_{1.5}La_{0.5}MnO_4 (SLMO), Nd_2CuO_{4-y} (NCO), and
Nd_{1.96}Ce_{0.04}CuO_{4} (NCCO), we have identified a peculiar behavior of
polarons in this cuprate family. While in LSNO and SLMO small polarons localize
into ordered structures below a transition temperature, in those cuprates the
polarons appear to be large, and at low T their binding energy decreases. This
reflects into an increase of the polaron radius, which may trigger coherent
transport.Comment: File latex, 15 p. incl. 4 Figs. epsf, to appear on the Journal of
Superconductivity - Proc. "Stripes 1996" - Roma Dec 199
Different DNA methylation patterns detected by the Amplified Methylation Polymorphism Polymerase Chain Reaction (AMP PCR) technique among various cell types of bulls
Background: The purpose of this study was to apply an arbitrarily primed methylation sensitive polymerase chain reaction (PCR) assay called Amplified Methylation Polymorphism Polymerase Chain Reaction (AMP PCR) to investigate the methylation profiles of somatic and germ cells obtained from Holstein bulls
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