Effect of Stabilizing Exercises and Acupuncture on Postpartum Sacroiliac Pain in Egyptian Females:A Randomized Control Trial

Background: Postpartum sacroiliac joint pain, is a serious problem for the mother, affect the ability to perform daily activities and minimize health-related quality of life. This study aimed to determine the effect of stabilizing exercises and acupuncture on postpartum sacroiliac pain. Methods: Forty multiparous women with sacroiliac joint pain (SIJP), were included, aged 25 to 35 years, BMI not exceed 30kg/m², parity less than 3 times, and delivered normally, they're assigned into two equal groups. Group (A) performed stabilizing exercises for lumbo-pelvic muscles and acupuncture. Group (B) received only acupuncture, were performed three times per week for two months (24sessions). The assessment throughout the present pain intensity (PPi) and the Oswestery disability questionnaire before and after the treatment. Results: It revealed a significant decrease in the PPi scores and a significant improvement in functional disability in both groups (A,B). Group (A) showed a significant decrease in the PPi scores and significant improvement in functional disability with percentage of improvement was 75%% & 62.5% respectively more than in the group (B) the percentage of improvement was 40% & 46.7% respectively. Conclusion: These results indicate that the lumbo- pelvic stabilizing exercises in conjunction with acupuncture were effective adjunct methods in alleviating postpartum sacroiliac joint pain

EFFECT OF STABILIZING EXERCISES AND ACUPUNCTURE ON POSTPARTUM SACROILIAC PAIN IN EGYPTIAN FEMALES: A RANDOMIZED CONTROL TRIAL

Background: Postpartum sacroiliac joint pain, is a serious problem for the mother, affect the ability to perform daily activities and minimize health-related quality of life. This study aimed to determine the effect of stabilizing exercises and acupuncture on postpartum sacroiliac pain. Methods: Forty multiparous women with sacroiliac joint pain (SIJP), were included, aged 25 to 35 years, BMI not exceed 30kg/m², parity less than 3 times, and delivered normally, they're assigned into two equal groups. Group (A) performed stabilizing exercises for lumbo-pelvic muscles and acupuncture. Group (B) received only acupuncture, were performed three times per week for two months (24sessions). The assessment throughout the present pain intensity (PPi) and the Oswestery disability questionnaire before and after the treatment. Results: It revealed a significant decrease in the PPi scores and a significant improvement in functional disability in both groups (A,B). Group (A) showed a significant decrease in the PPi scores and significant improvement in functional disability with percentage of improvement was 75%% & 62.5% respectively more than in the group (B) the percentage of improvement was 40% & 46.7% respectively. Conclusion: These results indicate that the lumbo- pelvic stabilizing exercises in conjunction with acupuncture were effective adjunct methods in alleviating postpartum sacroiliac joint pain

The effect of relaxation techniques on hypertension secondary to menopause

Context Hypertension after menopause sets women up for an increased risk of negative cardiovascular outcomes. A variety of relaxation techniques exist, which aim to relieve stress and reduce blood pressure. Several studies have been conducted to demonstrate the role of several relaxation techniques in lowering the blood pressure in hypertensive patients. Aim The aim of this study was to determine the effect of relaxation techniques on postmenopausal hypertension. Participants and methods Forty postmenopausal hypertensive women were selected randomly from the outpatient clinic at El Agouza Hospital. They were divided randomly into two groups (A, B): group A was treated with antihypertensive drugs (captopril 25 mg twice daily) and relaxation technique sessions (each session 20 min, three times per week for 3 months), whereas group B was treated with antihypertensive drugs (captopril 25 mg twice daily) only. Blood pressure was evaluated before and after performing the program for both groups. Variables were compared using the unpaired t-test, whereas pairwise comparison (pretreatment vs. post-treatment) within the same group was performed using paired t-test. Results Group A, which was treated with antihypertensive drugs and relaxation techniques, showed a statistically highly significant difference (P<0.01) in both diastolic blood pressure and systolic blood pressure compared with group B, as the mean difference was 12.5 and 3.5, respectively, in the diastolic blood pressure of groups A and B and 15.25 and 6.75 in the systolic blood pressure in groups A and B before and after performing the program, respectively. Conclusion The practice of relaxation techniques was a very effective method in reducing blood pressure in postmenopausal women

Impact of foot reflexology combined with dietary modification on premenstrual syndrome: A randomized controlled trial

Article accepted.The article will be published here soon.Pending final quality checks

L-thyroxine modifies nephrotoxicity by regulating the apoptotic pathway: The possible role of CD38/ADP-ribosyl cyclase-mediated calcium mobilization - Fig 3

<p>(A-D) Kidneys of CIS (15mg/kg) administrated mouse showing (A) vacuolar degeneration (arrow) and necrosis of the renal tubular epithelial linings, hyaline droplets (dashed arrow) and hyaline cast (arrow head). (B) Many apoptotic cells and bodies (arrow) with presence of granular cast (dashed arrow) in the lumen of renal tubules. (C) Wide spread hyaline cast (H) in the lumen of the medullary tubules. (D) Glomerular congestion, hyperplasia of the podocytes and shrinkage of the glomerular tuft (arrow), notice the wide spread of hyaline droplets (upper left) in many tubules. (E-F) Kidney of IRR (6 Gy) mouse showing marked swelling, granular and vacuolar (upper left) degeneration of the renal tubular epithelial linings with many necrotic cells and granular cast (arrow) in the lumen of some tubules. (G) Kidney of CIS and L-TH pretreated mouse showing mild degeneration of the renal tubular epithelium with scattered necrotic cells and small granular cast in the lumen of few tubules (arrow). (H) Kidney of IRR and L-TH pretreated mouse showing good restoration of renal tissue with only mild tubular epithelial degenerative changes. (H&E, X400).</p

Effect of L-TH on serum uric acid (A), creatinine (B) and urea nitrogen (C) levels as well as biochemical analysis of oxidative status; H₂O₂ content (D) and catalase activity (E) in kidney tissues of all experimental groups.

<p>Acute renal injury was induced in male Swiss mice by single <i>i</i>.<i>p</i>. injection of cisplatin (15mg/kg) or gamma irradiation (6 Gy). Animals were pretreated with L-TH (1μg/kg) four hours before induction of nephrotoxicity. L-TH- and vehicle-treated mice were served as normal controls. Values are expressed as mean ± SEM (n = 6–8). ^<i>#</i><i>P</i>< 0.05: significantly different versus vehicle treated control; *<i>P</i>< 0.05, **<i>P</i>< 0.01: significantly different versus untreated control. CIS, cisplatin; H₂O₂, hydrogen peroxide; IRR, gamma irradiated; L-TH, L-thyroxine.</p

Effect of L-TH on serum uric acid (A), creatinine (B) and urea nitrogen (C) levels as well as biochemical analysis of oxidative status; H₂O₂ content (D) and catalase activity (E) in kidney tissues of all experimental groups.

<p>Acute renal injury was induced in male Swiss mice by single <i>i</i>.<i>p</i>. injection of cisplatin (15mg/kg) or gamma irradiation (6 Gy). Animals were pretreated with L-TH (1μg/kg) four hours before induction of nephrotoxicity. L-TH- and vehicle-treated mice were served as normal controls. Values are expressed as mean ± SEM (n = 6–8). ^<i>#</i><i>P</i>< 0.05: significantly different versus vehicle treated control; *<i>P</i>< 0.05, **<i>P</i>< 0.01: significantly different versus untreated control. CIS, cisplatin; H₂O₂, hydrogen peroxide; IRR, gamma irradiated; L-TH, L-thyroxine.</p

Pretreatment with L-TH antagonizes cisplatin-induced cellular death and modified the radiosensitivity.

<p><b>(A)</b> Vero cells were pretreated with L-TH (120 nM) for different exposure time before incubation with cisplatin (60μM/24h). L-TH protected the cells from cisplatin induced dose-dependent loss of viability and L-TH protected the cells from cisplatin-induced cell death in time-dependent effect. <b>(B)</b> The cells were pretreated with different doses of L-TH two hours before they were IRR with either 2 or 6 Gy dose levels. Cell viability was determined using MTT assay after 24h incubation. Data are expressed as mean (% of control) ± SEM of three independent experiments. (*) indicates significant difference versus CIS-treated or 2Gy-irradiated cells (*<i>P</i>< 0.05).</p

L-TH protects against CIS and IRR-induced apoptosis.

<p>Immunohistochemistry for caspase-3 and Bax showing positive expression among the renal tubular epithelium in both models of nephrotoxicity. Very mild to negative expressions of caspase-3 and Bax among the tubular epithelial linings in kidneys of pre-administered L-TH/cisplatin or L-TH/gamma irradiated mice (X 400).</p