116 research outputs found
An evaluation of the relative efficacy of an open airway, an oxygen reservoir and continuous positive airway pressure 5 cmH2O on the non-ventilated lung
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsThe aim of this study, during one-lung ventilation, was to evaluate if oxygenation could be improved by use of a simple oxygen reservoir or application of 5 cmH2O continuous positive airway pressure (CPAP) to the non-ventilated lung compared with an open airway. Twenty-three patients with lung malignancy, undergoing thoracotomy requiring at least 60 minutes of one-lung ventilation before lung lobe excision, were studied. After routine induction and establishment of one-lung ventilation, the three treatments were applied in turn to the same patient in a sequence selected randomly. The first treatment was repeated as a fourth treatment and these results of the repeated treatment averaged to minimize the effect of slow changes. Arterial oxygenation was measured by an arterial blood gas 15 minutes after the application of each treatment. Twenty patients completed the study. Mean PaO2 (in mmHg) was 210.3 (SD 105.5) in the 'OPEN' treatment, 186.0 (SD 109.2) in the 'RESERVOIR' treatment, and 240.5 (SD 116.0) in the 'CPAP' treatment. This overall difference was not quite significant (P=0.058, paired ANOVA), but comparison of the pairs showed that there was a significant better oxygenation only with the CPAP compared to the reservoir treatments (t=2.52, P=0.021). While the effect on the surgical field was not apparent in most patients, in one patient surgery was impeded during CPAP. Our results show that the use of a reservoir does not give oxygenation better than an open tube, and is less effective than the use of CPAP 5 cmH2O on the non-ventilated lung during one-lung ventilation.J. Slimani, W. J. Russell, C. Jurisevichttp://www.aaic.net.au/Article.asp?D=200404
Conditions for spontaneous homogenization of the Universe
The present-day Universe appears to be homogeneous on very large scales. Yet
when the casual structure of the early Universe is considered, it becomes
apparent that the early Universe must have been highly inhomogeneous. The
current paradigm attempts to answer this problem by postulating the inflation
mechanism However, inflation in order to start requires a homogeneous patch of
at least the horizon size. This paper examines if dynamical processes of the
early Universe could lead to homogenization. In the past similar studies seem
to imply that the set of initial conditions that leads to homogenization is of
measure zero. This essay proves contrary: a set of initial conditions for
spontaneous homogenization of cosmological models can form a set of non-zero
measure.Comment: 7 pages. Fifth Award in the 2010 Gravity Research Foundation essay
competitio
Gravitational waves from coalescing binaries and Doppler experiments
Doppler tracking of interplanetary spacecraft provides the only method
presently available for broad-band searches of low frequency gravitational
waves. The instruments have a peak sensitivity around the reciprocal of the
round-trip light-time T of the radio link connecting the Earth to the
space-probe and therefore are particularly suitable to search for coalescing
binaries containing massive black holes in galactic nuclei. A number of Doppler
experiments -- the most recent involving the probes ULYSSES, GALILEO and MARS
OBSERVER -- have been carried out so far; moreover, in 2002-2004 the CASSINI
spacecraft will perform three 40 days data acquisition runs with expected
sensitivity about twenty times better than that achieved so far. Central aims
of this paper are: (i) to explore, as a function of the relevant instrumental
and astrophysical parameters, the Doppler output produced by in-spiral signals
-- sinusoids of increasing frequency and amplitude (the so-called chirp); (ii)
to identify the most important parameter regions where to concentrate intense
and dedicated data analysis; (iii) to analyze the all-sky and all-frequency
sensitivity of the CASSINI's experiments, with particular emphasis on possible
astrophysical targets, such as our Galactic Centre and the Virgo Cluster.Comment: 52 pages, LaTeX, 19 Postscript Figures, submitted to Phys. Rev.
Computing gravitational waves from slightly nonspherical stellar collapse to black hole: Odd-parity perturbation
Nonspherical stellar collapse to a black hole is one of the most promising
gravitational wave sources for gravitational wave detectors. We numerically
study gravitational waves from a slightly nonspherical stellar collapse to a
black hole in linearized Einstein theory. We adopt a spherically collapsing
star as the zeroth-order solution and gravitational waves are computed using
perturbation theory on the spherical background. In this paper we focus on the
perturbation of odd-parity modes. Using the polytropic equations of state with
polytropic indices and 3, we qualitatively study gravitational waves
emitted during the collapse of neutron stars and supermassive stars to black
holes from a marginally stable equilibrium configuration. Since the matter
perturbation profiles can be chosen arbitrarily, we provide a few types for
them. For , the gravitational waveforms are mainly characterized by a
black hole quasinormal mode ringing, irrespective of perturbation profiles
given initially. However, for , the waveforms depend strongly on the
initial perturbation profiles. In other words, the gravitational waveforms
strongly depend on the stellar configuration and, in turn, on the ad hoc choice
of the functional form of the perturbation in the case of supermassive stars.Comment: 31 pages, accepted for publication in Phys. Rev. D, typos and minor
errors correcte
Gamma-Ray Bursts: The Underlying Model
A pedagogical derivation is presented of the ``fireball'' model of gamma-ray
bursts, according to which the observable effects are due to the dissipation of
the kinetic energy of a relativistically expanding wind, a ``fireball.'' The
main open questions are emphasized, and key afterglow observations, that
provide support for this model, are briefly discussed. The relativistic outflow
is, most likely, driven by the accretion of a fraction of a solar mass onto a
newly born (few) solar mass black hole. The observed radiation is produced once
the plasma has expanded to a scale much larger than that of the underlying
``engine,'' and is therefore largely independent of the details of the
progenitor, whose gravitational collapse leads to fireball formation. Several
progenitor scenarios, and the prospects for discrimination among them using
future observations, are discussed. The production in gamma- ray burst
fireballs of high energy protons and neutrinos, and the implications of burst
neutrino detection by kilometer-scale telescopes under construction, are
briefly discussed.Comment: In "Supernovae and Gamma Ray Bursters", ed. K. W. Weiler, Lecture
Notes in Physics, Springer-Verlag (in press); 26 pages, 2 figure
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